50-198-5395
Phospho-Stat4 (Tyr693) Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-5395-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-5395 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
Phospho-Stat4 (Tyr693)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STAT4
Gene Alias
CIS4; HSPC060; OTTHUMP00000163553; Signal transducer and activator of transcription 4; SLEB11; SOCS4; SOCS6; SSI4; STAI4; STAT; STAT4; STATI4
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
6775
Content And Storage
-20°C
Form
Liquid
Applications
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q14765
Gene Symbols
STAT4
Immunogen
KLH conjugated synthetic phosphopeptide derived from human Stat4 around the phosphorylation site of Tyr693.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- STAT4 was originally identified using degenerate primers complementary to sequences encoding conserved regions of other STAT proteins
- The STAT4 protein is most similar to STAT1 (52%) and STAT3 (47%)
- Functionally, STAT4 is similar to other STAT family members in that it can be tyrosine phosphorylated by Jak1 or Jak2
- STAT4 forms homodimers and heterodimers with related STAT family members
- Tyrosine phosphorylated STAT4 can bind the IFN-gamma activated site (GAS)
- Serine phosphorylation of STAT is also required for maximal transcriptional activity
- STAT4 expression is restricted to the thymus, spleen and testis
- Until recently the cytokine(s) responsible for activation of STAT4 had not been identified
- STAT4 is now known to be activated by the cytokine interleukin 12 (IL-12)
- IL-12 is required for the T-cell independent induction of IFN-gamma which is a key step in the initial suppression of bacterial and parasitic infections
- In addition, IL-12 is required for the development of a Th1 response which is necessary for effective host defense against intracellular pathogens
- STAT4-deficient mice display impaired IL-12 development of Th1 cells and enhanced development of Th2 cells
- A recent study in mouse has shown that in response to viral infection IFN-a/b activation of STAT4 is required for IFN-g production.
Compare Similar Items
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Antigen: Phospho-Stat4 (Tyr693)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT4
Gene Alias: CIS4; HSPC060; OTTHUMP00000163553; Signal transducer and activator of transcription 4; SLEB11; SOCS4; SOCS6; SSI4; STAI4; STAT; STAT4; STATI4
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6775
Content And Storage: -20°C
Form: Liquid
Applications: ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q14765
Gene Symbols: STAT4
Immunogen: KLH conjugated synthetic phosphopeptide derived from human Stat4 around the phosphorylation site of Tyr693.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Stat4 (Tyr693)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT4
Gene Alias:
CIS4; HSPC060; OTTHUMP00000163553; Signal transducer and activator of transcription 4; SLEB11; SOCS4; SOCS6; SSI4; STAI4; STAT; STAT4; STATI4
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6775
Content And Storage:
-20°C
Form:
Liquid
Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q14765
Gene Symbols:
STAT4
Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Stat4 around the phosphorylation site of Tyr693.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Syk (Tyr525, Tyr526)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Syk
Gene Alias: DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; Spleen tyrosine kinase; Syk; Sykb; Tyrosine-protein kinase SYK
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 20963, 25155, 6850
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P43405, P48025, Q64725
Gene Symbols: Syk
Immunogen: KLH conjugated synthetic phosphopeptide derived from human Syk around the phosphorylation site of Tyr525/526.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Syk (Tyr525, Tyr526)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Syk
Gene Alias:
DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; Spleen tyrosine kinase; Syk; Sykb; Tyrosine-protein kinase SYK
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
20963, 25155, 6850
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P43405, P48025, Q64725
Gene Symbols:
Syk
Immunogen:
KLH conjugated synthetic phosphopeptide derived from human Syk around the phosphorylation site of Tyr525/526.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-TAK1 (Thr184)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAP3K7
Gene Alias: B430101B05; BOS_9732; C87327; hypothetical protein LOC553788; I79_000697; M3K7; Map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; Mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; TAK1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; Transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6885
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: O43318
Gene Symbols: MAP3K7
Immunogen: KLH conjugated synthetic phosphopeptide derived from human TAK1 around the phosphorylation site of Thr184.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TAK1 (Thr184)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAP3K7
Gene Alias:
B430101B05; BOS_9732; C87327; hypothetical protein LOC553788; I79_000697; M3K7; Map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; Mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; TAK1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; Transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6885
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
O43318
Gene Symbols:
MAP3K7
Immunogen:
KLH conjugated synthetic phosphopeptide derived from human TAK1 around the phosphorylation site of Thr184.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
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