50-198-2065

Aggrecan core protein 1 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Each of 1 50-198-2065-Each-of-1 In Stock ₹ 36,897.75

50-198-2065 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Aggrecan core protein 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ACAN

Gene Alias

Acan; Agc; AGC1; AGCAN; aggrecan; aggrecan 1; aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122); Aggrecan core protein; Aggrecan core protein 2; aggrecan epidermal growth factor-like domain-1; aggrecan interglobular domain; aggrecan, structural proteoglycan of cartilage; b2b183Clo; BOS_20116; cartilage aggregating proteoglycan; Cartilage-specific proteoglycan core protein; Chondroitin sulfate proteoglycan 1; Chondroitin sulfate proteoglycan core protein 1; cmd; CSPCP; CSPG1; CSPGCP; large aggregating proteoglycan; large aggregating proteoglycan, antigen; MSK16; SEDK

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

176

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P16112

Gene Symbols

ACAN

Immunogen

KLH conjugated synthetic peptide derived from human Aggrecan core protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Aggrecan also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1 is a protein that is encoded by the ACAN gene
  • The encoded protein is an integral part of the extracellular matrix in cartilaginous tissue and it withstands compression in cartilage
  • The human form of the protein is 2316 amino acids long (approximately 250 kDa) and can be expressed in multiple isoforms due to alternative splicing
  • Aggrecan exhibits a bottlebrush structure, in which chondroitin sulfate and keratan sulfate chains are attached to an extended protein core
  • The synthesis and degradation of aggrecan are being investigated for their roles in cartilage deterioration during joint injury, disease, and aging
  • It contains three interglobular domains (IGDs), G1, G2, and G3 that are involved in aggregation, hyaluronan binding, cell adhesion, and chondrocyte apoptosis
  • Aggrecan fragments from articular cartilage are released into the synovial fluid at all stages of human osteoarthritis as a result of cleavage by aggrecanase and MMP activity
  • Antibodies BC-3 and BC-4 can be used to detect these neo epitopes of Aggrecanase (ARGSVXXX) and MMP (XXXVDIPEN), respectively.

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Bioss

50-198-2065

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Antigen:
Aggrecan core protein 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ACAN

Gene Alias:
Acan; Agc; AGC1; AGCAN; aggrecan; aggrecan 1; aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122); Aggrecan core protein; Aggrecan core protein 2; aggrecan epidermal growth factor-like domain-1; aggrecan interglobular domain; aggrecan, structural proteoglycan of cartilage; b2b183Clo; BOS_20116; cartilage aggregating proteoglycan; Cartilage-specific proteoglycan core protein; Chondroitin sulfate proteoglycan 1; Chondroitin sulfate proteoglycan core protein 1; cmd; CSPCP; CSPG1; CSPGCP; large aggregating proteoglycan; large aggregating proteoglycan, antigen; MSK16; SEDK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
176

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P16112

Gene Symbols:
ACAN

Immunogen:
KLH conjugated synthetic peptide derived from human Aggrecan core protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-2067

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Antigen:
ZNF704

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF704

Gene Alias:
Gig1; Zinc finger protein 704; ZNF704

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
619279

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q6ZNC4

Gene Symbols:
ZNF704

Immunogen:
KLH conjugated synthetic peptide derived from human ZNF704.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-2068

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Antigen:
ZFP100/ZNF473

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF473

Gene Alias:
HZFP100; KIAA1141; ZFP100; Zfp-100; Zinc finger protein 100 homolog; Zinc finger protein 473; ZN473; ZNF473

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
25888

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q8WTR7

Gene Symbols:
ZNF473

Immunogen:
KLH conjugated synthetic peptide derived from human ZFP100/ZNF473.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-2071

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Antigen:
DAZL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DAZL

Gene Alias:
BOS_1495; DAZ homolog; DAZH; Dazl; Dazl1; Dazla; Daz-like; DAZ-like autosomal; deleted in azoospermia like; deleted in azoospermia protein 3; Deleted in azoospermia-like; Deleted in azoospermia-like 1; deleted in azoospermia-like protein; germline specific RNA binding protein; HGNC:2685; MGC26406; spermatogenesis gene on the Y-like autosomal; SPGYLA; SPGY-like-autosomal; testis secretory sperm-binding protein Li 204a; Tpx2; Tpx-2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1618

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q92904

Gene Symbols:
DAZL

Immunogen:
KLH conjugated synthetic peptide derived from human DAZL.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG