50-198-1415

Unc5a/UNC5H1 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-1415-Each-of-1 In Stock ₹ 36,897.75

50-198-1415 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Unc5a/UNC5H1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Unc5a

Gene Alias

Kiaa1976; mKIAA1976; Netrin receptor UNC5A; netrin receptor Unc5h1; Protein unc-5 homolog 1; Protein unc-5 homolog A; transmembrane receptor Unc5H1; unc5 (C.elegans homolog) a; unc5 homolog 1; unc-5 homolog 1; unc-5 homolog A; unc-5 homolog A (C. elegans); unc-5 netrin receptor A; UNC5A; UNC5H1; UNC5H1FLJ16449

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

90249

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q6ZN44

Gene Symbols

Unc5a

Immunogen

KLH conjugated synthetic peptide derived from human Unc5a.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Bioss

50-198-1414

--

Img

Bioss

50-198-1412

--

Img

Bioss

50-198-1413

--

Img

Bioss

50-198-1397

--

Img

Bioss

50-198-0403

--

Img

Bioss

50-198-1115

--

Img

Bioss

50-198-1350

--

Img

Bioss

50-198-0919

--

Description

  • The UNC5H family of proteins act as transmembrane receptors for netrin-1 and play a crucial role in axon guidance and migration of neural cells
  • Additionally, when cleaved by a caspase to produce an intracellular fragment containing a death domain,UNC5H receptors induce apoptosis
  • This activity is blocked by the binding of netrin-1
  • In the absence of netrin-1, UNC5H receptors act as tumor suppressors by inhibiting anchorage-independent growth and invasion, but mutation of these receptors provides a potential mechanism for tumorigenicity
  • The expression of UNC5H receptors is downregulated in multiple carcinomas, including colorectal, breast, ovary, uterus, stomach, lung and kidney cancers
  • UNC5H1, also known as UNC5HA (unc-5 homolog A), is a member of the UNC5H family of proteins and is localized to the cell membrane
  • Three isoforms of UNC5H1 exist due to alternative splicing events.

Compare Similar Items

Show Difference

Img

Bioss

50-198-1415

--


Antigen:
Unc5a/UNC5H1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Unc5a

Gene Alias:
Kiaa1976; mKIAA1976; Netrin receptor UNC5A; netrin receptor Unc5h1; Protein unc-5 homolog 1; Protein unc-5 homolog A; transmembrane receptor Unc5H1; unc5 (C.elegans homolog) a; unc5 homolog 1; unc-5 homolog 1; unc-5 homolog A; unc-5 homolog A (C. elegans); unc-5 netrin receptor A; UNC5A; UNC5H1; UNC5H1FLJ16449

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
90249

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q6ZN44

Gene Symbols:
Unc5a

Immunogen:
KLH conjugated synthetic peptide derived from human Unc5a.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1416

--


Antigen:
VAX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VAX1

Gene Alias:
BOS_23569; homeodomain protein Vax1; MCOPS11; vax1; Ventral anterior homeobox 1; ventral anterior homeobox containing gene 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11023

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q5SQQ9

Gene Symbols:
VAX1

Immunogen:
KLH conjugated synthetic peptide derived from human VAX1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1417

--


Antigen:
VAX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VAX2

Gene Alias:
Dres93; Vax2; Ventral anterior homeobox 2; ventral anterior homeobox containing gene 2; Ventral retina homeodomain protein; Vex

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
25806

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9UIW0

Gene Symbols:
VAX2

Immunogen:
KLH conjugated synthetic peptide derived from human VAX2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1419

--


Antigen:
CDNF/ARMETL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cdnf

Gene Alias:
9330140G23; Arginine-rich protein mutated in early stage tumors-like 1; arginine-rich, mutated in early stage tumors-like 1; ARMETL1; ARMET-like protein 1; CDNF; Cerebral dopamine neurotrophic factor; Conserved dopamine neurotrophic factor

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
441549

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q49AH0

Gene Symbols:
Cdnf

Immunogen:
KLH conjugated synthetic peptide derived from human ARMETL1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG