50-198-0267

DISC1 NT Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Each of 1 50-198-0267-Each-of-1 In Stock ₹ 36,897.75

50-198-0267 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

DISC1 NT

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DISC1

Gene Alias

C1orf136; DISC1; disrupted in schizophrenia 1; Disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

27185

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q9NRI5

Gene Symbols

DISC1

Immunogen

KLH conjugated synthetic peptide derived from human DISC1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • DISC1 (Disrupted in Schizophrenia 1) is a multifunctional protein that interacts with multiple proteins of the centrosome and cytoskeletal system, and is involved in neuronal functions that are dependent upon proper cytoskeletal regulation, including neuronal migration, neurite architecture and intracellular transport
  • Regions of the brain which express DISC1 include the hippocampus, lateral septum, amygdala, cerebral cortex, cerebellum and paraventricular hypothalamus, and loss of DISC1 function results in differences in structural organization.The DISC1 gene locus is associated with patients afflicted with schizophrenia as a result of chromosomal translocations
  • DISC-1 encodes a large protein predicted to contain a globular N-terminal domain and a helical C-terminal domain, both of which have the potential to form interactions with other proteins
  • DISC-1 interacts with proteins involved in the centrosome and cytoskeletal system, including MIPT3, MAP1A and NUDEL; proteins which localize receptors to membranes, including alpha-actinin 2, beta 4-spectrin; and proteins which transduce signals from membrane receptors, including ATF-4 and ATF-5
  • Therefore, DISC-1 is thought to be involved in intracellular transport, neurite architecture and/or neuronal migration, all of which are thought to be pathogenic in the schizophrenic brain
  • Decreased expression of DISC1 in neurons caused an accelerated rate of neuronal integration, resulting in aberrant morphological development, suggesting that DISC1 plays a role in dendritic development and synapse formation
  • DISC-1 is thought to be involved in intracellular transport, neurite architecture and/or neuronal migration, all of which are thought to be pathogenic in the schizophrenic brain.

Compare Similar Items

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Img

Bioss

50-198-0267

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Antigen:
DISC1 NT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DISC1

Gene Alias:
C1orf136; DISC1; disrupted in schizophrenia 1; Disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
27185

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9NRI5

Gene Symbols:
DISC1

Immunogen:
KLH conjugated synthetic peptide derived from human DISC1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0268

--


Antigen:
WNK4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Wnk4

Gene Alias:
2010002J11Rik; Ac2-059; Pha2b; PRKWNK4; Protein kinase lysine-deficient 4; Protein kinase with no lysine 4; protein kinase, lysine deficient 4; protein kinase, lysine-deficient 4; RP23-281C18.8; Serine/threonine-protein kinase WNK4; WNK lysine deficient protein kinase 4; WNK4; WNK4 Ser/Thr kinase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
65266

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q96J92

Gene Symbols:
Wnk4

Immunogen:
KLH conjugated synthetic peptide derived from human WNK4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0271

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Antigen:
ADAMTS7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADAMTS7

Gene Alias:
a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein; a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 7; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 7; ADAM metallopeptidase with thrombospondin type 1 motif, 7; ADAMs; ADAM-TS 7; Adamts7; ADAM-TS7; ADAMTS-7; ADAMTS7B; COMPase; metalloendopeptidases; metalloprotease

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11173

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9UKP4

Gene Symbols:
ADAMTS7

Immunogen:
KLH conjugated synthetic peptide derived from human ADAMTS7.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0272

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Antigen:
Factor 8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
F8

Gene Alias:
AHF; Antihemophilic factor; CF8; Cf-8; Coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8c; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2157

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P00451

Gene Symbols:
F8

Immunogen:
KLH conjugated synthetic peptide derived from rat factor VIII.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG