50-198-2327

ATF6 beta Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Each of 1 50-198-2327-Each-of-1 In Stock ₹ 36,897.75

50-198-2327 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

ATF6 beta

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATF6B

Gene Alias

9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; Activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; ATF6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; ATF6B; ATF6beta; ATF6-beta; BOS_21614; BOS_2657; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; CREBL1; Creb-related protein; Creb-rp; Cyclic AMP-dependent transcription factor ATF-6 alpha; Cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1388, 22926

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P18850, Q99941

Gene Symbols

ATF6, ATF6B

Immunogen

KLH conjugated synthetic peptide derived from human ATF6 beta.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • ATF6 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes
  • It binds DNA on the 5′-CCAC[GA]-3′half of the ER stress response element (ERSE) (5′-CCAAT-N(9)-CCAC[GA]-3′) and of ERSE II (5′-ATTGG-N-CCACG-3′)
  • Binding to ERSE requires binding of NF-Y to ERSE
  • ATF6 could also be involved in activation of transcription by the serum response factor
  • ATF6 exists as a homodimer and heterodimer with ATF6 beta
  • The dimer interacts with the nuclear transcription factor Y (NF-Y) trimer through direct binding to NF-Y subunit C (NF-YC)
  • It Interacts also with the transcription factors GTF2I, YY1 and SRF
  • Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus
  • The basic domain of ATF6 functions as a nuclear localization signal and the basic leucine-zipper domain is sufficient for association with the NF-Y trimer and binding to ERSE
  • During the unfolded protein response an approximately 50 kDa fragment containing the cytoplasmic transcription factor domain is released by proteolysis
  • The cleavage seems to be performed sequentially by site-1 and site-2 proteases
  • ATF6 is N-glycosylated, phosphorylated in vitro by MAPK14/P38MAPK and belongs to the bZIP family.

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Bioss

50-198-2327

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Antigen:
ATF6 beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATF6B

Gene Alias:
9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; Activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; ATF6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; ATF6B; ATF6beta; ATF6-beta; BOS_21614; BOS_2657; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; CREBL1; Creb-related protein; Creb-rp; Cyclic AMP-dependent transcription factor ATF-6 alpha; Cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1388, 22926

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P18850, Q99941

Gene Symbols:
ATF6, ATF6B

Immunogen:
KLH conjugated synthetic peptide derived from human ATF6 beta.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-2328

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Antigen:
ATIC/AICAR transformylase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATIC

Gene Alias:
2610509C24Rik; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase L homeolog; 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase; AA536954; AICAR; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICAR transformylase; AICARFT; AICARFT/IMPCHASE; ATIC; atic.L; AW212393; Bifunctional purine biosynthesis protein PURH; Bifunctional purine biosynthesis protein PURH, N-terminally processed; epididymis secretory sperm binding protein Li 70p; HEL-S-70p; IMP cyclohydrolase; IMP synthase; IMPCHASE; Inosinicase; OK/SW-cl.86; Phosphoribosylaminoimidazolecarboxamide formyltransferase; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PURH; XELAEV_18044849mg

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
471

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P31939

Gene Symbols:
ATIC

Immunogen:
KLH conjugated synthetic peptide derived from human ATIC/AICAR transformylase.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-2331

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Antigen:
ATP5G2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATP5MC2

Gene Alias:
1810041M08Rik; ATP synthase c subunit; ATP synthase F(0) complex subunit C2, mitochondrial; ATP synthase lipid-binding protein; ATP synthase lipid-binding protein, mitochondrial; ATP synthase membrane subunit c locus 2; ATP synthase proteolipid P2; ATP synthase proton-transporting mitochondrial F(0) complex subunit C2; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9); ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9); ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9); ATP5A; ATP5G2; Atp5mc2; ATPase protein 9; ATPase subunit c; mitochondrial ATP synthase, subunit C (subunit 9), isoform 2; PSEC0033

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
517

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q06055

Gene Symbols:
ATP5MC2

Immunogen:
KLH conjugated synthetic peptide derived from human ATP5G2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-2332

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Antigen:
ATP6V0D2/V-ATPase D2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATP6V0D2

Gene Alias:
1620401A02Rik; AI324824; ATP6D2; Atp6v0d2; ATPase H+ transporting V0 subunit d2; ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2; ATPase, H+ transporting, lysosomal V0 subunit D2; ATPase, H+ transporting, lysosomal, V0 subunit d1-like; ATPase, H+ transporting, V0 subunit D, isoform 2; BOS_14095; FLJ38708; LOC100350237; Osteoclast-specific vacuolar ATP synthase; Vacuolar proton pump subunit d 2; vacuolar proton-translocating ATPase d subunit d2; V-ATPase; V-ATPase subunit d 2; VMA6; V-type proton ATPase subunit d 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
245972

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q8N8Y2

Gene Symbols:
ATP6V0D2

Immunogen:
KLH conjugated synthetic peptide derived from human ATP6V0D2/V-ATPase D2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG