50-198-5596

Phospho-P53 (Ser33) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-5596-Each-of-1 In Stock ₹ 36,897.75

50-198-5596 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-P53 (Ser33)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Tp53

Gene Alias

53BP1; Antigen NY-CO-13; bbl; BCC7; bfy; bhy; BOS_18908; Cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; m53BP1; murine p53-binding protein; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; P53; p53 cellular tumor antigen; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; p53-binding protein 1; p53BP1; Phosphoprotein p53; tp53; tp53.L; TP53-binding protein 1; Tp53bp1; transformation related protein 53; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; transformation-related protein 53; Trp248; Trp53; Trp53bp1; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; Tumor suppressor p53; tumor suppressor p53-binding protein 1; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7157

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

P04637

Gene Symbols

Tp53

Immunogen

KLH conjugated synthetic phosphopeptide derived from human P53 around the phosphorylation site of Ser33.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The tumor suppressor protein, p53, is a sequence specific transcription factor that is activated by cellular stress
  • p53 mediates cell cycle arrest or apoptosis in response to DNA damage or starvation for pyrimidine nucleotides
  • p53 is up-regulated in response to stress signals and stimulated to activate transcription of specific genes, resulting in expression of p21waf1 and other proteins involved in G1 or G2/M arrest
  • The structure of p53 comprises an N-terminal transactivation domain, a central DNA-binding domain, an oligomerisation domain, and a C-terminal regulatory domain
  • There are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and stabilization
  • p53 has been characterized to play a role in blocking the proliferative action of damaged cells and act as an anticancer agent
  • Phosphorylation of Ser392 in p53 has been shown to associate with the formation of human tumors
  • In addition, p53 has also been linked to the effects of aging and oxidative stress and an increase in p53 has been linked to deficits in LTP (Long Term Potentiation) in learning and memory
  • p53 is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy
  • Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and cause the loss of tumor suppressor activity
  • Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families such as Li-Fraumeni syndrome.

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Bioss

50-198-5596

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Antigen:
Phospho-P53 (Ser33)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tp53

Gene Alias:
53BP1; Antigen NY-CO-13; bbl; BCC7; bfy; bhy; BOS_18908; Cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; m53BP1; murine p53-binding protein; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; P53; p53 cellular tumor antigen; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; p53-binding protein 1; p53BP1; Phosphoprotein p53; tp53; tp53.L; TP53-binding protein 1; Tp53bp1; transformation related protein 53; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; transformation-related protein 53; Trp248; Trp53; Trp53bp1; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; Tumor suppressor p53; tumor suppressor p53-binding protein 1; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P04637

Gene Symbols:
Tp53

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human P53 around the phosphorylation site of Ser33.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5597

--


Antigen:
Phospho-P53 (Ser46)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tp53

Gene Alias:
53BP1; Antigen NY-CO-13; bbl; BCC7; bfy; bhy; BOS_18908; Cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; m53BP1; murine p53-binding protein; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; P53; p53 cellular tumor antigen; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; p53-binding protein 1; p53BP1; Phosphoprotein p53; tp53; tp53.L; TP53-binding protein 1; Tp53bp1; transformation related protein 53; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; transformation-related protein 53; Trp248; Trp53; Trp53bp1; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; Tumor suppressor p53; tumor suppressor p53-binding protein 1; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P04637

Gene Symbols:
Tp53

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human P53 around the phosphorylation site of Ser46.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5598

--


Antigen:
Phospho-P53 (Thr18)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tp53

Gene Alias:
53BP1; Antigen NY-CO-13; bbl; BCC7; bfy; bhy; BOS_18908; Cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; m53BP1; murine p53-binding protein; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; P53; p53 cellular tumor antigen; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; p53-binding protein 1; p53BP1; Phosphoprotein p53; tp53; tp53.L; TP53-binding protein 1; Tp53bp1; transformation related protein 53; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; transformation-related protein 53; Trp248; Trp53; Trp53bp1; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; Tumor suppressor p53; tumor suppressor p53-binding protein 1; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P04637

Gene Symbols:
Tp53

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human P53 around the phosphorylation site of Thr18.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5599

--


Antigen:
Phospho-P53 (Thr81)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tp53

Gene Alias:
53BP1; Antigen NY-CO-13; bbl; BCC7; bfy; bhy; BOS_18908; Cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; m53BP1; murine p53-binding protein; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; P53; p53 cellular tumor antigen; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; p53-binding protein 1; p53BP1; Phosphoprotein p53; tp53; tp53.L; TP53-binding protein 1; Tp53bp1; transformation related protein 53; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; transformation-related protein 53; Trp248; Trp53; Trp53bp1; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; Tumor suppressor p53; tumor suppressor p53-binding protein 1; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7157

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P04637

Gene Symbols:
Tp53

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human P53 around the phosphorylation site of Thr81.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG