50-198-0436
B7H4 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-0436-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-0436 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
B7H4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Vtcn1
Gene Alias
B7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7s1; B7X; BC032925; EMBL:AAH95842.1}; FLJ22418; Immune costimulatory protein B7-H4; PRO1291; Protein B7S1; RGD1311204; RP11-229A19.4; T cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; UNQ659/PRO1291; VCTN1; V-set domain containing T cell activation inhibitor 1; V-set domain containing T-cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; VTCN1; vtcn1 {ECO:0000312
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
79679
Content And Storage
-20°C
Form
Liquid
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q7Z7D3
Gene Symbols
Vtcn1
Immunogen
KLH conjugated synthetic peptide derived from Rat B7H4 .
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- B7-H4 (B7x, VTCN1) a costimulatory protein which is reported to function as a negative regulator of T-cell mediated immunity
- Although B7-H4 binds an unknown receptor, it is thought to deliver an inhibitory signal to T-cells preventing their proliferation, cell cycle progression and interleukin-2 production
- B7-H4 deficient mice are only minimally affected; suggesting B7-H4 is important in the fine tuning of the T-cell mediated immune response
- B7-H4 is expressed on activated T-cells, B-cells, monocytes and dendritic cells
- Aberrant expression has been associated with cancers of the lung, breast and ovary in humans
- B7-H4 is expressed primarily on the membrane of lymphoid cells, and as an immunoinhibitory protein that interacts with receptors on the surface of T lymphocytes, it is involved in mediating cellular and humoral immune responses
- Overexpression of B7-H4 is associated with certain malignancies, including ovarian and breast cancer, which may be a mechanism by which tumor cells suppress T cell immunity and facilitate tumor progression
- Further, VTCN1 may be a useful biomarker for the early detection of ovarian cancer and Renal Cell Carcinoma (RCC).
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Antigen: B7H4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Vtcn1
Gene Alias: B7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7s1; B7X; BC032925; EMBL:AAH95842.1}; FLJ22418; Immune costimulatory protein B7-H4; PRO1291; Protein B7S1; RGD1311204; RP11-229A19.4; T cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; UNQ659/PRO1291; VCTN1; V-set domain containing T cell activation inhibitor 1; V-set domain containing T-cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; VTCN1; vtcn1 {ECO:0000312
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 79679
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q7Z7D3
Gene Symbols: Vtcn1
Immunogen: KLH conjugated synthetic peptide derived from Rat B7H4 .
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
B7H4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Vtcn1
Gene Alias:
B7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7s1; B7X; BC032925; EMBL:AAH95842.1}; FLJ22418; Immune costimulatory protein B7-H4; PRO1291; Protein B7S1; RGD1311204; RP11-229A19.4; T cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; UNQ659/PRO1291; VCTN1; V-set domain containing T cell activation inhibitor 1; V-set domain containing T-cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; VTCN1; vtcn1 {ECO:0000312
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
79679
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q7Z7D3
Gene Symbols:
Vtcn1
Immunogen:
KLH conjugated synthetic peptide derived from Rat B7H4 .
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FGFR2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FGFR2
Gene Alias: AU043015; AW556123; bacteria-expressed kinase; BBDS; BEK; BEK fibroblast growth factor receptor; BFR-1; CD332; CEK3; CFD1; Ect1; FGF Receptor 2; FGF-10; Fgfr2; FGFR-2; Fgfr7; Fgfr-7; Fibroblast growth factor receptor 2; JWS; Keratinocyte growth factor receptor; KGFR; KGFRTr; KSAM; K-sam; protein tyrosine kinase, receptor like 14; Soluble KGFR; svs; TK14; TK25
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2263
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P21802
Gene Symbols: FGFR2
Immunogen: KLH conjugated synthetic peptide derived from human FGFR2 .
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FGFR2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FGFR2
Gene Alias:
AU043015; AW556123; bacteria-expressed kinase; BBDS; BEK; BEK fibroblast growth factor receptor; BFR-1; CD332; CEK3; CFD1; Ect1; FGF Receptor 2; FGF-10; Fgfr2; FGFR-2; Fgfr7; Fgfr-7; Fibroblast growth factor receptor 2; JWS; Keratinocyte growth factor receptor; KGFR; KGFRTr; KSAM; K-sam; protein tyrosine kinase, receptor like 14; Soluble KGFR; svs; TK14; TK25
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2263
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin)
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P21802
Gene Symbols:
FGFR2
Immunogen:
KLH conjugated synthetic peptide derived from human FGFR2 .
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FGFR4/CD334
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Fgfr4
Gene Alias: CD334; CTLA-2-beta protein; FGF Receptor 4; FGFR4; Fgfr-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; Protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2264
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P22455
Gene Symbols: Fgfr4
Immunogen: KLH conjugated synthetic peptide derived from human FGFR4 .
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FGFR4/CD334
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Fgfr4
Gene Alias:
CD334; CTLA-2-beta protein; FGF Receptor 4; FGFR4; Fgfr-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; Protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2264
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P22455
Gene Symbols:
Fgfr4
Immunogen:
KLH conjugated synthetic peptide derived from human FGFR4 .
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Dnmt1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DNMT1
Gene Alias: ADCADN; AIM; CXXC9; CXXC-type zinc finger protein 9; DNA (cytosine-5-)-methyltransferase 1; DNA (cytosine-5)-methyltransferase 1; DNA methyltransferase (cytosine-5) 1; DNA methyltransferase 1; DNA methyltransferase HsaI; DNA methyltransferase I; DNA methyltransferase MmuI; DNA MTase HsaI; DNA MTase MmuI; DNA MTase RnoIP; Dnmt; Dnmt1; Dnmt1o; FLJ16293; HSN1E; m.HsaI; m.MmuI; m.RnoIP; MCMT; Met1; Met-1; MGC104992; MommeD2; MTase; Uim
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1786
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P26358
Gene Symbols: DNMT1
Immunogen: KLH conjugated synthetic peptide derived from human Dnmt1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Dnmt1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DNMT1
Gene Alias:
ADCADN; AIM; CXXC9; CXXC-type zinc finger protein 9; DNA (cytosine-5-)-methyltransferase 1; DNA (cytosine-5)-methyltransferase 1; DNA methyltransferase (cytosine-5) 1; DNA methyltransferase 1; DNA methyltransferase HsaI; DNA methyltransferase I; DNA methyltransferase MmuI; DNA MTase HsaI; DNA MTase MmuI; DNA MTase RnoIP; Dnmt; Dnmt1; Dnmt1o; FLJ16293; HSN1E; m.HsaI; m.MmuI; m.RnoIP; MCMT; Met1; Met-1; MGC104992; MommeD2; MTase; Uim
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1786
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P26358
Gene Symbols:
DNMT1
Immunogen:
KLH conjugated synthetic peptide derived from human Dnmt1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG