50-198-0727

PDZ RHOGEF/GTRAP48 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-0727-Each-of-1 In Stock ₹ 36,897.75

50-198-0727 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

PDZ RHOGEF/GTRAP48

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ARHGEF11

Gene Alias

ARHGEF11; B930073M02; E130307F09; glutamate transporter EAAT4 associated protein 48; glutamate transporter EAAT4-associated protein 48; GTRAP48; KIAA0380; mKIAA0380; PDZ-RhoGEF; Prg; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; Rho guanine nucleotide exchange factor 11; RhoA-specific guanine nucleotide exchange factor; RhoGEF; RhoGEF glutamate transport modulator; RhoGEF glutamate transport modulator GTRAP48; RP11-356J7.2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

9826

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O15085

Gene Symbols

ARHGEF11

Immunogen

KLH conjugated synthetic peptide derived from human PDZ RHOGEF/GTRAP48.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • ARHGEF11 is a 1527 amino acid protein with tandem dbl homology and pleckstrin homology domains, PDZ domain, two proline rich sequences and a regulatory G protein-signaling (RGS) sequence
  • It acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase, but not for RAC1 or CDC42 and acts as GTPase-activating protein (GAP) for GNA12 and GNA13
  • It forms a complex with G proteins and stimulates neurite through retraction Rho-dependent signals
  • ARHGEF11 increases glutamate transport 4-fold
  • It interacts with EAAT4 and modulates its uptake activity and perisynaptic distribution at glutamatergic synapses
  • It is known to induce the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia
  • It is ubiquitously expressed, in brain, lung, liver, kidney and skeletal muscle.

Compare Similar Items

Show Difference

Img

Bioss

50-198-0727

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Antigen:
PDZ RHOGEF/GTRAP48

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARHGEF11

Gene Alias:
ARHGEF11; B930073M02; E130307F09; glutamate transporter EAAT4 associated protein 48; glutamate transporter EAAT4-associated protein 48; GTRAP48; KIAA0380; mKIAA0380; PDZ-RhoGEF; Prg; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; Rho guanine nucleotide exchange factor 11; RhoA-specific guanine nucleotide exchange factor; RhoGEF; RhoGEF glutamate transport modulator; RhoGEF glutamate transport modulator GTRAP48; RP11-356J7.2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9826

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O15085

Gene Symbols:
ARHGEF11

Immunogen:
KLH conjugated synthetic peptide derived from human PDZ RHOGEF/GTRAP48.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0728

--


Antigen:
CD274

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cd274

Gene Alias:
A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; PDCD1L1; Pdcd1lg1; PDL1; PD-L1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
29126

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9NZQ7

Gene Symbols:
Cd274

Immunogen:
KLH conjugated synthetic peptide derived from human CD274.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0729

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Antigen:
BRMS-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BRMS1

Gene Alias:
AV003220; AW554636; breast cancer metastasis suppressor 1; Breast cancer metastasis-suppressor 1; Breast cancer metastasis-suppressor 1 homolog; BRMS 1; BRMS1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
25855

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9HCU9

Gene Symbols:
BRMS1

Immunogen:
KLH conjugated synthetic peptide derived from human BRMS-1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-0730

--


Antigen:
CYP11B2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CYP11B2

Gene Alias:
ALDOS; Aldosterone synthase; Aldosterone-synthesizing enzyme; Corticosterone 18-monooxygenase, CYP11B2; Cp45as; Cpn2; CYP11B; Cyp11b2; Cyp11b-2; Cyp11b3; CYP11BL; CYPXIB2; CYPXIB3; Cytochrome P450 11B2, mitochondrial; cytochrome P450 11B3, mitochondrial; cytochrome P450 family 11 subfamily B member 2; Cytochrome P450 subfamily XIB polypeptide 2 (aldosterone synthase); cytochrome P450, family 11, subfamily B, polypeptide 2; cytochrome P450, subfamily 11B, polypeptide 2; cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2; Cytochrome P450, subfamily XIB, polypeptide 2 (aldosterone synthase); Cytochrome P-450Aldo; cytochrome P450-Aldo-1; cytochrome P450-Aldo-2; Cytochrome P450C11; Cytochrome P-450C18; mitochondrial cytochrome P450, family 11, subfamily B, polypeptide 2; P450aldo; P450-Aldo-1; P450-Aldo-2; P450C 18; P-450C 18; P450C18; P-450C18; RNCP45AS; steroid 11-beta/18-hydroxylase; steroid 11-beta-hydroxylase; Steroid 11-beta-hydroxylase, CYP11B2; steroid 11-beta-monooxygenase; Steroid 18-hydroxylase; steroid 18-hydroxylase, aldosterone synthase, P450C18, P450aldo; steroid-11-beta-hydroxylase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1585

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P19099

Gene Symbols:
CYP11B2

Immunogen:
KLH conjugated synthetic peptide derived from human CYP11B2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG