50-198-4767

CD27/TNFRSF7 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-4767-Each-of-1 In Stock ₹ 36,897.75

50-198-4767 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

CD27/TNFRSF7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CD27

Gene Alias

CD antigen 27; Cd27; CD27 antigen; CD27 molecule; CD27L receptor; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; Tnfrsf7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7; uncharacterized protein LOC100520023

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

939

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P26842

Gene Symbols

CD27

Immunogen

KLH conjugated synthetic peptide derived from human CD27 .

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • CD27 is a 50 kDa member of the tumor necrosis factor (TNF) receptor superfamily that includes CD40 and CD30
  • The TNF superfamily members are known for the regulation of cell proliferation and death
  • In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined to lymphocytes
  • High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors
  • CD70 expression requires additional co-stimulatory and/or pro-inflammatory signals
  • CD27 is expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells
  • Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid
  • Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies
  • RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70
  • CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor
  • Diseases associated with CD27 dysfunction include Lymphoproliferative Syndrome 2 and Autosomal Recessive Lymphoproliferative Syndrome.

Compare Similar Items

Show Difference

Img

Bioss

50-198-4767

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Antigen:
CD27/TNFRSF7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD27

Gene Alias:
CD antigen 27; Cd27; CD27 antigen; CD27 molecule; CD27L receptor; S152; S152. LPFS2; sCD27; soluble CD27; T cell activation antigen S152; T14; T-cell activation antigen CD27; Tnfrsf7; Tp55; Tumor necrosis factor receptor superfamily member 7; tumor necrosis factor receptor superfamily, member 7; uncharacterized protein LOC100520023

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
939

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P26842

Gene Symbols:
CD27

Immunogen:
KLH conjugated synthetic peptide derived from human CD27 .

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4768

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Antigen:
TNFRSF12A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFRSF12A

Gene Alias:
AI255180; BOS_22618; C87282; CD266; FGF-inducible 14; Fgfrp2; fibroblast growth factor regulated protein 2; Fibroblast growth factor-inducible immediate-early response protein 14; Fibroblast growth factor-regulated protein 2; FN14; HPIP; TNF receptor superfamily member 12A; Tnfrsf12a; Tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily, member 12A; TweakR; TWEAK-R; Tweak-receptor; type I transmembrane protein Fn14

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
51330

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9NP84

Gene Symbols:
TNFRSF12A

Immunogen:
KLH conjugated synthetic peptide derived from human TNFRSF12A.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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50-198-477

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Antigen:
__

Classification:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
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Img

Bioss

50-198-4770

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Antigen:
CD30

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFRSF8

Gene Alias:
Ber-H2; CD30; CD30 antigen; CD30 molecule; CD30L receptor; cytokine receptor CD30; D1S166E; Ki; Ki-1; Ki-1 antigen; Lymphocyte activation antigen CD30; sCD30; soluble CD30; TNF receptor superfamily member 8; Tnfrsf8; Tumor necrosis factor receptor superfamily member 8; tumor necrosis factor receptor superfamily, member 8; Tumor necrosis factor superfamily member 8; tumor necrosis factor superfamily, member CD30

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
943

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P28908

Gene Symbols:
TNFRSF8

Immunogen:
KLH conjugated synthetic peptide derived from human CD30.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG