50-198-0242
ARC/Arg3.1 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-0242-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-0242 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
ARC/Arg3.1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Arc
Gene Alias
activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; Activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; Activity-regulated gene 3.1 protein homolog; ARC; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; Arg3.1; Arg3.1/ARC; BOS_13711; C86064; Growth factor ARC; hArc; KIAA0278; mArc; rg3.1; RGD:62037}
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
23237
Content And Storage
-20°C
Form
Liquid
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q7LC44
Gene Symbols
Arc
Immunogen
KLH conjugated synthetic peptide derived from human ARC .
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Master regulator of synaptic plasticity that self-assembles into virion-like capsids that encapsulate RNAs and mediate intercellular RNA transfer in the nervous system
- ARC protein is released from neurons in extracellular vesicles that mediate the transfer of ARC mRNA into new target cells, where ARC mRNA can undergo activity-dependent translation
- ARC capsids are endocytosed and are able to transfer ARC mRNA into the cytoplasm of neurons
- Acts as a key regulator of synaptic plasticity: required for protein synthesis-dependent forms of long-term potentiation (LTP) and depression (LTD) and for the formation of long-term memory
- Regulates synaptic plasticity by promoting endocytosis of AMPA receptors (AMPARs) in response to synaptic activity: this endocytic pathway maintains levels of surface AMPARs in response to chronic changes in neuronal activity through synaptic scaling, thereby contributing to neuronal homeostasis
- Acts as a postsynaptic mediator of activity-dependent synapse elimination in the developing cerebellum by mediating elimination of surplus climbing fiber synapses
- Accumulates at weaker synapses, probably to prevent their undesired enhancement
- This suggests that ARC-containing virion-like capsids may be required to eliminate synaptic material
- Required to transduce experience into long-lasting changes in visual cortex plasticity and for long-term memory
- Involved in postsynaptic trafficking and processing of amyloid-beta A4 (APP) via interaction with PSEN1
- In addition to its role in synapses, also involved in the regulation of the immune system: specifically expressed in skin-migratory dendritic cells and regulates fast dendritic cell migration, thereby regulating T-cell activation.
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Antigen: ARC/Arg3.1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Arc
Gene Alias: activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; Activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; Activity-regulated gene 3.1 protein homolog; ARC; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; Arg3.1; Arg3.1/ARC; BOS_13711; C86064; Growth factor ARC; hArc; KIAA0278; mArc; rg3.1; RGD:62037}
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23237
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q7LC44
Gene Symbols: Arc
Immunogen: KLH conjugated synthetic peptide derived from human ARC .
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ARC/Arg3.1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Arc
Gene Alias:
activity regulated cytoskeletal-associated protein; activity regulated cytoskeleton associated protein; Activity-regulated cytoskeleton-associated protein; Activity-regulated gene 3.1 protein; Activity-regulated gene 3.1 protein homolog; ARC; arc {ECO:0000312; ARC/ARG3.1; Arc3.1; Arg3.1; Arg3.1/ARC; BOS_13711; C86064; Growth factor ARC; hArc; KIAA0278; mArc; rg3.1; RGD:62037}
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23237
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q7LC44
Gene Symbols:
Arc
Immunogen:
KLH conjugated synthetic peptide derived from human ARC .
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: HOXc8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HOXC8
Gene Alias: D130011F21Rik; homeo box 3A; homeo box C8; homeobox C8; Homeobox gene C8; Homeobox protein Hox-3.1; Homeobox protein Hox-3A; Homeobox protein Hox-C8; Homeobox protein M31; homeobox protein R4; HOX3; Hox-3.1; Hox-3.1, mouse, homolog of; HOX3A; Hox3r4; HOXC8; Hoxc-8
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3224
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P31273
Gene Symbols: HOXC8
Immunogen: KLH conjugated synthetic peptide derived from human HOXc8 .
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HOXc8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HOXC8
Gene Alias:
D130011F21Rik; homeo box 3A; homeo box C8; homeobox C8; Homeobox gene C8; Homeobox protein Hox-3.1; Homeobox protein Hox-3A; Homeobox protein Hox-C8; Homeobox protein M31; homeobox protein R4; HOX3; Hox-3.1; Hox-3.1, mouse, homolog of; HOX3A; Hox3r4; HOXC8; Hoxc-8
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3224
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P31273
Gene Symbols:
HOXC8
Immunogen:
KLH conjugated synthetic peptide derived from human HOXc8 .
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: VCAM-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: VCAM1
Gene Alias: CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; Vascular cell adhesion protein 1; V-CAM 1; VCAM1; Vcam-1; VCAM1B
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7412
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P19320
Gene Symbols: VCAM1
Immunogen: KLH conjugated synthetic peptide derived from mouse VCAM-1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
VCAM-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
VCAM1
Gene Alias:
CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; Vascular cell adhesion protein 1; V-CAM 1; VCAM1; Vcam-1; VCAM1B
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7412
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P19320
Gene Symbols:
VCAM1
Immunogen:
KLH conjugated synthetic peptide derived from mouse VCAM-1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Deltex 1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Dtx1
Gene Alias: deltex 1; deltex 1 homolog (Drosophila); deltex 1, E3 ubiquitin ligase; deltex E3 ubiquitin ligase 1; deltex homolog 1; Deltex1; Dtx1; E3 ubiquitin-protein ligase DTX1; fractionated x-irradiation induced transcript 1; Fxit1; FXI-T1; hDTX1; hDx-1; mDTX1; mKIAA4160; Protein deltex-1; RING-type E3 ubiquitin transferase DTX1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1840
Content And Storage: -20°C
Form: Liquid
Applications: ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q86Y01
Gene Symbols: Dtx1
Immunogen: KLH conjugated synthetic peptide derived from human Deltex-1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Deltex 1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Dtx1
Gene Alias:
deltex 1; deltex 1 homolog (Drosophila); deltex 1, E3 ubiquitin ligase; deltex E3 ubiquitin ligase 1; deltex homolog 1; Deltex1; Dtx1; E3 ubiquitin-protein ligase DTX1; fractionated x-irradiation induced transcript 1; Fxit1; FXI-T1; hDTX1; hDx-1; mDTX1; mKIAA4160; Protein deltex-1; RING-type E3 ubiquitin transferase DTX1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1840
Content And Storage:
-20°C
Form:
Liquid
Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q86Y01
Gene Symbols:
Dtx1
Immunogen:
KLH conjugated synthetic peptide derived from human Deltex-1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG