50-198-3133

Claudin 16 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-3133-Each-of-1 In Stock ₹ 36,897.75

50-198-3133 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Claudin 16

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CLDN16

Gene Alias

claudin 16; Claudin-16; CLDN16; H59D2a protein; HOMG3; hypomagnesemia 3, with hypercalciuria and nephrocalcinosis; Paracellin-1; PCLN1; PCLN-1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

10686

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q9Y5I7

Gene Symbols

CLDN16

Immunogen

KLH conjugated synthetic peptide derived from human Claudin 16.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Tight junction group of proteins are a cell-to-cell adhesion structure in epithelial cells that constitute the epithelial junctional complex with adherens junctions and desmosomes
  • Tight junction strands are mainly composed of claudins, occludin, and JAM
  • Claudin-16 belongs to the Claudin family of protein which is composed of 23 integral membrane proteins
  • Claudins are responsible for the formation of tight junction strands and are connected with the actin cytoskeleton mediated by ZO-1
  • Claudin 16, also known as Paracellin-1, is a renal tight junction protein required for paracellular magnesium resorption
  • It is localized in the intercellular junctions of the epithelial cells of the thick ascending limb of Henle′s loop (a TAL marker) are used to localize this specific structure of nephrons in kidney sections
  • Mg2+ resorption occurs in TAL, and Claudin-16 is required for this paracellular function
  • Failure in renal ′handling′ of magnesium can result in hypermagnesemia, whose major direct toxicity implications are cardiovascular as well as renal failure
  • Recent studies have shown that the lack of Claudin-16 proteins contributes to the dysfunction of paracellular renal transport systems.

Compare Similar Items

Show Difference

Img

Bioss

50-198-3133

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Antigen:
Claudin 16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CLDN16

Gene Alias:
claudin 16; Claudin-16; CLDN16; H59D2a protein; HOMG3; hypomagnesemia 3, with hypercalciuria and nephrocalcinosis; Paracellin-1; PCLN1; PCLN-1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10686

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9Y5I7

Gene Symbols:
CLDN16

Immunogen:
KLH conjugated synthetic peptide derived from human Claudin 16.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3135

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Antigen:
Claudin 12

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CLDN12

Gene Alias:
claudin 12; Claudin-12; Cldn12; RGD1561053

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9069

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P56749

Gene Symbols:
CLDN12

Immunogen:
KLH conjugated synthetic peptide derived from human Claudin 12.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3136

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Antigen:
CDC42EP3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDC42EP3

Gene Alias:
3200001F04Rik; AA986861; Binder of Rho GTPases 2; Borg2; CDC42 effector protein (Rho GTPase binding) 3; Cdc42 effector protein 3; CDC42EP3; Cep3; CRIB-containing BORG2 protein; MSE55-related Cdc42-binding protein; MSE55-related protein; UB1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10602

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9UKI2

Gene Symbols:
CDC42EP3

Immunogen:
KLH conjugated synthetic peptide derived from human CDC42EP3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3137

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Antigen:
Ghrelin 28

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GHRL

Gene Alias:
2210006E23Rik; AMCBX1; Appetite-regulating hormone; appetite-regulating hormone; uncharacterized protein LOC58991; exon 2- and 3-deleted preproghrelin; exon 2-deleted preproghrelin; FIP3; FIP-3; Fip3p; Ghr; Ghrelin; ghrelin 27; ghrelin 28; ghrelin and obestatin prepropeptide; ghrelin precursor; ghrelin, growth hormone secretagogue receptor ligand; ghrelin/obestatin; ghrelin/obestatin preprohormone; ghrelin/obestatin prepropeptide; Ghrelin-27; Ghrelin-28; ghrelin-like protein; Ghrl; Growth hormone secretagogue; Growth hormone-releasing peptide; IKK-gamma; In2c-preproghrelin; IP; IP1; IP2; IPD2; m46; Motilin-related peptide; MTLRP; MTLRPAP; NEMO; Obestatin; Obestatin-13; Obestatin-23; OTTHUMP00000207794; OTTHUMP00000207795; OTTHUMP00000207796; OTTHUMP00000207798; prepro-appetite regulatory hormone; preproghrelin; proghrelin; Protein M46; UNQ524/PRO1066

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
51738

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9UBU3

Gene Symbols:
GHRL

Immunogen:
KLH conjugated synthetic peptide of mouse Ghrelin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG