50-198-3029

CLEC9A Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-3029-Each-of-1 In Stock ₹ 36,897.75

50-198-3029 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

CLEC9A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CLEC9A

Gene Alias

9830005G06Rik; CD370; CLEC9A; C-type lectin domain family 9 member A; C-type lectin domain family 9, member A; Dendritic cell natural killer lectin group receptor 1; DNGR1; Dngr-1; HEEE9341; UNQ9341; UNQ9341/PRO34046

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

283420

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q6UXN8

Gene Symbols

CLEC9A

Immunogen

KLH conjugated synthetic peptide derived from human CLEC9A.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • CLEC9A is a group V CTLR (C-type lectin-like receptor) that functions as an activation receptor and is expressed on myeloid lineage cells
  • This protein is also expressed at the cell surface and acts as glycosylated dimers which mediate endocytosis, but not phagocytosis (Poulin LF et al, 2010)
  • It facilitates antigen uptake and presentation, and may provide a suitable target for antibody-mediated antigen delivery
  • CLEC9A is important for conveying information from necrotic cells to T-cells and defines a pathway by which adaptive immune responses can be initiated in the absence of infection
  • It recruits Syk to mediate sensing of necrosis by the principal DC subset involved in regulating cross priming to cell-associated antigens
  • Signaling via this kinase occurs through a novel pathway involving CARD9 which induce a variety of cellular responses including the induction of cytokines (such as TNF, IL-6, IL-10, IL-23, and IL-2), the respiratory burst, and the production of Arachidonic acid
  • In addition, it also induces TH17 (T-helper type 17) adaptive responses in vivo
  • Expression of CLEC9A is highly restricted in peripheral blood, being detected only on BDCA3+ DCs and on a small subset of CD14+ CD16- monocytes
  • CLEC9A serves as a new marker to distinguish subtypes of DCs.

Compare Similar Items

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Img

Bioss

50-198-3029

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Antigen:
CLEC9A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CLEC9A

Gene Alias:
9830005G06Rik; CD370; CLEC9A; C-type lectin domain family 9 member A; C-type lectin domain family 9, member A; Dendritic cell natural killer lectin group receptor 1; DNGR1; Dngr-1; HEEE9341; UNQ9341; UNQ9341/PRO34046

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
283420

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q6UXN8

Gene Symbols:
CLEC9A

Immunogen:
KLH conjugated synthetic peptide derived from human CLEC9A.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3033

--


Antigen:
CD53

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cd53

Gene Alias:
AI323659; antigen MOX44 identified by monoclonal antibody MRC-OX44; Cd53; CD53 antigen; CD53 glycoprotein; CD53 molecule; CD53 tetraspan antigen; cell surface antigen; Cell surface glycoprotein CD53; EGM_00928; hypothetical protein; Leukocyte antigen MRC OX-44; Leukocyte surface antigen CD53; MOX44; OX44; Ox-44; Tetraspanin-25; transmembrane glycoprotein; TSPAN25; Tspan-25

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
963

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P19397

Gene Symbols:
Cd53

Immunogen:
KLH conjugated synthetic peptide derived from human CD53.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3034

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Antigen:
CED6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GULP1

Gene Alias:
3110030A04Rik; 5730529O06Rik; CED 6; CED6; CED-6; CED-6 protein; Cell death protein 6 homolog; engulfment adapter protein; FLJ31156; GULP; GULP, engulfment adaptor PTB domain containing 1; GULP1; Gulp-2; OTTHUMP00000205908; OTTHUMP00000205909; OTTHUMP00000205911; Protein GULP; PTB domain adapter protein CED-6; PTB domain adaptor protein CED-6; PTB domain-containing engulfment adapter protein 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
51454

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9UBP9

Gene Symbols:
GULP1

Immunogen:
KLH conjugated synthetic peptide derived from human CED6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3035

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Antigen:
CLCNKB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CLCNKB

Gene Alias:
chloride channel K1-like; putative basolateral cTAL chloride channel ClC-Ka; chloride channel K2; Chloride channel Kb; Chloride channel protein ClC-Kb; chloride channel, kidney, B; chloride channel, voltage-sensitive Kb; chloride voltage-gated channel Kb; Clck2; ClC-K2; ClC-K2L; Clc-Ka; Clckb; ClC-Kb; CLCNK; Clcnk1l; CLCNKB; hClC-Kb; LOC100730738; MGC24087; putative basolateral mTAL chloride channel ClC-Ka; RP11-5P18.8

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1188

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P51801

Gene Symbols:
CLCNKB

Immunogen:
KLH conjugated synthetic peptide derived from human CLCNKB.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG