50-198-4155

IL-12 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-4155-Each-of-1 In Stock ₹ 36,897.75

50-198-4155 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

IL-12

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Il12b

Gene Alias

20C2; BOS_1122; BOS_8400; CLMF; CLMF p35; CLMF p40; CLMF2; cytokine; cytotoxic lymphocyte maturation factor 1, p35; Cytotoxic lymphocyte maturation factor 35 kDa subunit; Cytotoxic lymphocyte maturation factor 40 kDa subunit; IL 12p70; Il12; IL-12; Il-12 p35; IL-12 p75; IL-12 subunit p35; IL-12 subunit p40; IL-12, subunit p35; IL12, subunit p40; Il-12; cytokine; IL12A; IL-12A; IL12A/B; IL12AB; IL12B; IL-12B; IL12P35; IL-12p35; Il12p40; Il-12p40; IL35 subunit; ILN; IMD28; IMD29; Interleukin; interleukin 12 35kDa subunit; interleukin 12 40kDa subunit; interleukin 12 p35 subunit; interleukin 12 p40 subunit precursor; interleukin 12 polypeptide 35; interleukin 12, p35; interleukin 12, p40; interleukin 12a; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); interleukin 12B; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); interleukin 12p35 subunit precursor; interleukin-12 alpha chain; interleukin-12 alpha p40 subunit; interleukin-12 beta chain; interleukin-12 beta p35 subunit; interleukin-12 p35 subunit precursor; interleukin-12 p40; interleukin-12 p40 subunit; interleukin-12 p40 subunit precursor; Interleukin-12 p70; Interleukin-12 subunit alpha; Interleukin-12 subunit beta; Ll12a; MGC151228; MGC151232; natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35; natural killer cell stimulatory factor, 40 kD subunit; NF cell stimulatory factor chain 1; NFSK; NK cell stimulatory factor chain 1; NK cell stimulatory factor chain 2; NKSF; NKSF1; NKSF2; p35; p40

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3592, 3593

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P29459, P29460

Gene Symbols

IL12A, Il12b

Immunogen

KLH conjugated synthetic peptide derived from human IL-12.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Interleukin-12 (IL-12) is a heterodimeric 70 kDa cytokine composed of two covalently linked, glycosylated chains with molecular weights of 40kD (p40) and 35-kD (p35)
  • IL-12 is mainly produced by monocytes, macrophages, and dendritic cells in response to bacterial products such as lipopolysaccharides (LPS), to intracellular pathogens or upon interaction with activated T cells
  • IL-12 was originally discovered because of its ability to induce interferon-gamma (IFN-g) production, cell proliferation, and cytotoxicity mediated by natural killer cells and T cells
  • Studies have established that IL-12 also plays a key role in the development of Th1 responses, leading to IFN-g and IL-2 production
  • These cytokines can in turn promote T-cell responses and macrophage activation
  • Recombinant mouse IL-12 p70 is produced in baculovirus-infected insect cells as an authentic heterodimer of precursor p35 and p40 subunits using a dual promoter expression system
  • IL-12 p70 is distinct from other available forms of the protein in that it is expressed as a true heterodimer, as opposed to a single-chain, pseudo-heterodimer in which the subunits are joined by an artificial linker
  • The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4
  • Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity
  • Human and mouse IL-12 p40 share about 70% amino acid sequence homology.

Compare Similar Items

Show Difference

Img

Bioss

50-198-4155

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Antigen:
IL-12

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il12b

Gene Alias:
20C2; BOS_1122; BOS_8400; CLMF; CLMF p35; CLMF p40; CLMF2; cytokine; cytotoxic lymphocyte maturation factor 1, p35; Cytotoxic lymphocyte maturation factor 35 kDa subunit; Cytotoxic lymphocyte maturation factor 40 kDa subunit; IL 12p70; Il12; IL-12; Il-12 p35; IL-12 p75; IL-12 subunit p35; IL-12 subunit p40; IL-12, subunit p35; IL12, subunit p40; Il-12; cytokine; IL12A; IL-12A; IL12A/B; IL12AB; IL12B; IL-12B; IL12P35; IL-12p35; Il12p40; Il-12p40; IL35 subunit; ILN; IMD28; IMD29; Interleukin; interleukin 12 35kDa subunit; interleukin 12 40kDa subunit; interleukin 12 p35 subunit; interleukin 12 p40 subunit precursor; interleukin 12 polypeptide 35; interleukin 12, p35; interleukin 12, p40; interleukin 12a; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); interleukin 12B; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); interleukin 12p35 subunit precursor; interleukin-12 alpha chain; interleukin-12 alpha p40 subunit; interleukin-12 beta chain; interleukin-12 beta p35 subunit; interleukin-12 p35 subunit precursor; interleukin-12 p40; interleukin-12 p40 subunit; interleukin-12 p40 subunit precursor; Interleukin-12 p70; Interleukin-12 subunit alpha; Interleukin-12 subunit beta; Ll12a; MGC151228; MGC151232; natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35; natural killer cell stimulatory factor, 40 kD subunit; NF cell stimulatory factor chain 1; NFSK; NK cell stimulatory factor chain 1; NK cell stimulatory factor chain 2; NKSF; NKSF1; NKSF2; p35; p40

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3592, 3593

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P29459, P29460

Gene Symbols:
IL12A, Il12b

Immunogen:
KLH conjugated synthetic peptide derived from human IL-12.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4156

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Antigen:
CRMP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DPYSL2

Gene Alias:
AI851130; BOS_9088; Collapsin response mediator protein 2; collapsin response mediator protein hCRMP-2; CRMP2; CRMP-2; DHPRP2; dihydropyrimidinase like 2; dihydropyrimidinase-like 2; Dihydropyrimidinase-related protein 2; DPYL2; Dpysl2; DRP2; DRP-2; Musunc33; N2A3; Neural-specific protein NSP60; TOAD-64; turned on after division 64; Turned on after division 64 kDa protein; turned on after division, 64 kDa protein; ULIP2; ULIP-2; Unc-33-like phosphoprotein 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1808

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q16555

Gene Symbols:
DPYSL2

Immunogen:
KLH conjugated synthetic peptide derived from human CRMP2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4157

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Antigen:
OR52R1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OR52R1

Gene Alias:
Olfactory receptor 52R1; olfactory receptor family 52 subfamily R member 1 (gene/pseudogene); Olfactory receptor OR11-22; olfactory receptor, family 52, subfamily R, member 1; OR11-22; OR52R1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
119695

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q8NGF1

Gene Symbols:
OR52R1

Immunogen:
KLH conjugated synthetic peptide derived from human OR52R1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4159

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Antigen:
OR5H6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OR5H6

Gene Alias:
Olfactory receptor 5H6; olfactory receptor family 5 subfamily H member 6 (gene/pseudogene); Olfactory receptor OR3-11; olfactory receptor, family 5, subfamily H, member 6; OR3-11; OR5H6

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
79295

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q8NGV6

Gene Symbols:
OR5H6

Immunogen:
KLH conjugated synthetic peptide derived from human OR5H6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG