50-198-1363

MOT8/SLC16A2 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-1363-Each-of-1 In Stock ₹ 36,897.75

50-198-1363 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

MOT8/SLC16A2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Slc16a2

Gene Alias

AHDS; AW105741; DXS128; DXS128E; MCT 7; MCT 8; MCT7; Mct8; Monocarboxylate transporter 7; Monocarboxylate transporter 8; Monocarboxylate transporter 8 (MCT 8) (X-linked PEST-containing transporter); MRX22; SLC16A2; solute carrier family 16 (monocarboxylic acid transporters), member 2; Solute carrier family 16 member 2; solute carrier family 16, member 2 (monocarboxylic acid transporter 8); solute carrier family 16, member 2 (thyroid hormone transporter); X-linked PEST-containing transporter; XPCT

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6567

Content And Storage

-20°C

Form

Liquid

Applications

Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P36021

Gene Symbols

Slc16a2

Immunogen

KLH conjugated synthetic peptide derived from human MOT8/SLC16A2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism
  • Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions
  • However, accumulation of lactic acid leads to a decrease in intracellular pH and cessation of glycolysis
  • In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell
  • This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate
  • The MCT family consists of at least eight members, MCT 1-8, which contain between 10-12 transmembrane-helical (TM) domains, with the amino and carboxy termini located in the cytoplasm
  • Defects in the gene encoding for MCT8, SLC16A2, can cause monocarboxylate transporter 8 deficiency (MCT8 deficiency), a defect in cellular hormone transport causing a severe form of X-linked psychomotor retardation and abnormal thyroid levels.

Compare Similar Items

Show Difference

Img

Bioss

50-198-1363

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Antigen:
MOT8/SLC16A2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Slc16a2

Gene Alias:
AHDS; AW105741; DXS128; DXS128E; MCT 7; MCT 8; MCT7; Mct8; Monocarboxylate transporter 7; Monocarboxylate transporter 8; Monocarboxylate transporter 8 (MCT 8) (X-linked PEST-containing transporter); MRX22; SLC16A2; solute carrier family 16 (monocarboxylic acid transporters), member 2; Solute carrier family 16 member 2; solute carrier family 16, member 2 (monocarboxylic acid transporter 8); solute carrier family 16, member 2 (thyroid hormone transporter); X-linked PEST-containing transporter; XPCT

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6567

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P36021

Gene Symbols:
Slc16a2

Immunogen:
KLH conjugated synthetic peptide derived from human MOT8/SLC16A2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1364

--


Antigen:
NG/Neurogranin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NRGN

Gene Alias:
0710001B06Rik; AI838505; B-50 immunoreactive C-kinase substrate; BICKS; BOS_24593; calmodulin-binding protein; hng; LOC100348879; NEUG(55-78); Neurogranin; neurogranin (protein kinase C substrate, RC3); neurogranin-like; NG; NG/RC3; NRGN; p17; postsynaptic spine 1; protein kinase C substrate; Protein kinase C substrate 7.5 kDa protein; protein kinase C substrate, RC3; Pss1; R75334; RC3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4900

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q92686

Gene Symbols:
NRGN

Immunogen:
KLH conjugated synthetic peptide derived from human NG/Neurogranin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1366

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Antigen:
CRSP77

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MED17

Gene Alias:
77kDa; Activator-recruited cofactor 77 kDa component; ARC77; BOS_24330; C330002H14Rik; Cofactor required for Sp1 transcriptional activation subunit 6; cofactor required for Sp1 transcriptional activation, subunit 6; cofactor required for Sp1 transcriptional activation, subunit 6 (77kD); cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa; CRSP complex subunit 6; CRSP6; CRSP77; DRIP77; DRIP80; LOC100351468; MED17; Mediator complex subunit 17; Mediator of RNA polymerase II transcription subunit 17; Thyroid hormone receptor-associated protein complex 80 kDa component; Transcriptional coactivator CRSP77; Trap80; Vitamin D3 receptor-interacting protein complex 80 kDa component

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9440

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9NVC6

Gene Symbols:
MED17

Immunogen:
KLH conjugated synthetic peptide derived from human CRSP77.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1367

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Antigen:
TRIP13/16E1BP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIP13

Gene Alias:
16E1BP; 16E1-BP; 2410002G23Rik; D13Ertd328e; HPV16 E1 protein binding protein; HPV16 E1 protein-binding protein; Human papillomavirus type 16 E1 protein-binding protein; Pachytene checkpoint protein 2 homolog; Pch2; Thyroid hormone receptor interactor 13; thyroid receptor interacting protein 13; Thyroid receptor-interacting protein 13; TR-interacting protein 13; TRIP13; TRIP-13

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9319

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q15645

Gene Symbols:
TRIP13

Immunogen:
KLH conjugated synthetic peptide derived from human TRIP13/16E1BP.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG