50-198-1588
Senataxin/SETX Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-1588-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-1588 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
Senataxin/SETX
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SETX
Gene Alias
ALS4; Amyotrophic lateral sclerosis 4 protein; AOA2; bA479K20.2; KIAA0625; Probable helicase senataxin; SCAR1; SEN1 homolog; Senataxin; SETX
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
23064
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q7Z333
Gene Symbols
SETX
Immunogen
KLH conjugated synthetic peptide derived from human Senataxin .
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Probable RNA/DNA helicase involved in diverse aspects of RNA metabolism and genomic integrity
- Plays a role in transcription regulation by its ability to modulate RNA Polymerase II (Pol II) binding to chromatin and through its interaction with proteins involved in transcription (PubMed:19515850, PubMed:21700224)
- Contributes to the mRNA splicing efficiency and splice site selection (PubMed:19515850)
- Required for the resolution of R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site, allowing XRN2 recruitment and XRN2-mediated degradation of the downstream cleaved RNA and hence efficient RNA polymerase II (RNAp II) transcription termination (PubMed:19515850, PubMed:21700224, PubMed:26700805)
- Required for the 3′ transcriptional termination of PER1 and CRY2, thus playing an important role in the circadian rhythm regulation
- Involved in DNA double-strand breaks damage response generated by oxidative stress (PubMed:17562789)
- In association with RRP45, targets the RNA exosome complex to sites of transcription-induced DNA damage (PubMed:24105744)
- Plays a role in the development and maturation of germ cells: essential for male meiosis, acting at the interface of transcription and meiotic recombination, and in the process of gene silencing during meiotic sex chromosome inactivation (MSCI)
- May be involved in telomeric stability through the regulation of telomere repeat-containing RNA (TERRA) transcription (PubMed:21112256)
- Plays a role in neurite outgrowth in hippocampal cells through FGF8-activated signaling pathways
- Inhibits retinoic acid-induced apoptosis (PubMed:21576111).
Compare Similar Items
Show Difference
Antigen: Senataxin/SETX
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SETX
Gene Alias: ALS4; Amyotrophic lateral sclerosis 4 protein; AOA2; bA479K20.2; KIAA0625; Probable helicase senataxin; SCAR1; SEN1 homolog; Senataxin; SETX
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23064
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q7Z333
Gene Symbols: SETX
Immunogen: KLH conjugated synthetic peptide derived from human Senataxin .
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Senataxin/SETX
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SETX
Gene Alias:
ALS4; Amyotrophic lateral sclerosis 4 protein; AOA2; bA479K20.2; KIAA0625; Probable helicase senataxin; SCAR1; SEN1 homolog; Senataxin; SETX
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23064
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q7Z333
Gene Symbols:
SETX
Immunogen:
KLH conjugated synthetic peptide derived from human Senataxin .
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TMEM106B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMEM106B
Gene Alias: 2310036D22Rik; 5830455K21Rik; 6430519M21Rik; AI428776; AI661344; BOS_4052; LOC100356191; LRRGT00101; Tmem106b; tmem106bb; Transmembrane protein 106B; transmembrane protein 106Bb; transmembrane protein 106C-like; zgc:114147
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 54664
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q9NUM4
Gene Symbols: TMEM106B
Immunogen: KLH conjugated synthetic peptide derived from human TMEM106B .
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TMEM106B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMEM106B
Gene Alias:
2310036D22Rik; 5830455K21Rik; 6430519M21Rik; AI428776; AI661344; BOS_4052; LOC100356191; LRRGT00101; Tmem106b; tmem106bb; Transmembrane protein 106B; transmembrane protein 106Bb; transmembrane protein 106C-like; zgc:114147
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
54664
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q9NUM4
Gene Symbols:
TMEM106B
Immunogen:
KLH conjugated synthetic peptide derived from human TMEM106B .
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: HAAO
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HAAO
Gene Alias: 0610007K21Rik; 0610012J07Rik; 3HAO; 3-HAO; 3-HAO {ECO:0000255; 3-HAOxase; 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate 3,4-dioxygenase {ECO:0000255; 3-hydroxyanthranilate oxygenase; 3-hydroxyanthranilate oxygenase {ECO:0000255; 3-hydroxyanthranilic acid dioxygenase; 3-hydroxyanthranilic acid dioxygenase {ECO:0000255; Haao; HAD; HAD {ECO:0000255; HAMAP-Rule:MF_03019}; HAO
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23498
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P46952
Gene Symbols: HAAO
Immunogen: KLH conjugated synthetic peptide derived from human HAAO.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HAAO
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HAAO
Gene Alias:
0610007K21Rik; 0610012J07Rik; 3HAO; 3-HAO; 3-HAO {ECO:0000255; 3-HAOxase; 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate 3,4-dioxygenase {ECO:0000255; 3-hydroxyanthranilate oxygenase; 3-hydroxyanthranilate oxygenase {ECO:0000255; 3-hydroxyanthranilic acid dioxygenase; 3-hydroxyanthranilic acid dioxygenase {ECO:0000255; Haao; HAD; HAD {ECO:0000255; HAMAP-Rule:MF_03019}; HAO
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23498
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P46952
Gene Symbols:
HAAO
Immunogen:
KLH conjugated synthetic peptide derived from human HAAO.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: HAP40/F8a
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Gene Alias: AI852759; cpG island protein; DXUcsf1; F8a; F8a1; factor 8-associated gene A; Factor VIII associated protein; factor VIII intron 22 protein; RP23-114O19.4
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: __
Gene Symbols: __
Immunogen: KLH conjugated synthetic peptide derived from human HAP40.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HAP40/F8a
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
AI852759; cpG island protein; DXUcsf1; F8a; F8a1; factor 8-associated gene A; Factor VIII associated protein; factor VIII intron 22 protein; RP23-114O19.4
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
KLH conjugated synthetic peptide derived from human HAP40.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG