50-198-5685

AMBRA1 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-5685-Each-of-1 In Stock ₹ 36,897.75

50-198-5685 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

AMBRA1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AMBRA1

Gene Alias

2310079H06Rik; A130023A14; AA474864; activating molecule in beclin-1-regulated autophagy; activating molecule in Beclin1-regulated autophagy; Activating molecule in BECN1-regulated autophagy protein 1; AMBRA1; autophagy and beclin 1 regulator 1; autophagy/beclin 1 regulator 1; autophagy/beclin-1 regulator 1; AV021921; BOS_15131; D030051N19Rik; DCAF3; DDB1 and CUL4 associated factor 3; ischemia related factor NYW-1; KIAA1736; mKIAA1736; Nyw1; RCJMB04_3b24; WD repeat domain 94; WDR94

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

55626

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q9C0C7

Gene Symbols

AMBRA1

Immunogen

KLH conjugated synthetic peptide derived from human AMBRA1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells
  • It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components
  • Beclin-1, a principal regulator of autophagosome formation, is in turn regulated by Ambra1
  • Ambra1 associates with Beclin-1 through a region near its center as determined by yeast two-hybrid assay
  • Null mutations in this gene in mice resulted in embryonic lethality with severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic death
  • Furthermore, down-regulation of Ambra1 in cultured cells though RNA interference decreased the level of rapamycin- and nutrient starvation-induced autophagy
  • Multiple isoforms of Ambra1 are known to exist.

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Img

Bioss

50-198-5685

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Antigen:
AMBRA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AMBRA1

Gene Alias:
2310079H06Rik; A130023A14; AA474864; activating molecule in beclin-1-regulated autophagy; activating molecule in Beclin1-regulated autophagy; Activating molecule in BECN1-regulated autophagy protein 1; AMBRA1; autophagy and beclin 1 regulator 1; autophagy/beclin 1 regulator 1; autophagy/beclin-1 regulator 1; AV021921; BOS_15131; D030051N19Rik; DCAF3; DDB1 and CUL4 associated factor 3; ischemia related factor NYW-1; KIAA1736; mKIAA1736; Nyw1; RCJMB04_3b24; WD repeat domain 94; WDR94

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55626

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9C0C7

Gene Symbols:
AMBRA1

Immunogen:
KLH conjugated synthetic peptide derived from human AMBRA1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5687

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Antigen:
RHEB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RHEB

Gene Alias:
GTP-binding protein Rheb; Ras homolog enriched in brain; Ras homolog enriched in brain 2; RAS-homolog enriched in brain; RHEB; Rheb1; RHEB2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6009

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q15382

Gene Symbols:
RHEB

Immunogen:
KLH conjugated synthetic peptide derived from human RHEB.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5689

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Antigen:
MrpL39

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MRPL39

Gene Alias:
39S ribosomal protein L39, mitochondrial; 39S ribosomal protein L5, mitochondrial; C21orf8; C21orf92; L39mt; L5mt; Mitochondrial large ribosomal subunit protein mL39; mitochondrial ribosomal protein L39; MRPL39; MRP-L39; MRPL5; MRP-L5; MSTP003; ORF22; PRED22; PRED66; ribosomal protein, mitochondrial, L5; RPML5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
54148

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9NYK5

Gene Symbols:
MRPL39

Immunogen:
KLH conjugated synthetic peptide derived from human MrpL-39 .

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioworld

50-198-569

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