50-198-5085

Phospho-PDPK1 (Tyr373, Tyr376) Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-5085-Each-of-1 In Stock ₹ 36,897.75

50-198-5085 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-PDPK1 (Tyr373, Tyr376)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Pdpk1

Gene Alias

3-phosphoinositide dependent protein kinase 1; 3-phosphoinositide dependent protein kinase-1; 3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; HGNC:8809; hPDK1; isoenzyme 1; kinase isoenzyme 1; lipoamide; mPDK1; OTTHUMP00000174525; OTTHUMP00000205076; PDK1; Pdpk1; PDPK2; PDPK2P; PkB kinase; PkB kinase like gene 1; PkB-like 1; PRO0461; Protein kinase B kinase

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

18607, 5170, 81745

Content And Storage

-20°C

Form

Liquid

Applications

ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O15530, O55173, Q9Z2A0

Gene Symbols

Pdpk1

Immunogen

KLH conjugated synthetic phosphopeptide derived from human PDPK1 around the phosphorylation site of (Y373+Y376).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PDPK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases
  • PDPK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop
  • PDPK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate
  • Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase, and the stimulation of glycogen synthesis
  • Because of the role that PDPK1 plays in insulin-induced glycogen synthesis and PKC activation, it is a potentially important target for metabolic drug research.

Compare Similar Items

Show Difference

Img

Bioss

50-198-5085

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Antigen:
Phospho-PDPK1 (Tyr373, Tyr376)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pdpk1

Gene Alias:
3-phosphoinositide dependent protein kinase 1; 3-phosphoinositide dependent protein kinase-1; 3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; HGNC:8809; hPDK1; isoenzyme 1; kinase isoenzyme 1; lipoamide; mPDK1; OTTHUMP00000174525; OTTHUMP00000205076; PDK1; Pdpk1; PDPK2; PDPK2P; PkB kinase; PkB kinase like gene 1; PkB-like 1; PRO0461; Protein kinase B kinase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18607, 5170, 81745

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O15530, O55173, Q9Z2A0

Gene Symbols:
Pdpk1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human PDPK1 around the phosphorylation site of (Y373+Y376).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5086

--


Antigen:
Phospho-e4EBP1 (Ser65)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF4EBP1

Gene Alias:
4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; Eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1978

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q13541

Gene Symbols:
EIF4EBP1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from mouse 4EBP1 around the phosphorylation site of Ser65.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5087

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Antigen:
Phospho-e4EBP1 (Thr37, Thr46)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF4EBP1

Gene Alias:
4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; Eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
116636, 13685, 1978

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q13541, Q60876, Q62622

Gene Symbols:
EIF4EBP1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human 4EBP1 around the phosphorylation site of Thr37/46.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5089

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Antigen:
Phospho-ALK (Tyr1278, Tyr1282, Tyr1283)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALK

Gene Alias:
ALK; ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; EC 2.7.10.1; kinase ALK; mutant anaplastic lymphoma kinase; NBLST3; p80; Tcrz; TFG/ALK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
238

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9UM73

Gene Symbols:
ALK

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human ALK around the phosphorylation site of Tyr1278/1282/1283.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG