50-198-0260

Tau protein Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-0260-Each-of-1 In Stock ₹ 36,897.75

50-198-0260 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Tau protein

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAPT

Gene Alias

AI413597; AW045860; BOS_19251; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; Mapt; MAPTL; MGC138549; microtubule associated protein tau; Microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Neuronal Marker; Paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; Tau-4; Tau5

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4137

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P10636

Gene Symbols

MAPT

Immunogen

KLH conjugated synthetic peptide derived from human Tau protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Tau is a neuronal microtubule-associated protein found predominantly on axons
  • The function of Tau is to promote tubulin polymerization and stabilize microtubules
  • The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
  • Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
  • The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
  • In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer′s diseases (AD) brain
  • Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, ultimately leading to the degeneration of the affected neurons
  • Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
  • Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick′s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Compare Similar Items

Show Difference

Img

Bioss

50-198-0260

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Antigen:
Tau protein

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597; AW045860; BOS_19251; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; Mapt; MAPTL; MGC138549; microtubule associated protein tau; Microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Neuronal Marker; Paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; Tau-4; Tau5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4137

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P10636

Gene Symbols:
MAPT

Immunogen:
KLH conjugated synthetic peptide derived from human Tau protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0262

--


Antigen:
DR3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFRSF25

Gene Alias:
APO3; Apo-3; apoptosis inducing receptor; Apoptosis-inducing receptor AIR; Apoptosis-mediating receptor DR3; Apoptosis-mediating receptor TRAMP; DDR3; death domain receptor 3 soluble form; Death receptor 3; death receptor beta; DR3; LARD; Lymphocyte-associated receptor of death; Protein WSL; Protein WSL-1; RP4-650H14.2; TNF receptor superfamily member 25; TNFRSF12; TNFRSF25; TR3; TRAMP; Tumor necrosis factor receptor superfamily member 25; tumor necrosis factor receptor superfamily, member 12; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein); tumor necrosis factor receptor superfamily, member 25; UNQ455/PRO779; WSL; WSL1; WSL-1; WSL-LR

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8718

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q93038

Gene Symbols:
TNFRSF25

Immunogen:
KLH conjugated synthetic peptide derived from human DR3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0263

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Antigen:
MMP-7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MMP7

Gene Alias:
BOS_14257; HGNC:7174; MAT; Matrilysin; matrilysin, uterine; Matrin; matrix metallo protease; matrix metallopeptidase 7; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); matrix metalloproteinase 7 (matrilysin, uterine); Matrix metalloproteinase-7; MMP; MMP 7; Mmp7; Mmp-7; MMPs; MPMM; MPSL1; PUMP 1; Pump 1 protease; PUMP1; PUMP-1; Pump-1 protease; uterine matrilysin; Uterine metalloproteinase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4316

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P09237

Gene Symbols:
MMP7

Immunogen:
KLH conjugated synthetic peptide derived from mouse MMP7.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0265

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Antigen:
MOG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MOG

Gene Alias:
B230317G11Rik; BTN6; BTNL11; DAQB-92E24.2; dystonia 2, torsion (autosomal recessive); MGC26137; Mog; MOG alpha 6; MOG alpha-5; MOG alpha-6; MOG AluA; MOG AluB; MOG Ig AluB; MOG Ig-AluB; MOGIG2; MOGIG-2; myelin oligodendrocyte glycoprotein; Myelin-oligodendrocyte glycoprotein; NRCLP7

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4340

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q16653

Gene Symbols:
MOG

Immunogen:
KLH conjugated synthetic peptide derived from human MOG.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG