50-198-3983
Phospho-FAK (Tyr577) Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-3983-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-3983 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
Phospho-FAK (Tyr577)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTK2
Gene Alias
BOS_13717; CG10023; CG10023 gene product from transcript CG10023-RG; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFak; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; fak1; Fak56; Fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; Focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; Protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; XELAEV_18032408mg; XPFAK
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5747
Content And Storage
-20°C
Form
Liquid
Applications
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q05397
Gene Symbols
PTK2
Immunogen
KLH conjugated synthetic phosphopeptide derived from human FAK around the phosphorylation site of Tyr577.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Focal Adhesion Kinase (FAK) is a 125 kDa non-receptor protein tyrosine kinase that acts as a substrate for Src and is a key element of integrin signaling
- FAK plays an important role in cell spreading, differentiation, migration, cell death, and acceleration of the G1 to S phase transition of the cell cycle
- Tyrosine 397 is the autophosphorylation site of FAK, and involved in its initial activation
- This phosphorylated site binds Src family SH2 domains and the p85 subunit of PI3-Kinase, and activates cell migration and invasion
- FAK has a central catalytic domain and a C-terminal tail that localizes it to focal adhesions, which are sites where cells attach to the extracellular matrix via surface integrin receptors
- Increased FAK tyrosine phosphorylation occurs upon integrin engagement with fibronectin
- Adhesion of murine NIH3T3 fibroblasts to fibronectin promotes association of the Grb2 adapter protein and c-Src PTK with FAK in vivo, and also results in activation of the ERK2 MAP kinase
- In v-Src-transformed NIH3T3, the association of v-Src, Grb2, and Sos with FAK is independent of cell adhesion to fibronectin
- In vitro the Grb2 SH2 domain binds directly to tyrosine-phosphorylated FAK, and the binding site has been identified as Tyr925 by site directed mutagenesis
- Several transcript variants encoding different isoforms have been found for the FAK gene, but the full-length natures of only three of them have been determined.
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Antigen: Phospho-FAK (Tyr577)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTK2
Gene Alias: BOS_13717; CG10023; CG10023 gene product from transcript CG10023-RG; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFak; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; fak1; Fak56; Fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; Focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; Protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; XELAEV_18032408mg; XPFAK
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5747
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q05397
Gene Symbols: PTK2
Immunogen: KLH conjugated synthetic phosphopeptide derived from human FAK around the phosphorylation site of Tyr577.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-FAK (Tyr577)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTK2
Gene Alias:
BOS_13717; CG10023; CG10023 gene product from transcript CG10023-RG; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFak; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; fak1; Fak56; Fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; Focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; Protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; XELAEV_18032408mg; XPFAK
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5747
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q05397
Gene Symbols:
PTK2
Immunogen:
KLH conjugated synthetic phosphopeptide derived from human FAK around the phosphorylation site of Tyr577.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-JNK1/2/3 (Thr183, Tyr185)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAPK10
Gene Alias: AI849689; AI851083; BOS_24299; BOS_6884; BOS_7042; C230008H04Rik; c-Jun kinase 2; c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 2; c-Jun N-terminal kinase 3; FLJ12099; FLJ33785; hypothetical protein LOC569698; JNK; JNK 46; JNK 55; JNK/SAPK alpha; JNK1; JNK1 beta1 protein kinase; JNK1A2; JNK2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK3; JNK3 alpha protein kinase; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; JNK3A; JNK3B1; JNK3B2; JNK-46; JNK-55; Jun kinase; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAP kinase 9; MAP kinase p49 3F12; MAPK 10; MAPK 8; MAPK 9; Mapk10; MAPK8; MAPK9; MGC50974; Mi; mitogen activated protein kinase 10; mitogen activated protein kinase 8; mitogen activated protein kinase 9; Mitogen-activated protein kinase 10; Mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; Mitogen-activated protein kinase 9; MK10; p493F12; p54 gamma; p54a; p54-alph
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 116554, 25272, 26414, 26419, 26420, 50658, 5599, 5601, 5602
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P45983, P45984, P49185, P49186, P49187, P53779, Q61831, Q91Y86, Q9WTU6
Gene Symbols: MAPK10, MAPK8, MAPK9
Immunogen: KLH conjugated synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Thr183/Tyr185.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-JNK1/2/3 (Thr183, Tyr185)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAPK10
Gene Alias:
AI849689; AI851083; BOS_24299; BOS_6884; BOS_7042; C230008H04Rik; c-Jun kinase 2; c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 2; c-Jun N-terminal kinase 3; FLJ12099; FLJ33785; hypothetical protein LOC569698; JNK; JNK 46; JNK 55; JNK/SAPK alpha; JNK1; JNK1 beta1 protein kinase; JNK1A2; JNK2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK3; JNK3 alpha protein kinase; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; JNK3A; JNK3B1; JNK3B2; JNK-46; JNK-55; Jun kinase; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAP kinase 9; MAP kinase p49 3F12; MAPK 10; MAPK 8; MAPK 9; Mapk10; MAPK8; MAPK9; MGC50974; Mi; mitogen activated protein kinase 10; mitogen activated protein kinase 8; mitogen activated protein kinase 9; Mitogen-activated protein kinase 10; Mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; Mitogen-activated protein kinase 9; MK10; p493F12; p54 gamma; p54a; p54-alph
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
116554, 25272, 26414, 26419, 26420, 50658, 5599, 5601, 5602
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P45983, P45984, P49185, P49186, P49187, P53779, Q61831, Q91Y86, Q9WTU6
Gene Symbols:
MAPK10, MAPK8, MAPK9
Immunogen:
KLH conjugated synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Thr183/Tyr185.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-GAP43 (Ser41)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GAP43
Gene Alias: Axonal membrane protein GAP-43; B-50; Basp2; brain abundant, membrane attached signal protein 2; Calmodulin-binding protein P-57; GAP43; GAP-43; growth accentuating protein 43; growth associated protein 43; Growth-associated protein 43; LOC100345603; MGC156666; nerve growth-related peptide GAP43; Neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; pp46; Protein F1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2596
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P17677
Gene Symbols: GAP43
Immunogen: KLH conjugated synthetic phosphopeptide derived from human GAP43 around the phosphorylation site of Ser41.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-GAP43 (Ser41)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GAP43
Gene Alias:
Axonal membrane protein GAP-43; B-50; Basp2; brain abundant, membrane attached signal protein 2; Calmodulin-binding protein P-57; GAP43; GAP-43; growth accentuating protein 43; growth associated protein 43; Growth-associated protein 43; LOC100345603; MGC156666; nerve growth-related peptide GAP43; Neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; pp46; Protein F1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2596
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P17677
Gene Symbols:
GAP43
Immunogen:
KLH conjugated synthetic phosphopeptide derived from human GAP43 around the phosphorylation site of Ser41.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ZNFN1A2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IKZF2
Gene Alias: A730095J18Rik; ANF1A2; BOS_2069; Helios; IKAROS family zinc finger 2; IKAROS family zinc finger 2 (Helios); Ikaros family zinc finger protein 2; IKZF2; Zfpn1a2; zinc finger DNA binding protein Helios; Zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; Znfn1a2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 22807
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q9UKS7
Gene Symbols: IKZF2
Immunogen: KLH conjugated synthetic peptide derived from human ZNFN1A2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ZNFN1A2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IKZF2
Gene Alias:
A730095J18Rik; ANF1A2; BOS_2069; Helios; IKAROS family zinc finger 2; IKAROS family zinc finger 2 (Helios); Ikaros family zinc finger protein 2; IKZF2; Zfpn1a2; zinc finger DNA binding protein Helios; Zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; Znfn1a2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
22807
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q9UKS7
Gene Symbols:
IKZF2
Immunogen:
KLH conjugated synthetic peptide derived from human ZNFN1A2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG