50-198-1772

NOTUM Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-1772-Each-of-1 In Stock ₹ 36,897.75

50-198-1772 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

NOTUM

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NOTUM

Gene Alias

[Wnt protein] O-palmitoleoyl-L-serine hydrolase; 5730593N15Rik; hNOTUM; Notum; notum pectinacetylesterase homolog; notum pectinacetylesterase homolog (Drosophila); NOTUM, palmitoleoyl-protein carboxylesterase; OK/SW-CL.30; Palmitoleoyl-protein carboxylesterase NOTUM; protein notum homolog; RGD1307119

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

147111

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q6P988

Gene Symbols

NOTUM

Immunogen

KLH conjugated synthetic peptide derived from human NOTUM.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Genetic studies in Drosophila have revealed a novel secreted antagonist for Wingless (Wg) signaling, referred to as Notum/Wingful (Wf)
  • Wf/Notum encodes a protein of 430 amino acid residues, which is related to plant pectin acetylesterases of the a/beta-hydrolase superfamily
  • The main target of Notum action appears to be cell surface proteoglycans Dally and/or Dally-like (Dlp)
  • Notum governs the extracellular Wg morphogen distribution via Dally and Dlp
  • Also, like some vertebrate Wnt antagonists, notum expression is activated by Wg signaling, revealing the existence of a feedback control mechanism in which Wg modifies its own gradient distribution
  • In vertebrate, proteoglycans related to Dally and Dlp likely play important roles in Wnt signaling which encodes a glypican that is required for Wnt-11 signaling
  • A single ortholog of Notum exists in the mouse and the human genome, implying that a similar regulatory mechanism may exist in vertebrates.

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Bioss

50-198-1772

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Antigen:
NOTUM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOTUM

Gene Alias:
[Wnt protein] O-palmitoleoyl-L-serine hydrolase; 5730593N15Rik; hNOTUM; Notum; notum pectinacetylesterase homolog; notum pectinacetylesterase homolog (Drosophila); NOTUM, palmitoleoyl-protein carboxylesterase; OK/SW-CL.30; Palmitoleoyl-protein carboxylesterase NOTUM; protein notum homolog; RGD1307119

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
147111

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q6P988

Gene Symbols:
NOTUM

Immunogen:
KLH conjugated synthetic peptide derived from human NOTUM.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1774

--


Antigen:
ABCA12

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABCA12

Gene Alias:
4832428G11Rik; 4833417A11Rik; ABC12; ABCA12; ARCI4A; ARCI4B; ATP binding cassette subfamily A member 12; ATP-binding cassette 12; ATP-binding cassette sub-family A member 12; ATP-binding cassette transporter 12; ATP-binding cassette, subfamily A (ABC1), member 12; ATP-binding cassette, sub-family A (ABC1), member 12; ATP-binding cassette, sub-family A, member 12; BOS_2060; DKFZp434G232; FLJ41584; ICR2B; LI2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
26154

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q86UK0

Gene Symbols:
ABCA12

Immunogen:
KLH conjugated synthetic peptide derived from human ABCA12.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1775

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Antigen:
ABCB9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABCB9

Gene Alias:
ABC transporter 9 protein; ABCB9; ATP binding cassette subfamily B member 9; ATP-binding cassette sub-family B member 9; ATP-binding cassette transporter 9; ATP-binding cassette, subfamily B (MDR/TAP), member 9; ATP-binding cassette, sub-family B (MDR/TAP), member 9; ATP-binding cassette, sub-family B, member 9; BOS_16586; EST122234; KIAA1520; mABCB9; mKIAA1520; TAPL; TAP-like ABC transporter; TAP-like protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23457

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9NP78

Gene Symbols:
ABCB9

Immunogen:
KLH conjugated synthetic peptide derived from human ABCB9.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-1777

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Antigen:
ECE1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ECE1

Gene Alias:
AW322500; ECE; ECE 1; Ece1; ECE-1; ECE-1a; ECE-1b; ECE-1d; endothelin converting enzyme 1; Endothelin-converting enzyme 1; endothelin-converting enzyme-1a; endothelin-converting enzyme-1b; endothelin-converting enzyme-1d

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1889

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P42892

Gene Symbols:
ECE1

Immunogen:
KLH conjugated synthetic peptide derived from human ECE1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG