50-198-1158

ACL6B/BAF53b Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-1158-Each-of-1 In Stock ₹ 36,897.75

50-198-1158 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

ACL6B/BAF53b

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Actl6b

Gene Alias

53 kDa BRG1-associated factor B; actin like 6B; actin-like 6; actin-like 6B; Actin-like protein 6B; actin-like protein 6B {ECO:0000250; Actin-related protein Baf53b; Actl6; ACTL6B; actl6b {ECO:0000250; Arpna; ArpNalpha; ArpN-alpha; BAF53B; BRG1-associated factor 53B; hArpN alpha; UniProtKB:O94805}

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

51412

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O94805

Gene Symbols

Actl6b

Immunogen

KLH conjugated synthetic peptide derived from human ACL6B.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Bioss

50-198-1591

--

Img

Bioss

50-198-1084

--

Img

Bioss

50-198-1113

--

Img

Bioss

50-198-1347

--

Img

Bioss

50-198-1076

--

Img

Bioss

50-198-1141

--

Img

Bioss

50-198-1029

--

Img

Bioss

50-198-1062

--

Description

  • Belongs to the chromatin remodeling brain-specific BAF (bBAF) complex, as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion
  • Belongs to the neuron-specific chromatin remodeling complex (nBAF complex) and is required for postmitotic neural development and dendritic outgrowth
  • During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state
  • The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes
  • As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF)
  • The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells
  • The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth
  • ACTL6B/BAF53B is not essential for assembly of the nBAF complex but is required for targeting the complex and CREST to the promoter of genes essential for dendritic growth.

Compare Similar Items

Show Difference

Img

Bioss

50-198-1158

--


Antigen:
ACL6B/BAF53b

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Actl6b

Gene Alias:
53 kDa BRG1-associated factor B; actin like 6B; actin-like 6; actin-like 6B; Actin-like protein 6B; actin-like protein 6B {ECO:0000250; Actin-related protein Baf53b; Actl6; ACTL6B; actl6b {ECO:0000250; Arpna; ArpNalpha; ArpN-alpha; BAF53B; BRG1-associated factor 53B; hArpN alpha; UniProtKB:O94805}

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
51412

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O94805

Gene Symbols:
Actl6b

Immunogen:
KLH conjugated synthetic peptide derived from human ACL6B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1160

--


Antigen:
PRPH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRPH2

Gene Alias:
AOFMD; AVMD; CACD2; DS; MDBS1; Nmf193; peripherin 2; peripherin 2 (retinal degeneration, slow); peripherin 2, homolog of mouse; peripherin, photoreceptor type; Peripherin-2; PRPH; PRPH2; Rd2; Rd-2; Rds; retinal degeneration 2; Retinal degeneration slow protein; retinal degeneration, slow; retinal degeneration, slow (retinitis pigmentosa 7); retinal peripherin; RP7; RSRDS; Tetraspanin-22; TSPAN22; Tspan-22

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5961

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P23942

Gene Symbols:
PRPH2

Immunogen:
KLH conjugated synthetic peptide derived from human PRPH2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1161

--


Antigen:
ProSAPiP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Lzts3

Gene Alias:
KIAA0552; Leucine zipper putative tumor suppressor 3; leucine zipper tumor suppressor family member 3; leucine zipper, putative tumor suppressor family member 3; LZTS3; proline rich synapse associated protein interacting protein 1; proline rich synapse associated protein interacting protein 1 (Prosapip1); ProSAP/Shank-interacting protein 1; ProSAP-interacting protein 1; PROSAPIP1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9762

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O60299

Gene Symbols:
Lzts3

Immunogen:
KLH conjugated synthetic peptide derived from human ProSAPiP1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1162

--


Antigen:
DBX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DBX1

Gene Alias:
AI426026; Dbx; DBX1; developing brain homeobox 1; Developing brain homeobox protein 1; Homeobox protein DBX1; Mmox C

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
120237

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
A6NMT0

Gene Symbols:
DBX1

Immunogen:
KLH conjugated synthetic peptide derived from human DBX1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG