50-198-3275

TLR3 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-3275-Each-of-1 In Stock ₹ 36,897.75

50-198-3275 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

TLR3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TLR3

Gene Alias

AI957183; CD283; IIAE2; Tlr3; TLR-3; toll like receptor 3; Toll-like receptor 3; toll-like receptor 3 variant 1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7098

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O15455

Gene Symbols

TLR3

Immunogen

KLH conjugated synthetic peptide derived from mouse TLR3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • TLR3 (Toll-like receptor 3, CD283) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
  • TLRs are highly conserved from drosophila to humans and share structural and functional similarities
  • TLRs recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
  • The various TLRs exhibit different patterns of expression
  • TLR3 is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes
  • TLR3 recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons
  • Further, TLR3 may play a role in host defense against viruses, and the use of alternative polyadenylation sites to generate different length transcripts has been noted for the TLR3 gene
  • Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans
  • The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition
  • TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway
  • TLR3 is the only human TLR which does not utilize MyD88 as an adaptor molecule instead utilizing TRIF in a signaling path which results in downstream activation of IRF-3 and NF-kB
  • TLR3 activation leads not only to Type I interferon induction but also to other inflammatory cytokines which result in DC maturation
  • TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection
  • Recently it has been shown to recognize viruses such as Influenza A and West Nile Virus and can mediate entry of at least West Nile Virus.

Compare Similar Items

Show Difference

Img

Bioss

50-198-3275

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Antigen:
TLR3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TLR3

Gene Alias:
AI957183; CD283; IIAE2; Tlr3; TLR-3; toll like receptor 3; Toll-like receptor 3; toll-like receptor 3 variant 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7098

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O15455

Gene Symbols:
TLR3

Immunogen:
KLH conjugated synthetic peptide derived from mouse TLR3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3276

--


Antigen:
DUSP26

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DUSP26

Gene Alias:
2310043K02Rik; DSP-4; dual specificity phosphatase 26 (putative); Dual specificity phosphatase SKRP3; Dual specificity protein phosphatase 26; dual-specificity phosphatase SKRP3; DUSP24; DUSP26; LDP4; LDP-4; Low-molecular-mass dual-specificity phosphatase 4; MAP kinase phosphatase 8; MGC1136; MGC2627; Mitogen-activated protein kinase phosphatase 8; MKP8; MKP-8; NATA1; NEAP; neuroendocrine-associated phosphatase; Novel amplified gene in thyroid anaplastic cancer; RGD1310090; Skrp3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
78986

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9BV47

Gene Symbols:
DUSP26

Immunogen:
KLH conjugated synthetic peptide derived from human DUSP26.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3277

--


Antigen:
Promotilin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MLN

Gene Alias:
MAP; MGC138519; MLN; Motilin; Motilin-associated peptide; prepromotilin; Promotilin

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4295

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P12872

Gene Symbols:
MLN

Immunogen:
KLH conjugated synthetic peptide derived from human Promotilin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3278

--


Antigen:
DUX4L9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DUX4L9

Gene Alias:
__

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100288711

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q6RFH8

Gene Symbols:
DUX4L9

Immunogen:
KLH conjugated synthetic peptide derived from human DUX4L9.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG