50-198-1557

Aggrecan Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-1557-Each-of-1 In Stock ₹ 36,897.75

50-198-1557 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Aggrecan

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ACAN

Gene Alias

Acan; Agc; AGC1; AGCAN; aggrecan; aggrecan 1; aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122); Aggrecan core protein; Aggrecan core protein 2; aggrecan epidermal growth factor-like domain-1; aggrecan interglobular domain; aggrecan, structural proteoglycan of cartilage; b2b183Clo; BOS_20116; cartilage aggregating proteoglycan; Cartilage-specific proteoglycan core protein; Chondroitin sulfate proteoglycan 1; Chondroitin sulfate proteoglycan core protein 1; cmd; CSPCP; CSPG1; CSPGCP; large aggregating proteoglycan; large aggregating proteoglycan, antigen; MSK16; SEDK

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

176

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P16112

Gene Symbols

ACAN

Immunogen

KLH conjugated synthetic peptide derived from Human Aggrecan.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Aggrecan also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1 is a protein that is encoded by the ACAN gene
  • The encoded protein is an integral part of the extracellular matrix in cartilaginous tissue and it withstands compression in cartilage
  • The human form of the protein is 2316 amino acids long (approximately 250 kDa) and can be expressed in multiple isoforms due to alternative splicing
  • Aggrecan exhibits a bottlebrush structure, in which chondroitin sulfate and keratan sulfate chains are attached to an extended protein core
  • The synthesis and degradation of aggrecan are being investigated for their roles in cartilage deterioration during joint injury, disease, and aging
  • It contains three interglobular domains (IGDs), G1, G2, and G3 that are involved in aggregation, hyaluronan binding, cell adhesion, and chondrocyte apoptosis
  • Aggrecan fragments from articular cartilage are released into the synovial fluid at all stages of human osteoarthritis as a result of cleavage by aggrecanase and MMP activity
  • Antibodies BC-3 and BC-4 can be used to detect these neo epitopes of Aggrecanase (ARGSVXXX) and MMP (XXXVDIPEN), respectively.

Compare Similar Items

Show Difference

Img

Bioss

50-198-1557

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Antigen:
Aggrecan

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ACAN

Gene Alias:
Acan; Agc; AGC1; AGCAN; aggrecan; aggrecan 1; aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122); Aggrecan core protein; Aggrecan core protein 2; aggrecan epidermal growth factor-like domain-1; aggrecan interglobular domain; aggrecan, structural proteoglycan of cartilage; b2b183Clo; BOS_20116; cartilage aggregating proteoglycan; Cartilage-specific proteoglycan core protein; Chondroitin sulfate proteoglycan 1; Chondroitin sulfate proteoglycan core protein 1; cmd; CSPCP; CSPG1; CSPGCP; large aggregating proteoglycan; large aggregating proteoglycan, antigen; MSK16; SEDK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
176

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P16112

Gene Symbols:
ACAN

Immunogen:
KLH conjugated synthetic peptide derived from Human Aggrecan.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1558

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Antigen:
DOCK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dock3

Gene Alias:
dedicator of cytokinesis 3; dedicator of cyto-kinesis 3; Dedicator of cytokinesis protein 3; DOCK3; KIAA0299; mKIAA0299; MOCA; Modifier of cell adhesion; PBP; Presenilin-binding protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1795

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q8IZD9

Gene Symbols:
Dock3

Immunogen:
KLH conjugated synthetic peptide derived from human DOCK3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1560

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Antigen:
Beta catenin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CTNNB1

Gene Alias:
armadillo; Bcatenin; B-catenin; beta catenin; Betacatenin; Beta-catenin; beta-catenin 1; Bfc; BOS_20731; C20orf33; catenin; catenin (cadherin associated protein), beta 1; catenin (cadherin associated protein), beta 1, 88kDa; catenin (cadherin-associated protein) beta 1; catenin (cadherin-associated protein), beta 1; catenin (cadherin-associated protein), beta 1, 88kDa; Catenin b 1; Catenin b1; catenin beta; catenin beta 1; catenin beta 1 L homeolog; Catenin beta1; Catenin beta-1; Catenin ß 1; Catenin ß1; Catnb; CHBCAT; CTNB1; CTNNB; Ctnnb1; ctnnb1.L; ctnnb1-a; ctnnb1-b; dJ633O20.1; DKFZp686D02253; FLJ25606; FLJ37923; id:ibd2058; Mesc; MRD19; NAP; NYD-SP19; OK/SW-cl.35; OTTHUMP00000209289; P14L; PP8304; PRO2286; RP5-1118M15.1; wu:fb73e10; wu:fi81c06; wu:fk25h01; XELAEV_18031149mg; ß catenin; ßcatenin

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1499

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P35222

Gene Symbols:
CTNNB1

Immunogen:
KLH conjugated synthetic peptide derived from human Beta catenin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1565

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Antigen:
PICALM/CALM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Picalm

Gene Alias:
CALM; Clathrin assembly lymphoid myeloid leukemia; Clathrin assembly lymphoid myeloid leukemia protein; clathrin-assembly lymphoid leukemia protein; clathrin-assembly lymphoid myeloid leukemia protein; CLTH; Fit1; fit-1; LAP; mKIAA4114; PAP180; phosphatidylinositol binding clathrin assembly protein; Phosphatidylinositol-binding clathrin assembly protein; PICALM; rCALM

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8301

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q13492

Gene Symbols:
Picalm

Immunogen:
KLH conjugated synthetic peptide derived from human PICALM/CALM.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG