50-198-0180

Estrogen receptor beta Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-0180-Each-of-1 In Stock ₹ 36,897.75

50-198-0180 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Estrogen receptor beta

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ESR2

Gene Alias

ER; ER beta; ER[b]; Erb; Erb2; Erbeta; ER-beta; ESR2; ESRB; ESR-BETA; Estrb; estrogen receptor 2; estrogen receptor 2 (beta); estrogen receptor 2 (ER beta); estrogen receptor 2 beta; Estrogen receptor beta; estrogen receptor beta 1 isoform deletion variant; estrogen receptor beta 4; Nr3a2; Nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta; steroid receptor

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

2100

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q92731

Gene Symbols

ESR2

Immunogen

KLH conjugated synthetic peptide derived from human ER-Beta.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Estrogen Receptor beta (ER beta, NR3A2) protein is approximately 55kD, though multiple isoforms ranging from 36-59kD have been described
  • Human ER beta was initially cloned and characterized from testis
  • Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
  • The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
  • When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
  • There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
  • Estrogen receptor beta (ER beta) binds estrogens with an affinity similar to that of estrogen receptor alpha
  • Some ER beta isoforms dominantly inhibit the activity of estrogen receptor alpha in reproductive tissues
  • ER beta is found widely in many tissues throughout the body and can act as a potent tumor suppressor, playing a crucial role in many cancer types such as prostate cancer, autism spectrum disorder, medullary thyroid carcinoma, De Quervain Disease and risk of cardiovascular disease.

Compare Similar Items

Show Difference

Img

Bioss

50-198-0180

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Antigen:
Estrogen receptor beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ESR2

Gene Alias:
ER; ER beta; ER[b]; Erb; Erb2; Erbeta; ER-beta; ESR2; ESRB; ESR-BETA; Estrb; estrogen receptor 2; estrogen receptor 2 (beta); estrogen receptor 2 (ER beta); estrogen receptor 2 beta; Estrogen receptor beta; estrogen receptor beta 1 isoform deletion variant; estrogen receptor beta 4; Nr3a2; Nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta; steroid receptor

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2100

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q92731

Gene Symbols:
ESR2

Immunogen:
KLH conjugated synthetic peptide derived from human ER-Beta.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0181

--


Antigen:
MAG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAG

Gene Alias:
1B236; Brain neuron cytoplasmic protein 3; GMA; MAG; myelin associated glycoprotein; Myelin-associated glycoprotein; sialic acid binding Ig-like lectin 4A; Sialic acid-binding Ig-like lectin 4a; sialic acid-binding immunoglobulin-like lectin 4A; SIGLEC4A; Siglec-4a; S-MAG; S-MAG (C-term.); SPG75

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4099

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P20916

Gene Symbols:
MAG

Immunogen:
KLH conjugated synthetic peptide derived from human MAG.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0182

--


Antigen:
MAG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAG

Gene Alias:
1B236; Brain neuron cytoplasmic protein 3; GMA; MAG; myelin associated glycoprotein; Myelin-associated glycoprotein; sialic acid binding Ig-like lectin 4A; Sialic acid-binding Ig-like lectin 4a; sialic acid-binding immunoglobulin-like lectin 4A; SIGLEC4A; Siglec-4a; S-MAG; S-MAG (C-term.); SPG75

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4099

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P20916

Gene Symbols:
MAG

Immunogen:
KLH conjugated synthetic peptide derived from human MAG.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0183

--


Antigen:
Insulin Receptor Alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
4932439J01Rik; CD220; CD220 beta; CD221; D630014A15Rik; HHF5; IGF-I receptor; Insr; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR beta; IR-A; IR-B

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3643

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P06213

Gene Symbols:
INSR

Immunogen:
KLH conjugated synthetic peptide derived from human Insulin Receptor Alpha.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG