50-198-1352

STAT3 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-1352-Each-of-1 In Stock ₹ 36,897.75

50-198-1352 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

STAT3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

STAT3

Gene Alias

1110034C02Rik; acute phase response factor; Acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; BOS_19088; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT-3 protein; STAT3b1; STAT3b2; transcription factor; wu:fc15d02; wu:fl59g06; z-Stat3

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6774

Content And Storage

-20°C

Form

Liquid

Applications

Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P40763

Gene Symbols

STAT3

Immunogen

KLH conjugated synthetic peptide derived from human STAT3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
  • Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
  • STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
  • Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
  • In humans, the STAT3 gene is located on the q arm of chromosome 17
  • STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
  • The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
  • STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
  • The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
  • Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
  • Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.

Compare Similar Items

Show Difference

Img

Bioss

50-198-1352

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Antigen:
STAT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAT3

Gene Alias:
1110034C02Rik; acute phase response factor; Acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; BOS_19088; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT-3 protein; STAT3b1; STAT3b2; transcription factor; wu:fc15d02; wu:fl59g06; z-Stat3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6774

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P40763

Gene Symbols:
STAT3

Immunogen:
KLH conjugated synthetic peptide derived from human STAT3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1353

--


Antigen:
NMUR1/GPR66

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NMUR1

Gene Alias:
(FM-3); FM3; FM-3; G protein-coupled receptor 66; G protein-coupled receptor FM-3; GPC-R; GPR66; G-protein coupled receptor 66; G-protein coupled receptor FM-3; neuromedin U receptor 1; Neuromedin-U receptor 1; NMU1R; NmU-R; NMUR1; NMU-R1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10316

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9HB89

Gene Symbols:
NMUR1

Immunogen:
KLH conjugated synthetic peptide derived from human NMUR1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1354

--


Antigen:
NMUR2/GPR-FM4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nmur2

Gene Alias:
FM4; FM-4; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; G-protein-coupled receptor FM-4; growth hormone secretagogue receptor family, member 4; neuromedin U receptor 2; Neuromedin-U receptor 2; NMSR2; NMU2R; Nmur2; NMU-R2; TGR1; TGR-1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
56923

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9GZQ4

Gene Symbols:
Nmur2

Immunogen:
KLH conjugated synthetic peptide derived from human NMUR2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1355

--


Antigen:
NPS/Neuropeptide S

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPS

Gene Alias:
ENSMUSG00000073804; Neuropeptide S; Nps; prepro-neuropeptide S

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
594857

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P0C0P6

Gene Symbols:
NPS

Immunogen:
KLH conjugated synthetic peptide derived from human Neuropeptide S.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG