50-198-1214

TMP21 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-1214-Each-of-1 In Stock ₹ 36,897.75

50-198-1214 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

TMP21

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TMED10

Gene Alias

1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; BOS_11050; Integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; RCJMB04_24a4; S31I125; S31III125; testicular tissue protein Li 206; Tmed10; tmed10.L; TMP21; Tmp-21-I; Transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; Transmembrane protein Tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

10972

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P49755

Gene Symbols

TMED10

Immunogen

KLH conjugated synthetic peptide derived from human TMP21.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • TMP21 is a ubiquitously expressed protein that is involved in vesicular targeting and protein transport
  • More recent experiments have shown that it is also a component in the presenilin complex and modulates the -gamma-secretase but not the epsilon-secretase cleavage activity of the amyloid precursor protein
  • The presenilin complex is composed of the proteins APH1, nicastrin, and PEN2 in addition to presenilin-1
  • Together, these proteins cleave the amyloid precursor protein at what is known as the -gamma- and epsilon-sites and can lead to the accumulation of the Abeta cleavage product that is associated with Alzheimer′s disease
  • Co-immunoprecipitation experiments using antibodies against these proteins also yielded TMP21 indicating that TMP21 may play a role in the regulation of this complex
  • Suppression of TMP21 expression by siRNA in transfected cells caused increased -gamma-secretase activity but not epsilon-secretase activity, and increased Abeta production, demonstrating that TMP21 can modulate -gamma-secretase activity.

Compare Similar Items

Show Difference

Img

Bioss

50-198-1214

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Antigen:
TMP21

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMED10

Gene Alias:
1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; BOS_11050; Integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; RCJMB04_24a4; S31I125; S31III125; testicular tissue protein Li 206; Tmed10; tmed10.L; TMP21; Tmp-21-I; Transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; Transmembrane protein Tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10972

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P49755

Gene Symbols:
TMED10

Immunogen:
KLH conjugated synthetic peptide derived from human TMP21.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1215

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Antigen:
C1QBP/GC1q R

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C1QBP

Gene Alias:
AA407365; AA986492; ASF/SF2-associated protein p32; C1q globular domain-binding protein; C1qbp; complement C1q binding protein; Complement component 1 Q subcomponent-binding protein, mitochondrial; complement component 1, q subcomponent binding protein; D11Wsu182e; Gc1qbp; gC1qR; gC1Q-R; gC1q-R protein; Glycoprotein gC1qBP; HABP1; Hyaluronan-binding protein 1; Mitochondrial matrix protein p32; p32; p33; RPA; SF2AP32; SF2P32; splicing factor SF2-associated protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
708

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q07021

Gene Symbols:
C1QBP

Immunogen:
KLH conjugated synthetic peptide derived from human C1QBP.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1216

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Antigen:
MYO6/Myosin VI

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYO6

Gene Alias:
BC029719; DFNA22; DFNB37; KIAA0389; MYO6; myosin VI; myosin-VI; RGD1560646; Snell′s waltzer; sv; tailchaser; Tlc; Unconventional myosin-6; Unconventional myosin-VI

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4646

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9UM54

Gene Symbols:
MYO6

Immunogen:
KLH conjugated synthetic peptide derived from human Myosin VI.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1218

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Antigen:
DERLIN-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DERL1

Gene Alias:
1110021N07Rik; AI195141; AW551338; Degradation in endoplasmic reticulum protein 1; Der1; DER-1; Der1-like domain family, member 1; Der1-like protein 1; DERL1; derlin 1; Derlin-1; DERtrin-1; UNQ243/PRO276

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
79139

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9BUN8

Gene Symbols:
DERL1

Immunogen:
KLH conjugated synthetic peptide derived from human DERLIN-1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG