50-198-5220

Phospho-FGFR1 (Tyr653, Tyr654) Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-5220-Each-of-1 In Stock ₹ 36,897.75

50-198-5220 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-FGFR1 (Tyr653, Tyr654)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FGFR1

Gene Alias

2.7.10.1; AW208770; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R; bFGF-R-1; BOS_23880; CD331; CD331 antigen; CEK; CEK1; cek1 protein; c-fgr; Eask; ECCL; FGF receptor-1; FGFBR; Fgfr1; FGFR-1; FGFR1/PLAG1 fusion; FGFRI; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome); Flg; FLT2; FLT-2; Fms-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; KAL2; MFR; N-sam; OGD; Proto-oncogene c-Fgr; Tyrosine kinase receptor CEK1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

14182, 2260, 79114

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P11362, P16092, Q04589

Gene Symbols

FGFR1

Immunogen

KLH conjugated synthetic phosphopeptide derived from human FGFR1 around the phosphorylation site of Tyr653/654.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • FGFR1 (fibroblast growth factor receptor 1) is a member of the fibroblast growth factor receptor family containing an Ig-like domain and a tyrosine kinase domain
  • FGFR1 has multiple isoforms and is a Type I membrane protein
  • FGFR family members differ from one another in their ligand affinities and tissue distribution
  • A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain
  • The extracellular portion of FGFR1 interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation
  • FGFR1 binds both acidic and basic fibroblast growth factors and is involved in limb induction
  • FGFR1 can be modified by phosphorylation and can bind basic/acidic fibroblast factor depending on the receptor isoform
  • FGFR1 has been shown to interact with N-cadherin and NCAM
  • Four genes encoding for high affinity cell surface FGF receptors (FGFRs) have been identified: FGFR-1, FGFR-2, FGFR-3 and FGFR-4.FGFRs are members of the tyrosine kinase family of growth factor receptors
  • At the mRNA level, FGFR1 is highly expressed in developing human tissues including the brain, vascular basement membrane and skin
  • Defects in FGFR1 result in Pfeiffer syndrome associated with craniosynostosis
  • Other defects in FGFR1 are responsible for several diseases which include Pfeiffer syndrome (PS), idiopathic hypogonadotropic hypogonadism (IHH), Kallmann syndrome type 2 (KAL2), osteoglophonic dysplasia (OGD), non-syndromic trigonocephaly, Jackson-Weiss syndrome, Antley-Bixler syndrome
  • Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.

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Bioss

50-198-5220

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Antigen:
Phospho-FGFR1 (Tyr653, Tyr654)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FGFR1

Gene Alias:
2.7.10.1; AW208770; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R; bFGF-R-1; BOS_23880; CD331; CD331 antigen; CEK; CEK1; cek1 protein; c-fgr; Eask; ECCL; FGF receptor-1; FGFBR; Fgfr1; FGFR-1; FGFR1/PLAG1 fusion; FGFRI; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome); Flg; FLT2; FLT-2; Fms-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; KAL2; MFR; N-sam; OGD; Proto-oncogene c-Fgr; Tyrosine kinase receptor CEK1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14182, 2260, 79114

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P11362, P16092, Q04589

Gene Symbols:
FGFR1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human FGFR1 around the phosphorylation site of Tyr653/654.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5221

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Antigen:
Phospho-JAK2 (Tyr221)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3717

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O60674

Gene Symbols:
JAK2

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human JNK2 around the phosphorylation site of Tyr221.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5222

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Antigen:
Phospho-c-Jun (Ser63)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JUN

Gene Alias:
Activator protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; c-jun; C-JUN protein; c-jun transcription factor; enhancer-binding protein AP1; I79_009953; immediate early; Jun; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; p39; Proto-oncogene c-Jun; Rjg-9; Transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3725

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P05412

Gene Symbols:
JUN

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human c-Jun around the phosphorylation site of Ser63.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5223

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Antigen:
Phospho-HER2 (Tyr1248)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERBB2

Gene Alias:
avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); CD antigen CD340; CD340; c-erb B2/neu protein; c-erbB2; c-erbB-2; c-neu; epidermal growth factor receptor-related protein; ERBB2; Erbb-2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; erb-b2 receptor tyrosine kinase 2; HER2; HER-2; HER-2/neu; herstatin; human epidermal growth factor receptor 2; Kiaa3023; metas; Metastatic lymph node gene 19 protein; mKIAA3023; MLN 19; MLN19; NEU; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; NGL; p185erbB2; p185neu; phospho ErbB2; Proto-oncogene c-ErbB-2; Proto-oncogene Neu; Receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2064

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P04626

Gene Symbols:
ERBB2

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human HER2 around the phosphorylation site of Tyr1248.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG