50-198-4670

Phospho-Tau (Thr548) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-4670-Each-of-1 In Stock ₹ 36,897.75

50-198-4670 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-Tau (Thr548)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAPT

Gene Alias

AI413597; AW045860; BOS_19251; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; Mapt; MAPTL; MGC138549; microtubule associated protein tau; Microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Neuronal Marker; Paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; Tau-4; Tau5

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4137

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P10636

Gene Symbols

MAPT

Immunogen

KLH conjugated synthetic phosphopeptide derived from human Tau around the phosphorylation site of Thr548 [VR (p-T)PP].

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Tau is a neuronal microtubule-associated protein found predominantly on axons
  • The function of Tau is to promote tubulin polymerization and stabilize microtubules
  • The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
  • Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
  • The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
  • In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer′s diseases (AD) brain
  • Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, ultimately leading to the degeneration of the affected neurons
  • Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
  • Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick′s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Compare Similar Items

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Img

Bioss

50-198-4670

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Antigen:
Phospho-Tau (Thr548)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597; AW045860; BOS_19251; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; Mapt; MAPTL; MGC138549; microtubule associated protein tau; Microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Neuronal Marker; Paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; Tau-4; Tau5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4137

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P10636

Gene Symbols:
MAPT

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Tau around the phosphorylation site of Thr548 [VR (p-T)PP].

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4671

--


Antigen:
ERG/KCNH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCNH2

Gene Alias:
AI326795; BOS_4785; CERG; c-ERG; DERG; Eag homolog; eag related protein 1; eag-related protein 1; Erg; ERG1; ERG-1; ether-a-go-go related gene potassium channel 1; Ether-a-go-go-related gene potassium channel 1; ether-a-go-go-related potassium channel protein; ether-a-go-go-related protein 1; gp-erg; HERG; H-ERG; HERG1; HERG-1; KCNH2; Kv11.1; LQT; Lqt2; M-erg; Merg1; M-erg1; merg1a; merg1b; potassium channel protein ERG; potassium channel, voltage gated eag related subfamily H, member 2; Potassium voltage-gated channel subfamily H member 2; potassium voltage-gated channel, subfamily H (eag-related), member 2; ra-erg; RERG; r-ERG; SQT1; ventricular ERG K+ channel subunit; voltage-gated potassium channel 11.1; Voltage-gated potassium channel subunit Kv11.1; voltage-gated potassium channel, subfamily H, member 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3757

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q12809

Gene Symbols:
KCNH2

Immunogen:
KLH conjugated synthetic peptide derived from human ERG/KCNH2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4672

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Antigen:
FABP5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fabp5

Gene Alias:
C-FABP; Cutaneous fatty acid-binding protein; DA11; EFABP; E-FABP; E-FABPPAFABP; Epidermal-type fatty acid-binding protein; epithelial fatty acid-binding protein; Fabp5; Fabpe; fatty acid binding protein 5; fatty acid binding protein 5 (psoriasis-associated); fatty acid binding protein 5, epidermal; Fatty acid-binding protein 5; Fatty acid-binding protein, epidermal; fatty acid-binding protein, epidermal; uncharacterized protein LOC16592; Keratinocyte lipid-binding protein; KFABP; Klbp; Mal1; PAFABP; PA-FABP; PA-FABPepidermal; Psoriasis-associated fatty acid-binding protein homolog

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2171

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q01469

Gene Symbols:
Fabp5

Immunogen:
KLH conjugated synthetic peptide derived from human Fatty Acid Binding Protein 5.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4673

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Antigen:
PKA C alpha+beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKACA

Gene Alias:
cAMP-dependent protein kinase C beta; cAMP-dependent protein kinase catalytic beta subunit isoform 4ab; cAMP-dependent protein kinase catalytic subunit alpha; cAMP-dependent protein kinase catalytic subunit alpha, isoform 1; cAMP-dependent protein kinase catalytic subunit beta; cAMP-dependent protein kinase catalytic subunit C alpha; Cs-PKA; PKA C-alpha; PKA C-beta; PKACA; Pkacb; PKCA1; PKCD; PPNAD4; PRKACA; PRKACB; protein kinase A; protein kinase A catalytic subunit; protein kinase A catalytic subunit beta; protein kinase cAMP-activated catalytic subunit alpha; protein kinase cAMP-activated catalytic subunit beta; protein kinase, cAMP dependent, catalytic, alpha; protein kinase, cAMP dependent, catalytic, beta; protein kinase, cAMP-dependent, alpha catalytic subunit; protein kinase, cAMP-dependent, beta catalytic subunit; protein kinase, cAMP-dependent, catalytic, alpha; protein kinase, cAMP-dependent, catalytic, beta; sperm cAMP-dependent protein kinase catalytic subunit

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18747, 18749, 25636, 293508, 5566, 5567

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P05132, P17612, P22694, P27791, P68181, P68182

Gene Symbols:
PRKACA, PRKACB

Immunogen:
KLH conjugated synthetic peptide derived from human PKA beta.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG