50-198-0471

Cyclooxygenase 2 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-0471-Each-of-1 In Stock ₹ 36,897.75

50-198-0471 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Cyclooxygenase 2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PTGS2

Gene Alias

Coii; Cox2; Cox-2; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; Cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; Glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; Mtco2; mt-Co2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; Prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; Prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5743

Content And Storage

-20°C

Form

Liquid

Applications

ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P35354

Gene Symbols

PTGS2

Immunogen

KLH conjugated synthetic peptide derived from mouse Cyclooxygenase 2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • COX2 converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis, including production of inflammatory prostaglandins
  • The conversion of arachidonate to prostaglandin H2 is a 2 step reaction: a cyclooxygenase (COX) reaction which converts arachidonate to prostaglandin G2 (PGG2) and a peroxidase reaction in which PGG2 is reduced to prostaglandin H2 (PGH2)
  • It is constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and is up-regulated under pathological conditions, such as in cancer and inflammation (in contrast to the iso-enzyme PTGS1, which is expressed ubiquitously)
  • Up-regulation of COX2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis
  • In cancer cells, COX2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis
  • COX2 is naturally inhibited by calcitriol (the active form of Vitamin D)
  • Glucocorticoids chronically trans-repress PTGS2 gene activity in vivo in part by interfering with transcription initiation and elongation
  • COX2 is a target of NSAID such as aspirin, which can reduce pain and swelling from inflammation driven by COX2.

Compare Similar Items

Show Difference

Img

Bioss

50-198-0471

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Antigen:
Cyclooxygenase 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTGS2

Gene Alias:
Coii; Cox2; Cox-2; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; Cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; Glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; Mtco2; mt-Co2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; Prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; Prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5743

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P35354

Gene Symbols:
PTGS2

Immunogen:
KLH conjugated synthetic peptide derived from mouse Cyclooxygenase 2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0472

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Antigen:
ADAMTS7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADAMTS7

Gene Alias:
a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein; a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 7; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 7; ADAM metallopeptidase with thrombospondin type 1 motif, 7; ADAMs; ADAM-TS 7; Adamts7; ADAM-TS7; ADAMTS-7; ADAMTS7B; COMPase; metalloendopeptidases; metalloprotease

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11173

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9UKP4

Gene Symbols:
ADAMTS7

Immunogen:
KLH conjugated synthetic peptide derived from mouse ADAMTS7 .

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0473

--


Antigen:
KGF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FGF7

Gene Alias:
Fgf7; Fgf-7; Fibroblast growth factor 7; fibroblast growth factor 7 (keratinocyte growth factor); HBGF-7; Heparin-binding growth factor 7; Keratinocyte growth factor; Kgf

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2252

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P21781

Gene Symbols:
FGF7

Immunogen:
KLH conjugated synthetic peptide derived from human KGF/Fibroblast growth factor 7.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0474

--


Antigen:
FGF8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FGF8

Gene Alias:
Aigf; androgen-induced; Androgen-induced growth factor; FGF; FGF8; FGF-8; Fibroblast growth factor; Fibroblast growth factor 8; fibroblast growth factor 8 (androgen-induced); HBGF-8; Heparin-binding growth factor 8; HH6; KAL6; MGC149376

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2253

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P55075

Gene Symbols:
FGF8

Immunogen:
KLH conjugated synthetic peptide derived from mouse FGF8 .

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG