50-198-2788
GCAP1 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-2788-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-2788 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
GCAP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Guca1a
Gene Alias
BOS_21468; C6orf131; COD3; cone dystrophy 3; CORD14; GC-A; GCAP; GCAP 1; Gcap1; Guanylate cyclase activator 1A; guanylate cyclase activator 1a (retina); guanylate cyclase-activating protein, photoreceptor 1; guanylin 1, retina; Guanylyl cyclase-activating protein 1; GUCA; GUCA1; Guca1a; mGCAP1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2978
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P43080
Gene Symbols
Guca1a
Immunogen
KLH conjugated synthetic peptide derived from human GCAP1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Guanylate cyclase-activating protein is a l Ca(2+)-binding protein that upregulates synthesis of cGMP in photoreceptors
- The known mammalian GCAPs are more than 90% similar, consisting of 201 to 205 amino acids, and containing 3 identically conserved Ca(2+)-binding sites
- The GUCA1A gene, also termed GCAP1, is transcribed into a single 1.7-kb mRNA species detectable only in the retina
- In a 4-generation British family with typical clinical features of autosomal dominant cone dystrophy a tyr99-to-cys mutation) in the GUCA1A gene has been identified
- Another family with a pro50-to-leu mutation in GUCA1A demonstrated phenotypic variability ranging from mild photophobia to rod-cone dystrophy
- The mutant protein could activate guanylate cyclase 1 (GUCY2D) and displayed similar calcium sensitivity to wildtype protein
- However, there was a marked increase in the susceptibility to protease degradation and a reduction in the thermal stability of the pro50-to-leu mutation, which may depress cellular concentration and thereby contribute to retinal cell mortality.
Compare Similar Items
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Antigen: GCAP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Guca1a
Gene Alias: BOS_21468; C6orf131; COD3; cone dystrophy 3; CORD14; GC-A; GCAP; GCAP 1; Gcap1; Guanylate cyclase activator 1A; guanylate cyclase activator 1a (retina); guanylate cyclase-activating protein, photoreceptor 1; guanylin 1, retina; Guanylyl cyclase-activating protein 1; GUCA; GUCA1; Guca1a; mGCAP1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2978
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P43080
Gene Symbols: Guca1a
Immunogen: KLH conjugated synthetic peptide derived from human GCAP1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GCAP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Guca1a
Gene Alias:
BOS_21468; C6orf131; COD3; cone dystrophy 3; CORD14; GC-A; GCAP; GCAP 1; Gcap1; Guanylate cyclase activator 1A; guanylate cyclase activator 1a (retina); guanylate cyclase-activating protein, photoreceptor 1; guanylin 1, retina; Guanylyl cyclase-activating protein 1; GUCA; GUCA1; Guca1a; mGCAP1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2978
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P43080
Gene Symbols:
Guca1a
Immunogen:
KLH conjugated synthetic peptide derived from human GCAP1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: GCAP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GUCA1B
Gene Alias: BC018258; BOS_21473; DKFZp686E1183; GCAP 2; GCAP2; GCAP-2; GCAP2 (retina); Guanylate cyclase activator 1B; guanylate cyclase activator 1B (retina); guanylate cyclase activator 1B-like; guanylate cyclase-activating protein, photoreceptor 2; Guanylin 2; Guanylyl cyclase-activating protein 2; GUCA 2; Guca1b; GUCA2; LOC100351008; Retinal guanylyl cyclase activator protein p24; RP48
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2979
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q9UMX6
Gene Symbols: GUCA1B
Immunogen: KLH conjugated synthetic peptide derived from human GCAP2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GCAP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GUCA1B
Gene Alias:
BC018258; BOS_21473; DKFZp686E1183; GCAP 2; GCAP2; GCAP-2; GCAP2 (retina); Guanylate cyclase activator 1B; guanylate cyclase activator 1B (retina); guanylate cyclase activator 1B-like; guanylate cyclase-activating protein, photoreceptor 2; Guanylin 2; Guanylyl cyclase-activating protein 2; GUCA 2; Guca1b; GUCA2; LOC100351008; Retinal guanylyl cyclase activator protein p24; RP48
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2979
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q9UMX6
Gene Symbols:
GUCA1B
Immunogen:
KLH conjugated synthetic peptide derived from human GCAP2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: GCAP3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GUCA1C
Gene Alias: GCAP 3; GCAP3; Guanylate cyclase activator 1C; Guanylyl cyclase-activating protein 3; GUCA1C; Hu-DF1-VAR
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 9626
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: O95843
Gene Symbols: GUCA1C
Immunogen: KLH conjugated synthetic peptide derived from human GCAP3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GCAP3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GUCA1C
Gene Alias:
GCAP 3; GCAP3; Guanylate cyclase activator 1C; Guanylyl cyclase-activating protein 3; GUCA1C; Hu-DF1-VAR
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
9626
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
O95843
Gene Symbols:
GUCA1C
Immunogen:
KLH conjugated synthetic peptide derived from human GCAP3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CKIP-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PLEKHO1
Gene Alias: 2810052M02Rik; BOS_2962; Casein kinase 2-interacting protein 1; C-Jun-binding protein; CK2 interacting protein 1; CK2 interacting protein 1; HQ0024c protein; CK2-interacting protein 1; CKIP1; CKIP-1; HQ0024c; HQ0024c protein; JBP; Jun zipper-associated 2; Jza2; JZA-20; LOC100152184; OC120; Osteoclast maturation-associated gene 120 protein; PH domain-containing family O member 1; pleckstrin homology domain containing O1; pleckstrin homology domain containing, family O member 1; Pleckstrin homology domain-containing family O member 1; pleckstrin homology domain-containing family O member 1-like; PLEKHO1; RGD1311487; RP11-458I7.3; TNF intracellular domain-interacting protein
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 51177
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q53GL0
Gene Symbols: PLEKHO1
Immunogen: KLH conjugated synthetic peptide derived from human CKIP-1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CKIP-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PLEKHO1
Gene Alias:
2810052M02Rik; BOS_2962; Casein kinase 2-interacting protein 1; C-Jun-binding protein; CK2 interacting protein 1; CK2 interacting protein 1; HQ0024c protein; CK2-interacting protein 1; CKIP1; CKIP-1; HQ0024c; HQ0024c protein; JBP; Jun zipper-associated 2; Jza2; JZA-20; LOC100152184; OC120; Osteoclast maturation-associated gene 120 protein; PH domain-containing family O member 1; pleckstrin homology domain containing O1; pleckstrin homology domain containing, family O member 1; Pleckstrin homology domain-containing family O member 1; pleckstrin homology domain-containing family O member 1-like; PLEKHO1; RGD1311487; RP11-458I7.3; TNF intracellular domain-interacting protein
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
51177
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q53GL0
Gene Symbols:
PLEKHO1
Immunogen:
KLH conjugated synthetic peptide derived from human CKIP-1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG