50-198-1753

MEIS1 + MEIS2 Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-1753-Each-of-1 In Stock ₹ 36,897.75

50-198-1753 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

MEIS1 + MEIS2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MEIS1

Gene Symbols

MEIS1, MEIS2

Immunogen

KLH conjugated synthetic peptide derived from human MEIS2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O00470, O14770, P97367, Q60954

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

17268, 17536, 311311, 4211, 4212, 686117

Content And Storage

-20°C

Form

Liquid

Related Products

Img

Bioss

50-198-7761

--

Img

Bioss

50-198-1759

--

Img

Bioss

50-198-8994

--

Img

Bioss

50-198-1745

--

Img

Bioss

50-198-4881

--

Img

Bioss

50-198-2128

--

Img

Bioss

50-198-1749

--

Img

Bioss

50-198-8631

--

Description

  • MEIS1 acts as a transcriptional regulator of PAX6
  • Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2
  • Required for hematopoiesis, megakaryocyte lineage development and vascular patterning
  • May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias
  • MEIS2 is involved in transcriptional regulation
  • Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabilization of the homeoprotein-DNA complex
  • Isoform 3 is required for the activity of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element; MEIS2 is not involved in complex DNA-binding
  • Probably in complex with PBX1, is involved in transcriptional regulation by KLF4
  • Isoform 3 and isoform 4 can bind to a EPHA8 promoter sequence containing the DNA motif 5′-CGGTCA-3′; in cooperation with a PBX protein (such as PBX2) is proposed to be involved in the transcriptional activation of EPHA8 in the developing midbrain
  • May be involved in regulation of myeloid differentiation
  • Can bind to the DNA sequence 5′-TGACAG-3′in the activator ACT sequence of the D(1A) dopamine receptor (DRD1) promoter and activate DRD1 transcription; isoform 5 cannot activate DRD1 transcription.

Compare Similar Items

Show Difference

Img

Bioss

50-198-1753

--


Antigen:
MEIS1 + MEIS2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MEIS1

Gene Symbols:
MEIS1, MEIS2

Immunogen:
KLH conjugated synthetic peptide derived from human MEIS2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O00470, O14770, P97367, Q60954

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17268, 17536, 311311, 4211, 4212, 686117

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-1754

--


Antigen:
METRN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
METRN

Gene Symbols:
METRN

Immunogen:
KLH conjugated synthetic peptide derived from human METRN.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9UJH8

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
79006

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-1755

--


Antigen:
MPP5/PALS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MPP5

Gene Symbols:
MPP5

Immunogen:
KLH conjugated synthetic peptide derived from human MPP5/PALS1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q8N3R9

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
64398

Content And Storage:
-20°C

Form:
Liquid

Img

Bioss

50-198-1757

--


Antigen:
Meis homeobox 3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MEIS3

Gene Symbols:
MEIS3

Immunogen:
KLH conjugated synthetic peptide derived from human Meis homeobox 3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q99687

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
56917

Content And Storage:
-20°C

Form:
Liquid