50-198-3841

IFIT3 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-3841-Each-of-1 In Stock ₹ 36,897.75

50-198-3841 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

IFIT3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IFIT3

Gene Alias

BOS_23283; cig41; CIG49; CIG-49; Garg49; GARG-49; Glucocorticoid-attenuated response gene 49 protein; Ifi49; IFI60; IFI-60K; IFIT3; IFIT-3; IFIT4; IFIT-4; interferon induced protein with tetratricopeptide repeats 3; Interferon-induced 60 kDa protein; Interferon-induced protein with tetratricopeptide repeats 3; interferon-induced protein with tetratricopeptide repeats 3-like; Interferon-induced protein with tetratricopeptide repeats 4; interferon-stimulated protein 60; IRG2; Isg49; ISG60; ISG-60; LOC100341810; P49; P60; Retinoic acid-induced gene G protein; RIG-G; RP11-149I23.4

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3437

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O14879

Gene Symbols

IFIT3

Immunogen

KLH conjugated synthetic peptide derived from human IFIT3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • IFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication
  • Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription
  • Exhibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27
  • Normally, CDKN1B/p27 turnover is regulated by COPS5, which binds CDKN1B/p27 in the nucleus and exports it to the cytoplasm for ubiquitin-dependent degradation
  • IFIT3 sequesters COPS5 in the cytoplasm, thereby increasing nuclear CDKN1B/p27 protein levels
  • Upregulates CDKN1A/p21 by downregulating MYC, a repressor of CDKN1A/p21
  • Can negatively regulate the apoptotic effects of IFIT2.

Compare Similar Items

Show Difference

Img

Bioss

50-198-3841

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Antigen:
IFIT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFIT3

Gene Alias:
BOS_23283; cig41; CIG49; CIG-49; Garg49; GARG-49; Glucocorticoid-attenuated response gene 49 protein; Ifi49; IFI60; IFI-60K; IFIT3; IFIT-3; IFIT4; IFIT-4; interferon induced protein with tetratricopeptide repeats 3; Interferon-induced 60 kDa protein; Interferon-induced protein with tetratricopeptide repeats 3; interferon-induced protein with tetratricopeptide repeats 3-like; Interferon-induced protein with tetratricopeptide repeats 4; interferon-stimulated protein 60; IRG2; Isg49; ISG60; ISG-60; LOC100341810; P49; P60; Retinoic acid-induced gene G protein; RIG-G; RP11-149I23.4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3437

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O14879

Gene Symbols:
IFIT3

Immunogen:
KLH conjugated synthetic peptide derived from human IFIT3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3842

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Antigen:
IFITM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFITM2

Gene Alias:
1-8D; Dispanin subfamily A member 2c; DSPA2c; IFITM2; interferon induced transmembrane protein 2; Interferon-induced transmembrane protein 2; Interferon-inducible protein 1-8D

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10581

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q01629

Gene Symbols:
IFITM2

Immunogen:
KLH conjugated synthetic peptide derived from human IFITM2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3844

--


Antigen:
IFNA14

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFNA14

Gene Alias:
IFNA14; IFN-alpha-14; IFN-alphaH; interferon alpha 14; Interferon alpha-14; Interferon alpha-H; Interferon lambda-2-H; interferon, alpha 14; LeIF H; LEIF2H; OTTMUSG00000007662

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3448

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P01570

Gene Symbols:
IFNA14

Immunogen:
KLH conjugated synthetic peptide derived from human IFNA14.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-3846

--


Antigen:
IFNA5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFNA5

Gene Alias:
Ifa5; IFNA5; IFN-alpha-5; IFN-alphaG; INA5; INFA5; interferon alpha 5; interferon alpha family, gene 5; Interferon alpha-5; Interferon alpha-61; Interferon alpha-G; interferon, alpha 5; LeIF G

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3442

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P01569

Gene Symbols:
IFNA5

Immunogen:
KLH conjugated synthetic peptide derived from human IFNA5.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG