50-198-2442
NFKBIA/IKB alpha Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-2442-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-2442 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
NFKBIA/IKB alpha
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NFKBIA
Gene Alias
AI462015; BOS_20329; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; ikappaBalpha; I-kappaBalpha; I-kappa-B-alpha; IKBA; IKBalpha; IkB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; NFKBIA; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
4792
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P25963
Gene Symbols
NFKBIA
Immunogen
KLH conjugated synthetic peptide derived from mouse IKB alpha.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity
- The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol
- The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus
- A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha
- These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses
- In humans, the gene is located on the q arm of chromosome 14
- Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB
- IkB kinase alpha (IKK alpha), previously designated CHUK, interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation Serines 32 and 36
- IKK alpha appears to be critical for NFkB activation in response to proinflammatory cytokines
- Phosphorylation of IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1
- The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma, and each appear to make essential contributions to IkB phosphorylation.
Compare Similar Items
Show Difference
Antigen: NFKBIA/IKB alpha
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NFKBIA
Gene Alias: AI462015; BOS_20329; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; ikappaBalpha; I-kappaBalpha; I-kappa-B-alpha; IKBA; IKBalpha; IkB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; NFKBIA; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4792
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P25963
Gene Symbols: NFKBIA
Immunogen: KLH conjugated synthetic peptide derived from mouse IKB alpha.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NFKBIA/IKB alpha
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NFKBIA
Gene Alias:
AI462015; BOS_20329; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; ikappaBalpha; I-kappaBalpha; I-kappa-B-alpha; IKBA; IKBalpha; IkB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; NFKBIA; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4792
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P25963
Gene Symbols:
NFKBIA
Immunogen:
KLH conjugated synthetic peptide derived from mouse IKB alpha.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: BOULE
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BOLL
Gene Alias: 4930554P13Rik; 4930597B14Rik; bol, boule-like; bol, boule-like (Drosophila); BOLL; BOS_1970; Boule; boule homolog, RNA binding protein; boule-like; boule-like RNA binding protein; boule-like RNA-binding protein; LOC100341687; Protein boule-like; RGD1559527
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 66037
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q8N9W6
Gene Symbols: BOLL
Immunogen: KLH conjugated synthetic peptide derived from human BOULE.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
BOULE
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BOLL
Gene Alias:
4930554P13Rik; 4930597B14Rik; bol, boule-like; bol, boule-like (Drosophila); BOLL; BOS_1970; Boule; boule homolog, RNA binding protein; boule-like; boule-like RNA binding protein; boule-like RNA-binding protein; LOC100341687; Protein boule-like; RGD1559527
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
66037
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q8N9W6
Gene Symbols:
BOLL
Immunogen:
KLH conjugated synthetic peptide derived from human BOULE.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: BPY2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BPY2C
Gene Alias: Basic charge, Y-linked 2; basic charge, Y-linked, 2; basic charge, Y-linked, 2C; basic protein on Y chromosome 2; BPY2; BPY2A; BPY2B; BPY2C; testis-specific basic protein on Y, 2; Testis-specific basic protein Y 2; variable charge, Y-linked, 2; Variably charged protein Y 2; VCY2; VCY2A; VCY2B; VCY2C
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 442868, 9083
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: O14599
Gene Symbols: BPY2, BPY2C
Immunogen: KLH conjugated synthetic peptide derived from human BPY2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
BPY2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BPY2C
Gene Alias:
Basic charge, Y-linked 2; basic charge, Y-linked, 2; basic charge, Y-linked, 2C; basic protein on Y chromosome 2; BPY2; BPY2A; BPY2B; BPY2C; testis-specific basic protein on Y, 2; Testis-specific basic protein Y 2; variable charge, Y-linked, 2; Variably charged protein Y 2; VCY2; VCY2A; VCY2B; VCY2C
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
442868, 9083
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
O14599
Gene Symbols:
BPY2, BPY2C
Immunogen:
KLH conjugated synthetic peptide derived from human BPY2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: BRAF35
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HMG20B
Gene Alias: AW610687; BOS_7747; BRAF25; BRAF35; BRCA2-associated factor 35; fc85b02; FLJ26127; high mobility group 20 B; high mobility group 20B; high mobility group box domain containing; high mobility group protein 20 B; high-mobility group 20B; HMG box domain containing 2; HMG box-containing protein 20B; HMG domain-containing protein 2; HMG domain-containing protein HMGX2; Hmg20b; Hmgx2; HMGXB2; hypothetical protein LOC553572; PP7706; pp8857; si:dkey-110c1.6; SMARCE1R; SMARCE1-related protein; SOXL; Sox-like transcriptional factor; Structural DNA-binding protein BRAF35; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1-related; wu:fc85b02; zgc:110001
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 10362
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q9P0W2
Gene Symbols: HMG20B
Immunogen: KLH conjugated synthetic peptide derived from human BRAF35.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
BRAF35
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HMG20B
Gene Alias:
AW610687; BOS_7747; BRAF25; BRAF35; BRCA2-associated factor 35; fc85b02; FLJ26127; high mobility group 20 B; high mobility group 20B; high mobility group box domain containing; high mobility group protein 20 B; high-mobility group 20B; HMG box domain containing 2; HMG box-containing protein 20B; HMG domain-containing protein 2; HMG domain-containing protein HMGX2; Hmg20b; Hmgx2; HMGXB2; hypothetical protein LOC553572; PP7706; pp8857; si:dkey-110c1.6; SMARCE1R; SMARCE1-related protein; SOXL; Sox-like transcriptional factor; Structural DNA-binding protein BRAF35; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1-related; wu:fc85b02; zgc:110001
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
10362
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q9P0W2
Gene Symbols:
HMG20B
Immunogen:
KLH conjugated synthetic peptide derived from human BRAF35.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG