50-198-5110

Phospho-Bcl-2 (Ser70) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-5110-Each-of-1 In Stock ₹ 36,897.75

50-198-5110 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-Bcl-2 (Ser70)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Bcl2

Gene Alias

Apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; Bcl2; Bcl-2; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

596

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P10415

Gene Symbols

Bcl2

Immunogen

KLH conjugated synthetic phosphopeptide derived from rat Bcl-2 around the phosphorylation site of Ser70.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Bioss

50-198-2354

--

Img

Abbomax Inc

50-220-3834

--

Img

Bioss

50-198-2356

--

Img

Bioss

50-198-5404

--

Img

Bioss

50-198-5142

--

Img

Bioss

50-198-5079

--

Img

Bioss

50-198-5102

--

Img

Bioss

50-198-2382

--

Description

  • BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
  • The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
  • Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
  • Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
  • Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
  • Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
  • In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
  • Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
  • The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.

Compare Similar Items

Show Difference

Img

Bioss

50-198-5110

--


Antigen:
Phospho-Bcl-2 (Ser70)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
Apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; Bcl2; Bcl-2; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P10415

Gene Symbols:
Bcl2

Immunogen:
KLH conjugated synthetic phosphopeptide derived from rat Bcl-2 around the phosphorylation site of Ser70.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5112

--


Antigen:
Phospho-Btk (Ser180)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BTK

Gene Alias:
agammaglobulinaemia tyrosine kinase; Agammaglobulinemia tyrosine kinase; AGMX1; AI528679; AT; ATK; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton′s tyrosine kinase; BTK; dominant-negative kinase-deficient Brutons tyrosine kinase; IMD1; Kinase EMB; MGC126261; MGC126262; OTTHUMP00000023677; PSCTK1; RP1-164F3.2; truncated Bruton agammaglobulinemia tyrosine kinase; Tyrosine-protein kinase BTK; Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB); tyrosine-protein kinase BTK isoform (lacking exon 13 to 17); tyrosine-protein kinase BTK isoform (lacking exon 14); xid; XLA; X-linked immune deficiency

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
695

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q06187

Gene Symbols:
BTK

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Btk around the phosphorylation site of Ser180 [GS (p-S)HR].

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5115

--


Antigen:
Phospho-CEBP alpha (Ser21)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CEBPA

Gene Alias:
BOS_17487; C/EBP alpha; C/ebpalpha; C/EBP-alpha; CAAT/enhancer-binding protein DNA-binding protein; CAAT/enhancer-binding protein, DNA-binding protein; CBF-A; CCAAT/enhancer binding protein (C/EBP), alpha; CCAAT/enhancer binding protein alpha; CCAAT/enhancer binding protein, alpha; CCAAT/enhancer-binding protein alpha; Cebp; Cebpa; DBPCEP; OTTHUMP00000220269

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1050

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P49715

Gene Symbols:
CEBPA

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human CDBP alpha around the phosphorylation site of Ser21.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5116

--


Antigen:
Phospho-CEBP alpha (Thr226)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CEBPA

Gene Alias:
BOS_17487; C/EBP alpha; C/ebpalpha; C/EBP-alpha; CAAT/enhancer-binding protein DNA-binding protein; CAAT/enhancer-binding protein, DNA-binding protein; CBF-A; CCAAT/enhancer binding protein (C/EBP), alpha; CCAAT/enhancer binding protein alpha; CCAAT/enhancer binding protein, alpha; CCAAT/enhancer-binding protein alpha; Cebp; Cebpa; DBPCEP; OTTHUMP00000220269

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1050

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P49715

Gene Symbols:
CEBPA

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human CEBP alpha around the phosphorylation site of Thr226.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG