50-198-5822

Phospho-CHK2 (Ser19) Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-5822-Each-of-1 In Stock ₹ 36,897.75

50-198-5822 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

Phospho-CHK2 (Ser19)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Chek2

Gene Alias

CDS1; Cds1 homolog; Checkpoint kinase 2; checkpoint-like protein CHK2; Chek2; CHK2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; Hucds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; RAD53; Rad53 homolog; RP11-436C9.1; Serine/threonine-protein kinase Chk2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

11200

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O96017

Gene Symbols

Chek2

Immunogen

KLH conjugated synthetic phosphopeptide derived from human CHK2 around the phosphorylation site of ser19.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Checkpoint kinase 2 (Chk2) is a serine/threonine-protein kinase which functions as a cell cycle checkpoint regulator
  • ATM and ATR kinases are activated in response to ionizing and ultraviolet radition, and phosphorylate Thr68 and other sites in the amino-terminal region of Chk2 dimerisation and activation
  • Activated Chk2 phosphorylates and inhibits Cdc25C phosphates, preventing the entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1
  • In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage
  • Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53
  • Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.

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Bioss

50-198-5822

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Antigen:
Phospho-CHK2 (Ser19)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chek2

Gene Alias:
CDS1; Cds1 homolog; Checkpoint kinase 2; checkpoint-like protein CHK2; Chek2; CHK2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; Hucds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; RAD53; Rad53 homolog; RP11-436C9.1; Serine/threonine-protein kinase Chk2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11200

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O96017

Gene Symbols:
Chek2

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human CHK2 around the phosphorylation site of ser19.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5824

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Antigen:
Phospho-AMPK alpha-1/2 (Thr172, Thr183)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKAB2

Gene Alias:
1300015D22Rik; 5730553K21Rik; 5′-AMP-activated protein kinase 40 kDa subunit; 5-AMP-activated protein kinase beta subunit; 5′-AMP-activated protein kinase beta-1 subunit; 5′-AMP-activated protein kinase subunit beta-1; 5′-AMP-activated protein kinase subunit beta-1-like protein; 5′-AMP-activated protein kinase subunit beta-2; 5′-AMP-activated protein kinase, beta subunit; 5′-AMP-activated protein kinase, beta-2 subunit; AMP-activated protein kinase beta 2 non-catalytic subunit; AMP-activated protein kinase beta subunit; AMP-activated protein kinase beta-2 regulatory subunit; AMPK; AMPK beta 1; AMPK beta -1 chain; AMPK beta 2; AMPK beta-1 chain; AMPK beta-2 chain; AMPK subunit beta-1; AMPK subunit beta-2; AMPKb; AU021155; AW049591; BB124140; E430008F22; HAMPKb; I79_012592; Prkab1; PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 1; protein kinase AMP-activated non-catalytic subunit beta 2; protein kinase, AMP-activated, beta 1 non-catalytic subunit; protein kinase, AMP-activated, beta 2 non-catalytic subunit; protein kinase, AMP-activated, noncatalytic, beta-1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5564, 5565

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O43741, Q9Y478

Gene Symbols:
Prkab1, PRKAB2

Immunogen:
KLH conjugated synthetic phosphopeptide derived from mouse AMPK alpha 2 around the phosphorylation site of Thr172.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5826

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Antigen:
Phospho-HER2 (Thr686)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERBB2

Gene Alias:
avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); CD antigen CD340; CD340; c-erb B2/neu protein; c-erbB2; c-erbB-2; c-neu; epidermal growth factor receptor-related protein; ERBB2; Erbb-2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; erb-b2 receptor tyrosine kinase 2; HER2; HER-2; HER-2/neu; herstatin; human epidermal growth factor receptor 2; Kiaa3023; metas; Metastatic lymph node gene 19 protein; mKIAA3023; MLN 19; MLN19; NEU; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; NGL; p185erbB2; p185neu; phospho ErbB2; Proto-oncogene c-ErbB-2; Proto-oncogene Neu; Receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2064

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
P04626

Gene Symbols:
ERBB2

Immunogen:
KLH conjugated synthetic phosphopeptide derived from human HER2 around the phosphorylation site of Thr686.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5829

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Antigen:
ATG16L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATG16L1

Gene Alias:
1500009K01Rik; A16L1; APG 16-L1; Apg16l; APG16L beta; APG16L isoforms 1; APG16-like 1; ATG16 autophagy related 16-like 1; ATG16A; ATG16L; ATG16L1; Atg16L1 gamma; autophagy related 16 like 1; autophagy related 16-like 1; autophagy related 16-like 1 (S. cerevisiae); autophagy-related 16-like 1; autophagy-related 16-like 1 gamma; Autophagy-related protein 16-1; hCG_1817841; IBD10; UNQ9393/PRO34307; WD repeat domain 30; Wdr30

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55054

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q676U5

Gene Symbols:
ATG16L1

Immunogen:
KLH conjugated synthetic peptide derived from human ATG16A.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG