50-198-4859

IL-31RA/CRL3 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-4859-Each-of-1 In Stock ₹ 36,897.75

50-198-4859 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

IL-31RA/CRL3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IL31RA

Gene Alias

class I cytokine receptor; CRL; CRL 3; CRL3; CRL3Glmr; cytokine receptor NR10; Cytokine receptor-like 3; GLM R; Glmr; GLM-R; GLM-RMGC125346; GP130 like receptor; Gp130-like monocyte receptor; Gp130-like receptor; GPL; HGLM R; HGLMR; hGLM-R; IL 31RA; IL-31 receptor subunit alpha; IL31R subunit alpha; IL-31R subunit alpha; Il31ra; IL-31RA; IL-31RAGPLCRL; IL-31R-alpha; interleukin 31 receptor A; interleukin 31RA; Interleukin-31 receptor subunit alpha; MGC125346; mGLM-R; Novel cytokine receptor 10; NR10; PLCA 2; PLCA2; PRO21384; soluble type I cytokine receptor CRL3; UNQ6368/PRO21073/PRO21384; ZcytoR17

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

133396

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q8NI17

Gene Symbols

IL31RA

Immunogen

KLH conjugated synthetic peptide derived from human IL-31RA .

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Bioss

50-198-4918

--

Img

Bioss

50-198-4839

--

Img

Bioss

50-198-4849

--

Img

Bioss

50-198-4583

--

Img

Bioss

50-198-4841

--

Img

Bioss

50-198-1725

--

Img

Bioss

50-228-1257

--

Img

Bioss

50-228-1635

--

Description

  • IL-31 is a T cell cytokine that is preferentially produced by T helper type 2 cells
  • IL-31 signals through a heterodimeric receptor composed of the IL-31 receptor (IL-31R) and the oncostatin M receptor (OSM)
  • This receptor complex recruits JAK1, JAK2, Stat1, Stat3 and Stat5 signaling pathways, as well as the PI3 kinase/AKT cascade
  • SHP-2 and Shc adapter molecules are also recruited and contribute to an increased activation of the MAP kinase pathway in response to IL-31
  • Overexpression of IL-31 in mice results in pruritus and skin dermatitis resembling human atopic dermatitis (AD)
  • Comparisons between skin from patients with AD and healthy skin showed IL-31R expression at higher levels on epidermal keratinocytes in AD samples
  • Infiltrating cells, more numerous in skin from patients with AD compared with that of healthy individuals, expressed IL-31 mRNA
  • IL-31 may participate in the cause of itch sensation and promote scratching behavior in NC/Nga mice with atopic dermatitis, and may represent a novel target for antipruritic drug development.

Compare Similar Items

Show Difference

Img

Bioss

50-198-4859

--


Antigen:
IL-31RA/CRL3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL31RA

Gene Alias:
class I cytokine receptor; CRL; CRL 3; CRL3; CRL3Glmr; cytokine receptor NR10; Cytokine receptor-like 3; GLM R; Glmr; GLM-R; GLM-RMGC125346; GP130 like receptor; Gp130-like monocyte receptor; Gp130-like receptor; GPL; HGLM R; HGLMR; hGLM-R; IL 31RA; IL-31 receptor subunit alpha; IL31R subunit alpha; IL-31R subunit alpha; Il31ra; IL-31RA; IL-31RAGPLCRL; IL-31R-alpha; interleukin 31 receptor A; interleukin 31RA; Interleukin-31 receptor subunit alpha; MGC125346; mGLM-R; Novel cytokine receptor 10; NR10; PLCA 2; PLCA2; PRO21384; soluble type I cytokine receptor CRL3; UNQ6368/PRO21073/PRO21384; ZcytoR17

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
133396

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q8NI17

Gene Symbols:
IL31RA

Immunogen:
KLH conjugated synthetic peptide derived from human IL-31RA .

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4861

--


Antigen:
IL-33

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL33

Gene Alias:
9230117N10Rik; C9orf26; DVS27; DVS27-related protein; H-IL-33; IL1F11; IL-1F11; IL33; IL-33; ILN; Interleukin; interleukin 33; Interleukin-1 family member 11; Interleukin33; Interleukin-33; Interleukin-33 (109-270); Interleukin-33 (95-270); Interleukin-33 (99-270); Interleukin-33(102-266); Interleukin-33(109-266); NFEHEV; NFHEV; NF-HEV; nuclear factor for high endothelial venules; Nuclear factor from high endothelial venules; RGD1311155; RP11-575C20.2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
90865

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O95760

Gene Symbols:
IL33

Immunogen:
KLH conjugated synthetic peptide derived from mouse IL-33.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4863

--


Antigen:
ERK1 + 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPK1

Gene Alias:
12559; 9030612K14Rik; AA407128; AU018647; BcDNA:RE08694; BOS_16809; BOS_22892; C78273; CG12559; CG12559 gene product from transcript CG12559-RC; CG12559-PA; CG12559-PC; CG12559-PD; CG12559-PE; CG12559-PG; CG12559-PH; CG12559-PI; CG18732; CT34260; CT39192; DERK; D-ERK; DERK-A; Diphospho-ERK; dm-dpERK; Dmel\CG12559; Dmel_CG12559; DmErk; DmERKA; DmERK-A; DmMAPK; DpERK; dp-ERK; dpERK1; dpMAPK; drosophila ERK; Dsor2; E(sina)7; EC2-1; EK2-1; enhancer of seven in absentia 7; ERK; Erk MAP kinase; Erk/Map kinase; ERK/rolled; Erk1; ERK-1; ERK1b; Erk2; ERK-2; ERKa; ERK-A; ERT1; ERT2; Esrk1; extracellular signal-regulated kinase; Extracellular signal-regulated kinase 1; Extracellular signal-regulated kinase 2; extracellular signal-regulated kinase A; extracellular signal-regulated kinase-2; extracellular signal-related kinase 1; Extracellular-regulated kinase A; extracellular-signal-regulated kinase 2; Extracellular-signal-related kinase A; EY2-2; fi06b09; GroupII; HS44KDAP; HUMKER1A; I79_009500;

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
116590, 26413, 26417, 50689, 5594, 5595

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P21708, P27361, P28482, P63085, P63086, Q63844

Gene Symbols:
MAPK1, MAPK3

Immunogen:
KLH conjugated synthetic peptide derived from mouse ERK2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-4864

--


Antigen:
PGE2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ptges2

Gene Alias:
0610038H10Rik; BOS_12067; C79137; C9orf15; FLJ14038; gamma-interferon-activated transcriptional element-binding factor 1; GATE-binding factor 1; Gbf1; GBF-1; membrane-associated prostaglandin E synthase 2; Membrane-associated prostaglandin E synthase-2; MGC11289; Microsomal prostaglandin E synthase 2; microsomal prostaglandin E synthase-2; mPGE synthase-2; Mpges2; mPGES-2; Pges2; Prostaglandin E synthase 2; Prostaglandin E synthase 2 truncated form; Prostaglandin-H(2) E-isomerase; PTGES2; RP11-395P17.2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
80142

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9H7Z7

Gene Symbols:
Ptges2

Immunogen:
KLH conjugated synthetic peptide derived from mouse PGE2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG