50-198-2849
GLTSCR2/PICT1 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-2849-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-2849 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
GLTSCR2/PICT1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NOP53
Gene Alias
glioma tumor suppressor candidate region gene 2; Glioma tumor suppressor candidate region gene 2 protein; GLT; GLTSCR2; NOP53; p60; PICT1; PICT-1; Protein interacting with carboxyl terminus 1; Ribosome biogenesis protein NOP53
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
29997
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q9NZM5
Gene Symbols
NOP53
Immunogen
KLH conjugated synthetic peptide derived from human GLTSCR2/PICT1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Nucleolar protein which is involved in the integration of the 5S RNP into the ribosomal large subunit during ribosome biogenesis
- In ribosome biogenesis, may also play a role in rRNA transcription
- Also functions as a nucleolar sensor that regulates the activation of p53/TP53 in response to ribosome biogenesis perturbation, DNA damage and other stress conditions
- DNA damage or perturbation of ribosome biogenesis disrupt the interaction between NOP53 and RPL11 allowing RPL11 transport to the nucleoplasm where it can inhibit MDM2 and allow p53/TP53 activation
- It may also positively regulate the function of p53/TP53 in cell cycle arrest and apoptosis through direct interaction, preventing its MDM2-dependent ubiquitin-mediated proteasomal degradation
- Originally identified as a tumor suppressor, it may also play a role in cell proliferation and apoptosis by positively regulating the stability of PTEN, thereby antagonizing the PI3K-AKT/PKB signaling pathway
- May also inhibit cell proliferation and increase apoptosis through its interaction with NF2
- May negatively regulate NPM1 by regulating its nucleoplasmic localization, oligomerization and ubiquitin-mediated proteasomal degradation
- Thereby, may prevent NPM1 interaction with MYC and negatively regulate transcription mediated by the MYC-NPM1 complex
- May also regulate cellular aerobic respiration
- In the cellular response to viral infection, may play a role in the attenuation of interferon-beta through the inhibition of DDX58/RIG-1.
Compare Similar Items
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Antigen: GLTSCR2/PICT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NOP53
Gene Alias: glioma tumor suppressor candidate region gene 2; Glioma tumor suppressor candidate region gene 2 protein; GLT; GLTSCR2; NOP53; p60; PICT1; PICT-1; Protein interacting with carboxyl terminus 1; Ribosome biogenesis protein NOP53
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 29997
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q9NZM5
Gene Symbols: NOP53
Immunogen: KLH conjugated synthetic peptide derived from human GLTSCR2/PICT1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GLTSCR2/PICT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NOP53
Gene Alias:
glioma tumor suppressor candidate region gene 2; Glioma tumor suppressor candidate region gene 2 protein; GLT; GLTSCR2; NOP53; p60; PICT1; PICT-1; Protein interacting with carboxyl terminus 1; Ribosome biogenesis protein NOP53
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
29997
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q9NZM5
Gene Symbols:
NOP53
Immunogen:
KLH conjugated synthetic peptide derived from human GLTSCR2/PICT1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Glucoamylase
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MGAM
Gene Alias: Alpha-glucosidase; brush border hydrolase; Glucan 1,4-alpha-glucosidase; Glucoamylase; Maltase; maltase-glucoamylase; maltase-glucoamylase (alpha-glucosidase); Maltase-glucoamylase, intestinal; MG; MGA; MGAM; MGAML
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 8972
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: O43451
Gene Symbols: MGAM
Immunogen: KLH conjugated synthetic peptide derived from Aspergillus niger Glucoamylase.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Glucoamylase
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MGAM
Gene Alias:
Alpha-glucosidase; brush border hydrolase; Glucan 1,4-alpha-glucosidase; Glucoamylase; Maltase; maltase-glucoamylase; maltase-glucoamylase (alpha-glucosidase); Maltase-glucoamylase, intestinal; MG; MGA; MGAM; MGAML
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
8972
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
O43451
Gene Symbols:
MGAM
Immunogen:
KLH conjugated synthetic peptide derived from Aspergillus niger Glucoamylase.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Glucose 6 phosphatase 2/IGRP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: G6PC2
Gene Alias: G6Pase 2; G-6-Pase 2; G6pc2; G6pc-rs; Glucose-6-phosphatase 2; glucose-6-phosphatase catalytic subunit 2; glucose-6-phosphatase, catalytic, 2; glucose-6-phosphatase, catalytic, related sequence; Igrp; islet-specific G6CP-related protein; Islet-specific glucose-6-phosphatase catalytic subunit-related protein; islet-specific glucose-6-phosphatase-related protein; LOC681817; similar to glucose-6-phosphatase, catalytic, related
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 57818
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q9NQR9
Gene Symbols: G6PC2
Immunogen: KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2/IGRP.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Glucose 6 phosphatase 2/IGRP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
G6PC2
Gene Alias:
G6Pase 2; G-6-Pase 2; G6pc2; G6pc-rs; Glucose-6-phosphatase 2; glucose-6-phosphatase catalytic subunit 2; glucose-6-phosphatase, catalytic, 2; glucose-6-phosphatase, catalytic, related sequence; Igrp; islet-specific G6CP-related protein; Islet-specific glucose-6-phosphatase catalytic subunit-related protein; islet-specific glucose-6-phosphatase-related protein; LOC681817; similar to glucose-6-phosphatase, catalytic, related
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
57818
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q9NQR9
Gene Symbols:
G6PC2
Immunogen:
KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2/IGRP.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Glucose Oxidase
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Gene Alias: GOx
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: __
Gene Symbols: __
Immunogen: KLH conjugated synthetic peptide derived from Penicillium amagasakiense Glucose Oxidase.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Glucose Oxidase
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
GOx
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
KLH conjugated synthetic peptide derived from Penicillium amagasakiense Glucose Oxidase.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG