50-198-0868
Phospho-Nemo-like kinase (Thr298) Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-0868-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-0868 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
Phospho-Nemo-like kinase (Thr298)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NLK
Gene Alias
AI194375; LAK1; nemo like kinase; Nemo-like kinase; Nlk; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; Serine/threonine-protein kinase NLK
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18099, 497961, 51701
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
D3ZSZ3, O54949, Q9UBE8
Gene Symbols
NLK
Immunogen
KLH conjugated synthetic phosphopeptide derived from human Nemo-like kinase around the phosphorylation site of Thr298.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Serine/threonine-protein kinase that regulates a number of transcription factors with key roles in cell fate determination
- Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2
- Activation of this pathway causes binding to and phosphorylation of the histone methyltransferase SETDB1
- The NLK-SETDB1 complex subsequently interacts with PPARG, leading to methylation of PPARG target promoters at histone H3K9 and transcriptional silencing
- The resulting loss of PPARG target gene transcription inhibits adipogenesis and promotes osteoblastogenesis in mesenchymal stem cells (MSCs)
- Negative regulator of the canonical Wnt/beta-catenin signaling pathway
- Binds to and phosphorylates TCF7L2/TCF4 and LEF1, promoting the dissociation of the TCF7L2/LEF1/beta-catenin complex from DNA, as well as the ubiquitination and subsequent proteolysis of LEF1
- Together these effects inhibit the transcriptional activation of canonical Wnt/beta-catenin target genes
- Negative regulator of the Notch signaling pathway
- Binds to and phosphorylates NOTCH1, thereby preventing the formation of a transcriptionally active ternary complex of NOTCH1, RBPJ/RBPSUH and MAML1
- Negative regulator of the MYB family of transcription factors
- Phosphorylation of MYB leads to its subsequent proteolysis while phosphorylation of MYBL1 and MYBL2 inhibits their interaction with the coactivator CREBBP
- Other transcription factors may also be inhibited by direct phosphorylation of CREBBP itself
- Acts downstream of IL6 and MAP3K7/TAK1 to phosphorylate STAT3, which is in turn required for activation of NLK by MAP3K7/TAK1
- Upon IL1B stimulus, cooperates with ATF5 to activate the transactivation activity of C/EBP subfamily members
- Phosphorylates ATF5 but also stabilizes ATF5 protein levels in a kinase-independent manner.
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Antigen: Phospho-Nemo-like kinase (Thr298)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NLK
Gene Alias: AI194375; LAK1; nemo like kinase; Nemo-like kinase; Nlk; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; Serine/threonine-protein kinase NLK
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18099, 497961, 51701
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: D3ZSZ3, O54949, Q9UBE8
Gene Symbols: NLK
Immunogen: KLH conjugated synthetic phosphopeptide derived from human Nemo-like kinase around the phosphorylation site of Thr298.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Nemo-like kinase (Thr298)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NLK
Gene Alias:
AI194375; LAK1; nemo like kinase; Nemo-like kinase; Nlk; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; Serine/threonine-protein kinase NLK
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18099, 497961, 51701
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
D3ZSZ3, O54949, Q9UBE8
Gene Symbols:
NLK
Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Nemo-like kinase around the phosphorylation site of Thr298.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Collagen 1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: COL1A2
Gene Alias: AA960264; AI325291; alpha 1 type I collagen; alpha 2 type I procollagen; alpha 2(I) procollagen; alpha 2(I)-collagen; alpha-1 type 1 collagen; Alpha-1 type I collagen; alpha1(I) procollagen; Alpha-2 type I collagen; BOS_18945; BOS_4009; COL1; Col1a1; Col1a-1; COL1A2; Col1a-2; Cola1; Cola-1; Cola2; Cola-2; COLIA1; collagen alpha 1 chain type I; Collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; Collagen alpha-2(I) chain; collagen COL1A2; collagen I alpha-2 polypeptide; collagen I, alpha-2 polypeptide; collagen of skin, tendon and bone, alpha-1 chain; collagen of skin, tendon and bone, alpha-2 chain; collagen type I alpha 1; collagen type I alpha 2 chain; collagen, type 1, alpha 1; collagen, type I, alpha 1; collagen, type I, alpha 2; EDSC; LOC100347598; Mov13; Mov-13; OI1; OI2; OI3; OI4; oim; osteogenesis imperfecta; pro-alpha-1 collagen type 1; procollagen type I, alpha 1; procollagen, type 1, alpha 1; procollagen, type I, alpha 1; procollagen, type I, alpha 2; Type I Collagen; type I proalpha 1; type I procollagen; type I procollagen alpha 1 chain; type I-alpha 1 collagen
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1277, 1278
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P02452, P08123
Gene Symbols: COL1A1, COL1A2
Immunogen: KLH conjugated synthetic peptide derived from human Collagen I.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Collagen 1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
COL1A2
Gene Alias:
AA960264; AI325291; alpha 1 type I collagen; alpha 2 type I procollagen; alpha 2(I) procollagen; alpha 2(I)-collagen; alpha-1 type 1 collagen; Alpha-1 type I collagen; alpha1(I) procollagen; Alpha-2 type I collagen; BOS_18945; BOS_4009; COL1; Col1a1; Col1a-1; COL1A2; Col1a-2; Cola1; Cola-1; Cola2; Cola-2; COLIA1; collagen alpha 1 chain type I; Collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; Collagen alpha-2(I) chain; collagen COL1A2; collagen I alpha-2 polypeptide; collagen I, alpha-2 polypeptide; collagen of skin, tendon and bone, alpha-1 chain; collagen of skin, tendon and bone, alpha-2 chain; collagen type I alpha 1; collagen type I alpha 2 chain; collagen, type 1, alpha 1; collagen, type I, alpha 1; collagen, type I, alpha 2; EDSC; LOC100347598; Mov13; Mov-13; OI1; OI2; OI3; OI4; oim; osteogenesis imperfecta; pro-alpha-1 collagen type 1; procollagen type I, alpha 1; procollagen, type 1, alpha 1; procollagen, type I, alpha 1; procollagen, type I, alpha 2; Type I Collagen; type I proalpha 1; type I procollagen; type I procollagen alpha 1 chain; type I-alpha 1 collagen
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1277, 1278
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P02452, P08123
Gene Symbols:
COL1A1, COL1A2
Immunogen:
KLH conjugated synthetic peptide derived from human Collagen I.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TSPAN12
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSPAN12
Gene Alias: 9030619E17; AI426782; AI663988; AW111457; BOS_4427; EVR5; LOC100355614; NET2; NET-2; Tetraspan NET-2; tetraspanin 12; Tetraspanin-12; Tm4sf12; Transmembrane 4 superfamily member 12; transmembrane 4 superfamily member 12-like; TSPAN12; Tspan-12; UNQ774/PRO1568; zgc:63880
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23554
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: O95859
Gene Symbols: TSPAN12
Immunogen: KLH conjugated synthetic peptide derived from human TSPAN12.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TSPAN12
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSPAN12
Gene Alias:
9030619E17; AI426782; AI663988; AW111457; BOS_4427; EVR5; LOC100355614; NET2; NET-2; Tetraspan NET-2; tetraspanin 12; Tetraspanin-12; Tm4sf12; Transmembrane 4 superfamily member 12; transmembrane 4 superfamily member 12-like; TSPAN12; Tspan-12; UNQ774/PRO1568; zgc:63880
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23554
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
O95859
Gene Symbols:
TSPAN12
Immunogen:
KLH conjugated synthetic peptide derived from human TSPAN12.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: VAMP-1+2+3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Vamp1
Gene Alias: BOS_6013; DKFZp686H12131; lew; MRXSYP; SPAX1; Syb1; Syb-1; synaptobrevin 1; Synaptobrevin-1; VAMP1; VAMP-1; vesicle associated membrane protein 1; Vesicle-associated membrane protein 1; vesicle-associated membrane protein 1 (synaptobrevin 1)
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6843
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P23763
Gene Symbols: Vamp1
Immunogen: KLH conjugated synthetic peptide derived from human VAMP-1+2+3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
VAMP-1+2+3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Vamp1
Gene Alias:
BOS_6013; DKFZp686H12131; lew; MRXSYP; SPAX1; Syb1; Syb-1; synaptobrevin 1; Synaptobrevin-1; VAMP1; VAMP-1; vesicle associated membrane protein 1; Vesicle-associated membrane protein 1; vesicle-associated membrane protein 1 (synaptobrevin 1)
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6843
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P23763
Gene Symbols:
Vamp1
Immunogen:
KLH conjugated synthetic peptide derived from human VAMP-1+2+3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG