50-198-4783

Phospho-NFKBIA (Ser32, Ser36) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-4783-Each-of-1 In Stock ₹ 36,897.75

50-198-4783 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-NFKBIA (Ser32, Ser36)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NFKBIA

Gene Alias

AI462015; BOS_20329; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; ikappaBalpha; I-kappaBalpha; I-kappa-B-alpha; IKBA; IKBalpha; IkB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; NFKBIA; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4792

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P25963

Gene Symbols

NFKBIA

Immunogen

KLH conjugated synthetic phosphopeptide derived from human IKB alpha around the phosphorylation site of Ser32/36.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity
  • The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol
  • The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus
  • A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha
  • These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses
  • In humans, the gene is located on the q arm of chromosome 14
  • Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB
  • IkB kinase alpha (IKK alpha), previously designated CHUK, interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation Serines 32 and 36
  • IKK alpha appears to be critical for NFkB activation in response to proinflammatory cytokines
  • Phosphorylation of IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1
  • The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma, and each appear to make essential contributions to IkB phosphorylation.

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Bioss

50-198-4783

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Antigen:
Phospho-NFKBIA (Ser32, Ser36)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NFKBIA

Gene Alias:
AI462015; BOS_20329; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; ikappaBalpha; I-kappaBalpha; I-kappa-B-alpha; IKBA; IKBalpha; IkB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; NFKBIA; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4792

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P25963

Gene Symbols:
NFKBIA

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human IKB alpha around the phosphorylation site of Ser32/36.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4784

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Antigen:
CCR5/CD195

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCR5

Gene Alias:
AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; CHEMR13; CKR5; CKR-5; CMKBR5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1234

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P51681

Gene Symbols:
CCR5

Immunogen:
KLH conjugated synthetic peptide derived from human CCR-5.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4786

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Antigen:
GTSE-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GTSE1

Gene Alias:
B99; G2 and S phase-expressed protein 1; G-2 and S-phase expressed 1; G2 and S-phase expressed 1; GTSE1; GTSE-1; Protein B99 homolog

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
51512

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9NYZ3

Gene Symbols:
GTSE1

Immunogen:
KLH conjugated synthetic peptide derived from human GTSE-1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4787

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Antigen:
CD72/Ly-32

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD72

Gene Alias:
B-cell differentiation antigen CD72; Cd72; CD72 antigen; Cd72 molecule; CD72b; CD72c; Ly-19; Ly32; Ly-32; LYB2; Lyb-2; Ly-m19; Lymphocyte antigen 32; RP11-331F9.9

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
971

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P21854

Gene Symbols:
CD72

Immunogen:
KLH conjugated synthetic peptide derived from human CD72.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG