50-198-5296

Phospho-Nucleophosmin (Ser4) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-5296-Each-of-1 In Stock ₹ 36,897.75

50-198-5296 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-Nucleophosmin (Ser4)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NPM1

Gene Alias

B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; NPM; Npm1; Nucleolar phosphoprotein B23; nucleolar protein B23.1; Nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; Numatrin; numatrin antibody; testicular tissue protein Li 128

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4869

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P06748

Gene Symbols

NPM1

Immunogen

KLH conjugated synthetic phosphopeptide derived from human Nucleophosmin around the phosphorylation site of Ser4.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • NPM1 (Nucleophosmin 1, B23, nutramin, NO38) is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication, and regulation of p53
  • NPM1 continuously shuttles between the nucleus, cytoplasm, nucleolus and chaperoning core histones from the nucleus to the cytoplasm
  • NPM1 has been shown to bind nucleic acid, prevent protein aggregation via its chaperon activities, protect enzymes during thermal denaturation, and facilitate renaturation of chemically denatured proteins
  • In its cellular structure role, there is evidence suggesting NPM1 is associated with the centrosome, and is the substrate of CDK2/cyclin E during duplication of centrosomes (cellular division)
  • Due to the NPM1 gene interaction with several tumor-associated chromosome translocations, NPM1 is thought to be a portion of several fusion proteins: NPM-ALK, NPM-RAR, and NPM-MLF1
  • While it is not thought to be part of the transforming potential of these fusion proteins, NPM1 is believed to act as the interface for oligomerization and oncogenic conversion of these tumor promoting fusion proteins
  • Further, NPM1 is also known to sequester the tumor suppressor RF in the nucleolus, protecting it from degradation until it is necessary
  • Dysfunction of the NPM1 protein is associated with diseases such as acute myeloid leukemia and lymphomatoid papulosis.

Compare Similar Items

Show Difference

Img

Bioss

50-198-5296

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Antigen:
Phospho-Nucleophosmin (Ser4)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPM1

Gene Alias:
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; NPM; Npm1; Nucleolar phosphoprotein B23; nucleolar protein B23.1; Nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; Numatrin; numatrin antibody; testicular tissue protein Li 128

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4869

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P06748

Gene Symbols:
NPM1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Nucleophosmin around the phosphorylation site of Ser4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5297

--


Antigen:
Phospho-NPM (Thr95)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPM1

Gene Alias:
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; NPM; Npm1; Nucleolar phosphoprotein B23; nucleolar protein B23.1; Nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; Numatrin; numatrin antibody; testicular tissue protein Li 128

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4869

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P06748

Gene Symbols:
NPM1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human NPM around the phosphorylation site of Thr95.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioworld

50-198-530

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Antigen:
__

Classification:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

Form:
__

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Isotype:
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Img

Bioss

50-198-5300

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Antigen:
Phospho-NuMA (Ser395)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUMA1

Gene Alias:
6720401E04Rik; AA764025; AL022610; AU014979; centrophilin stabilizes mitotic spindle in mitotic cells; NMP22; NMP-22; Nuclear matrix protein-22; Nuclear mitotic apparatus protein; Nuclear mitotic apparatus protein 1; NUMA; NuMA protein; NUMA1; SP-H antigen; structural nuclear protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4926

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q14980

Gene Symbols:
NUMA1

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human NuMA around the phosphorylation site of Ser395.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG