50-198-2939
pan Granzyme Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-2939-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-2939 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
pan Granzyme
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GZMB
Gene Alias
AI553453; C11; Cathepsin G-like 1; CCP1; CCP-1/C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; Ctla1; Ctla-1; CTSGL1; Cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; Fragmentin; fragmentin 2; Fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; Granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); Granzyme B(G,H); Granzyme-2; GranzymeB; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; GZMB; HLP; Human lymphocyte protein; Lymphocyte protease; Natural killer cell protease 1; OTTHUMP00000028189; RNKP-1; SECT; T-cell serine protease 1-3E
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3002
Content And Storage
-20°C
Form
Liquid
Applications
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P10144
Gene Symbols
GZMB
Immunogen
KLH conjugated synthetic peptide derived from human GZMB.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells
- Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells
- Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells
- The receptor involved in this process has been identified as mannose 6-phosphate receptor which functions as a death receptor for Granzyme B during cytotoxic T cell-induced apoptosis
- Granzyme B enters target cells to cleave caspase-3 and initiate the caspase cascade leading to DNA fragmentation and apoptosis
- Granzyme B can also act through a mitochondrial apoptosis pathway by cleaving the Bid protein
- Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells
- A number of granzymes (A to G) have been isolated and cloned from mouse CTLs and NK cells, however in man, fewer have been cloned and identified.
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Antigen: pan Granzyme
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GZMB
Gene Alias: AI553453; C11; Cathepsin G-like 1; CCP1; CCP-1/C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; Ctla1; Ctla-1; CTSGL1; Cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; Fragmentin; fragmentin 2; Fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; Granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); Granzyme B(G,H); Granzyme-2; GranzymeB; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; GZMB; HLP; Human lymphocyte protein; Lymphocyte protease; Natural killer cell protease 1; OTTHUMP00000028189; RNKP-1; SECT; T-cell serine protease 1-3E
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3002
Content And Storage: -20°C
Form: Liquid
Applications: ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P10144
Gene Symbols: GZMB
Immunogen: KLH conjugated synthetic peptide derived from human GZMB.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
pan Granzyme
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GZMB
Gene Alias:
AI553453; C11; Cathepsin G-like 1; CCP1; CCP-1/C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; Ctla1; Ctla-1; CTSGL1; Cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; Fragmentin; fragmentin 2; Fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; Granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); Granzyme B(G,H); Granzyme-2; GranzymeB; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; GZMB; HLP; Human lymphocyte protein; Lymphocyte protease; Natural killer cell protease 1; OTTHUMP00000028189; RNKP-1; SECT; T-cell serine protease 1-3E
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3002
Content And Storage:
-20°C
Form:
Liquid
Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P10144
Gene Symbols:
GZMB
Immunogen:
KLH conjugated synthetic peptide derived from human GZMB.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: GPR146
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GPR146
Gene Alias: BC003323; G protein-coupled receptor 146; Gpr146; G-protein coupled receptor PGR8; PGR8; Probable G-protein coupled receptor 146
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 115330
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q96CH1
Gene Symbols: GPR146
Immunogen: KLH conjugated synthetic peptide derived from mouse G protein coupled receptor 146.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GPR146
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GPR146
Gene Alias:
BC003323; G protein-coupled receptor 146; Gpr146; G-protein coupled receptor PGR8; PGR8; Probable G-protein coupled receptor 146
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
115330
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q96CH1
Gene Symbols:
GPR146
Immunogen:
KLH conjugated synthetic peptide derived from mouse G protein coupled receptor 146.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: GPR17
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GPR17
Gene Alias: AI853548; DKFZp686M18273; G protein-coupled receptor 17; Gpr17; gpr17 {ECO:0000312; G-protein coupled receptor 17; P2Y-like receptor; R12; RGD:1589785}; UDP/CysLT receptor; Uracil nucleotide/cysteinyl leukotriene receptor; Y12546; Z94155
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2840
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q13304
Gene Symbols: GPR17
Immunogen: KLH conjugated synthetic peptide derived from human G protein coupled receptor 17.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GPR17
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GPR17
Gene Alias:
AI853548; DKFZp686M18273; G protein-coupled receptor 17; Gpr17; gpr17 {ECO:0000312; G-protein coupled receptor 17; P2Y-like receptor; R12; RGD:1589785}; UDP/CysLT receptor; Uracil nucleotide/cysteinyl leukotriene receptor; Y12546; Z94155
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2840
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q13304
Gene Symbols:
GPR17
Immunogen:
KLH conjugated synthetic peptide derived from human G protein coupled receptor 17.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: GPR19
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GPR19
Gene Alias: G protein-coupled receptor 19; GPR19; GPR-NGA; Probable G-protein coupled receptor 19
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2842
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q15760
Gene Symbols: GPR19
Immunogen: KLH conjugated synthetic peptide derived from human G protein coupled receptor 19.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GPR19
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GPR19
Gene Alias:
G protein-coupled receptor 19; GPR19; GPR-NGA; Probable G-protein coupled receptor 19
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2842
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q15760
Gene Symbols:
GPR19
Immunogen:
KLH conjugated synthetic peptide derived from human G protein coupled receptor 19.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG