50-198-5691
Hamartin/TSC1 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-5691-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-5691 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
Hamartin/TSC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TSC1
Gene Alias
Hamartin; HGNC:12362; KIAA0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; TSC1; tuberous sclerosis 1; Tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
7248
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin)
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q92574
Gene Symbols
TSC1
Immunogen
KLH conjugated synthetic peptide derived from human Hamartin .
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes
- The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors
- TOR activity is stimulated by Rheb, a member of the Ras superfamily of G-proteins, when the GTP/GDP ratio bound to Rheb is high
- Immunoprecipitated TSC1/TSC2 has been shown to stimulate Rheb GTPase activity in vitro, suggesting that the TSC1/TSC2 decreases the ability of Rheb to stimulate TOR activity
- This is supported by experiments showing overexpression of TSC1 and TSC2 results in a significant decrease in the GTP/GDP ratio bound to Rheb and the inhibition of cell growth
- A shorter 40 kDa isoform of TSC1 has been shown to exist but its function is unknown.
Compare Similar Items
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Antigen: Hamartin/TSC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSC1
Gene Alias: Hamartin; HGNC:12362; KIAA0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; TSC1; tuberous sclerosis 1; Tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7248
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q92574
Gene Symbols: TSC1
Immunogen: KLH conjugated synthetic peptide derived from human Hamartin .
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Hamartin/TSC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSC1
Gene Alias:
Hamartin; HGNC:12362; KIAA0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; TSC1; tuberous sclerosis 1; Tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7248
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q92574
Gene Symbols:
TSC1
Immunogen:
KLH conjugated synthetic peptide derived from human Hamartin .
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: e3A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EIF3A
Gene Alias: 150/170; A830012B05Rik; Centrosomin; centrosomin homolog; Csma; cytoplasmic protein p167; Eif3; eIF3 p167; eIF3 p180; eIF3 p185; EIF3, p180 subunit; EIF3A; eIF3a {ECO:0000255; eIF3-p170; EIF3S10; eIF-3-theta; eIF3-theta; eIF-3-theta {ECO:0000255; Eukaryotic translation initiation factor 3 subunit 10; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN); eukaryotic translation initiation factor 3 subunit 10 {ECO:0000255; Eukaryotic translation initiation factor 3 subunit A; eukaryotic translation initiation factor 3 subunit A {ECO:0000255; eukaryotic translation initiation factor 3, subunit 10 (theta); eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD); eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD); eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa; eukaryotic translation initiation factor 3, subunit 10, 170kD; eukaryotic translation initiation factor 3, subunit A; HAMAP-Rule:MF_03000}; KIAA0139; mKIAA0139; p162; P167; p180; p185; TIF32; ZH12
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 8661
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q14152
Gene Symbols: EIF3A
Immunogen: KLH conjugated synthetic peptide derived from human eIF3A.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
e3A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EIF3A
Gene Alias:
150/170; A830012B05Rik; Centrosomin; centrosomin homolog; Csma; cytoplasmic protein p167; Eif3; eIF3 p167; eIF3 p180; eIF3 p185; EIF3, p180 subunit; EIF3A; eIF3a {ECO:0000255; eIF3-p170; EIF3S10; eIF-3-theta; eIF3-theta; eIF-3-theta {ECO:0000255; Eukaryotic translation initiation factor 3 subunit 10; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN); eukaryotic translation initiation factor 3 subunit 10 {ECO:0000255; Eukaryotic translation initiation factor 3 subunit A; eukaryotic translation initiation factor 3 subunit A {ECO:0000255; eukaryotic translation initiation factor 3, subunit 10 (theta); eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD); eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD); eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa; eukaryotic translation initiation factor 3, subunit 10, 170kD; eukaryotic translation initiation factor 3, subunit A; HAMAP-Rule:MF_03000}; KIAA0139; mKIAA0139; p162; P167; p180; p185; TIF32; ZH12
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
8661
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q14152
Gene Symbols:
EIF3A
Immunogen:
KLH conjugated synthetic peptide derived from human eIF3A.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: __
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Antigen: TMEFF2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMEFF2
Gene Alias: 4832418D20Rik; 7630402F16Rik; BOS_1920; cancer/testis antigen family 120, member 2; CT120.2; HPP1; Hyperplastic polyposis protein 1; MNCb-1026; TENB2; TMEFF2; tomoregulin; Tomoregulin-2; TPEF; TR; TR-2; transmembrane protein TENB2; transmembrane protein with EGF like and two follistatin like domains 2; Transmembrane protein with EGF-like and two follistatin-like domains; transmembrane protein with EGF-like and two follistatin-like domains 2; UNQ178/PRO204
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23671
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q9UIK5
Gene Symbols: TMEFF2
Immunogen: KLH conjugated synthetic peptide derived from human TMEFF2 .
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TMEFF2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMEFF2
Gene Alias:
4832418D20Rik; 7630402F16Rik; BOS_1920; cancer/testis antigen family 120, member 2; CT120.2; HPP1; Hyperplastic polyposis protein 1; MNCb-1026; TENB2; TMEFF2; tomoregulin; Tomoregulin-2; TPEF; TR; TR-2; transmembrane protein TENB2; transmembrane protein with EGF like and two follistatin like domains 2; Transmembrane protein with EGF-like and two follistatin-like domains; transmembrane protein with EGF-like and two follistatin-like domains 2; UNQ178/PRO204
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23671
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q9UIK5
Gene Symbols:
TMEFF2
Immunogen:
KLH conjugated synthetic peptide derived from human TMEFF2 .
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG