50-198-3098

ATM Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-3098-Each-of-1 In Stock ₹ 36,897.75

50-198-3098 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

ATM

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATM

Gene Alias

AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; ataxia telangiectasia gene mutated in human beings; Ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; ATM; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; Serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

472

Content And Storage

-20°C

Form

Liquid

Applications

Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q13315

Gene Symbols

ATM

Immunogen

KLH conjugated synthetic peptide derived from mouse ATM.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family
  • Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer
  • The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily
  • ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1
  • The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens
  • The ATM’s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases)
  • Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation
  • AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction
  • Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair
  • Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.

Compare Similar Items

Show Difference

Img

Bioss

50-198-3098

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Antigen:
ATM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATM

Gene Alias:
AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; ataxia telangiectasia gene mutated in human beings; Ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; ATM; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; Serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
472

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q13315

Gene Symbols:
ATM

Immunogen:
KLH conjugated synthetic peptide derived from mouse ATM.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3099

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Antigen:
Netrin 5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ntn5

Gene Alias:
BOS_17788; Gm484; LOC100350622; netrin 5; Netrin-1-like protein; Netrin-5; Ntn5; RGD1565197

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
126147

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q8WTR8

Gene Symbols:
Ntn5

Immunogen:
KLH conjugated synthetic peptide derived from human Netrin 5.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3101

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Antigen:
CDH12

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDH12

Gene Alias:
Brain cadherin; brain-cadherin; BR-cadherin; Cadherin; cadherin 12; cadherin 12, type 2 (N-cadherin 2); cadherin, neural type, 2; Cadherin-12; CDH12; CDHB; N-cadherin 2; Neural type cadherin 2; neuronal cadherin 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1010

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P55289

Gene Symbols:
CDH12

Immunogen:
KLH conjugated synthetic peptide derived from human CDH12.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3102

--


Antigen:
Cadherin 20

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDH20

Gene Alias:
BOS_22348; Cad20; Cadherin; cadherin 20; cadherin 20, type 2; cadherin 7; Cadherin-20; Cadherin-7; Cdh20; Cdh7; CDH7L3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
28316

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9HBT6

Gene Symbols:
CDH20

Immunogen:
KLH conjugated synthetic peptide derived from human Cadherin 20.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG