50-198-4491

iNOS Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-4491-Each-of-1 In Stock ₹ 36,897.75

50-198-4491 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

iNOS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Nos2

Gene Alias

Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; Inducible NO synthase; Inducible NOS; iNOS; i-NOS; Inosl; MAC-NOS; Macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); Nitric oxide synthase, inducible; nitric oxide synthase, macrophage; NOS; NOS type II; NOS, type II; NOS2; Nos-2; NOS2A; NOS-II; OTTMUSP00000000202; Peptidyl-cysteine S-nitrosylase NOS2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4843

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P35228

Gene Symbols

Nos2

Immunogen

KLH conjugated synthetic peptide derived from mouse NOS-2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Bethyl Laboratories, Inc

50-264-1013

--

Img

Bioss

50-198-4826

--

Img

Bioss

50-198-4966

--

Img

Bioss

50-198-5036

--

Img

Bioss

50-198-7688

--

Img

Bioss

50-198-4759

--

Img

Bioss

50-198-1976

--

Img

Bioss

50-198-8460

--

Description

  • iNOS (Inducible Nitric oxide, NO, NOS) is an inorganic, gaseous free radical that carries a variety of messages between cells
  • Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO
  • NO production is mediated by members of the nitric oxide synthase (NOS) family
  • iNOS is expressed in liver and inducible by a combination of lipopolysaccharide and certain cytokines
  • NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO
  • Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) and endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned
  • All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains
  • iNOS is found in a variety of cell types including macrophages, hepatocytes, synoviocytes, and smooth muscle cells
  • Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels
  • Protein kinase C-stimulating agents exhibit the same effect on iNOS activity
  • After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time
  • Three related iNOS pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17
  • Diseases associated with iNOS dysfunction include achalasia and impotence.

Compare Similar Items

Show Difference

Img

Bioss

50-198-4491

--


Antigen:
iNOS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nos2

Gene Alias:
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; Inducible NO synthase; Inducible NOS; iNOS; i-NOS; Inosl; MAC-NOS; Macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); Nitric oxide synthase, inducible; nitric oxide synthase, macrophage; NOS; NOS type II; NOS, type II; NOS2; Nos-2; NOS2A; NOS-II; OTTMUSP00000000202; Peptidyl-cysteine S-nitrosylase NOS2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4843

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P35228

Gene Symbols:
Nos2

Immunogen:
KLH conjugated synthetic peptide derived from mouse NOS-2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4493

--


Antigen:
Nurr1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NR4A2

Gene Alias:
HZF3; Hzf-3; Immediate-early response protein NOT; intermediate-early receptor protein; NGFI-B; NGFI-B beta; NGFI-B/nur77 beta-type transcription factor homolog; NOT; Nr4a2; Nuclear orphan receptor HZF-3; nuclear receptor related 1; Nuclear receptor subfamily 4 group A member 2; nuclear receptor subfamily 4 group A member 2 variant TINUR; nuclear receptor subfamily 4 group A member 2 variant NURR1a; nuclear receptor subfamily 4 group A member 2 variant NURR1b; nuclear receptor subfamily 4 group A member 2 variant NURR1c; nuclear receptor subfamily 4 group A member 2 variant NURR2c; nuclear receptor subfamily 4, group A, member 2; nur related protein 1; nur related protein-1, human homolog of; Nurr1; NUR-related factor 1; orphan nuclear receptor NR4A2; Orphan nuclear receptor NURR1; Regenerating liver nuclear receptor 1; Rnr1; RNR-1; SL-322; T-cell nuclear receptor NOT; TINOR; TINUR; transcriptionally inducible nuclear receptor related 1; Transcriptionally-inducible nuclear receptor

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4929

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P43354

Gene Symbols:
NR4A2

Immunogen:
KLH conjugated synthetic peptide derived from human Nurr1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4494

--


Antigen:
CNGA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CNGA2

Gene Alias:
CNCA; CNCA1; CNCG2; Cncg4; CNG channel 2; CNG channel alpha-2; CNG2; CNG-2; Cnga2; cyclic nucleotide gated channel 4; cyclic nucleotide gated channel alpha 2; Cyclic nucleotide-gated cation channel 2; Cyclic nucleotide-gated channel alpha-2; Cyclic nucleotide-gated olfactory channel; Cyclic nucleotide-gated olfactory channel subunit OCNC1; cyclic-nucleotide-gated cation channel 2; OCNC1; OCNCa; OCNCALPHA; OLFCH

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1260

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q16280

Gene Symbols:
CNGA2

Immunogen:
KLH conjugated synthetic peptide derived from human CNGA2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4497

--


Antigen:
PARP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Parp1

Gene Alias:
5830444G22Rik; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase 1; ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); Adprp; ADPRT; ADPRT 1; ADPRT1; AI893648; ARTD1; BOS_15645; C80510; DNA ADP-ribosyltransferase PARP1; I79_014850; msPARP; NAD(+) ADP-ribosyltransferase 1; NAD(+) pADPRT-1; pADPRT-1; Parp; PARP1; PARP-1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; poly (ADP-ribose) polymerase); Poly [ADP-ribose] polymerase 1; poly ADP-ribose polymerase; poly(ADP-ribose) polymerase; poly(ADP-ribose) polymerase 1; poly(ADP-ribose) polymerase PARP-1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; Poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL; Protein poly-ADP-ribosyltransferase PARP1; sPARP-1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
142

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P09874

Gene Symbols:
Parp1

Immunogen:
KLH conjugated synthetic peptide derived from human PARP1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG