50-198-2284

APOBEC3C Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-2284-Each-of-1 In Stock ₹ 36,897.75

50-198-2284 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

APOBEC3C

Classification

Polyclonal

Conjugate

Unconjugated

Gene

APOBEC3C

Gene Alias

A3C; APOBEC1L; APOBEC1-like; APOBEC3C; apolipoprotein B editing enzyme catalytic polypeptide-like 3C; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; ARDC2; ARDC4; ARP5; bK150C2.3; DNA dC->dU-editing enzyme APOBEC-3C; MGC19485; PBI; Phorbolin I; probable DNA dC->dU-editing enzyme APOBEC-3C

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

27350

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q9NRW3

Gene Symbols

APOBEC3C

Immunogen

KLH conjugated synthetic peptide derived from human APOBEC3C.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • APOBEC (apolipoprotein B mRNA editing enzyme, catalytic) proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA
  • The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22
  • Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA
  • Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses
  • Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome
  • Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication
  • This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.

Compare Similar Items

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Bioss

50-198-2284

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Antigen:
APOBEC3C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOBEC3C

Gene Alias:
A3C; APOBEC1L; APOBEC1-like; APOBEC3C; apolipoprotein B editing enzyme catalytic polypeptide-like 3C; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C; apolipoprotein B mRNA editing enzyme catalytic subunit 3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; ARDC2; ARDC4; ARP5; bK150C2.3; DNA dC->dU-editing enzyme APOBEC-3C; MGC19485; PBI; Phorbolin I; probable DNA dC->dU-editing enzyme APOBEC-3C

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
27350

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9NRW3

Gene Symbols:
APOBEC3C

Immunogen:
KLH conjugated synthetic peptide derived from human APOBEC3C.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-2285

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Antigen:
APOC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOC2

Gene Alias:
APC 2; APC2; APO C2; Apo CII; APOC 2; ApoC II; APOC2; APOC2 protein; ApoCII; Apo-CII; APOC-II; Apolipoprotein C II; Apolipoprotein C2; Apolipoprotein CII; Apolipoprotein C-II; ApolipoproteinCII; MGC75082; ProapoC-II; Proapolipoprotein C-II; RGD1560725

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
344

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P02655

Gene Symbols:
APOC2

Immunogen:
KLH conjugated synthetic peptide derived from human Apolipoprotein CII/APOC2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-2286

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Antigen:
APOL1/Apolipoprotein L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOL1

Gene Alias:
APOL; Apo-L; APOL- I; APOL1; ApoL-I; Apolipoprotein L; apolipoprotein L 1; apolipoprotein L, 1; Apolipoprotein L1; Apolipoprotein L-I; FSGS4; OTTHUMP00000028705

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
8542

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O14791

Gene Symbols:
APOL1

Immunogen:
KLH conjugated synthetic peptide derived from human APOL1/Apolipoprotein L.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-2288

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Antigen:
APOL5/Apolipoprotein L5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOL5

Gene Alias:
APOL5; apolipoprotein L, 5; Apolipoprotein L5; Apolipoprotein L-V; APOLV; ApoL-V; OTTHUMP00000028773

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
80831

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9BWW9

Gene Symbols:
APOL5

Immunogen:
KLH conjugated synthetic peptide derived from human APOL5/Apolipoprotein L5.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG