50-198-2202

TLE5/Amino-terminal enhancer of split Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-2202-Each-of-1 In Stock ₹ 36,897.75

50-198-2202 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

TLE5/Amino-terminal enhancer of split

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TLE5

Gene Alias

AES; AES-1; AES-2; AL024115; Amino enhancer of split; Amino-terminal enhancer of split; Esp1; Gp130-associated protein GAM; Grg; GRG5; Grg-5; Groucho-related protein 5; Protein ESP1; Protein GRG; related to Drosophila groucho; R-esp1; TLE family member 5; TLE family member 5, transcriptional modulator; TLE5

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

166

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q08117

Gene Symbols

TLE5

Immunogen

KLH conjugated synthetic peptide derived from human TLE5/Amino-terminal enhancer of split.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading
  • Anoikis is the molecular mechanism of apop-tosis induced by integrin detachment
  • Amino-terminal enhancer of split (AES) is a member of the Groucho/ transducin-like enhancer of split (TLE) family of transcriptional regulators, a group of transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination
  • AES forms a complex with Bit1 (Bcl-2 inhibitor of transcription 1), a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis
  • It has been suggested that this complex turns off a survival-promoting gene transcription program controlled by the TLE protein family
  • Interestingly, apoptosis of cells transfected with AES and Bit1 could be inhibited if the cells were allowed to attach to fibronectin through the alpha5beta1 integrin suggesting that the Bit1-AES pathway contributing to anoikis is regulated by integrins, and in particular, the alpha5beta1 integrin.

Compare Similar Items

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Img

Bioss

50-198-2202

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Antigen:
TLE5/Amino-terminal enhancer of split

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TLE5

Gene Alias:
AES; AES-1; AES-2; AL024115; Amino enhancer of split; Amino-terminal enhancer of split; Esp1; Gp130-associated protein GAM; Grg; GRG5; Grg-5; Groucho-related protein 5; Protein ESP1; Protein GRG; related to Drosophila groucho; R-esp1; TLE family member 5; TLE family member 5, transcriptional modulator; TLE5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
166

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q08117

Gene Symbols:
TLE5

Immunogen:
KLH conjugated synthetic peptide derived from human TLE5/Amino-terminal enhancer of split.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-2203

--


Antigen:
BCL9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCL9

Gene Alias:
2610202E01Rik; 8030475K17Rik; A330041G23Rik; B cell CLL/lymphoma 9; B-cell CLL/lymphoma 9; B-cell CLL/lymphoma 9 protein; B-cell lymphoma 9 protein; Bcl9; bcl-9; Gm130; LGS; nuclear co-factor of beta-catenin signalling; Protein legless homolog

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
607

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O00512

Gene Symbols:
BCL9

Immunogen:
KLH conjugated synthetic peptide derived from human BCL9.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-2204

--


Antigen:
DTX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DTX2

Gene Alias:
2610524D08Rik; AA408415; AU022494; deltex 2 homolog; deltex 2 homolog (Drosophila); deltex 2, E3 ubiquitin ligase; deltex E3 ubiquitin ligase 2; deltex homolog 2; Deltex2; Dtx2; hDTX2; KIAA1528; mDTX2; Probable E3 ubiquitin-protein ligase DTX2; Protein deltex-2; RING finger protein 58; RING-type E3 ubiquitin transferase DTX2; RNF58; zinc ion binding protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
113878

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q86UW9

Gene Symbols:
DTX2

Immunogen:
KLH conjugated synthetic peptide derived from human DTX2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-2207

--


Antigen:
MUC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MUC1

Gene Alias:
ADMCKD; ADMCKD1; Breast carcinoma-associated antigen DF3; CA 15-3; Cancer antigen 15-3; Carcinoma-associated mucin; CD227; DF3 antigen; EMA; Episialin; H23 antigen; H23AG; J19; KL-6; Krebs von den Lungen-6; MAM6; MCD; MCKD; MCKD1; Medullary cystic kidney disease, autosomal dominant; Muc1; Muc-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; mucin 1, cell surface associated; mucin 1, transmembrane; Mucin1; Mucin-1; Mucin-1 subunit alpha; Mucin-1 subunit beta; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; tumor associated epithelial mucin; Tumor-associated epithelial membrane antigen; Tumor-associated mucin

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4582

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P15941

Gene Symbols:
MUC1

Immunogen:
KLH conjugated synthetic peptide derived from human MUC1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG