50-198-5885

LATS1/2 Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

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Pack Size SKU Availability Price
Each of 1 50-198-5885-Each-of-1 In Stock ₹ 36,897.75

50-198-5885 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

LATS1/2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LATS1

Gene Alias

AW208599; h-warts; large tumor suppressor; Large tumor suppressor homolog 1; large tumor suppressor kinase 1; large tumor supressor, homolog 1; LATS (large tumor suppressor, Drosophila) homolog 1; LATS, large tumor suppressor, homolog 1; Lats1; RGD1564085; Serine/threonine-protein kinase LATS1; WARTS; WARTS protein kinase; wts

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

9113

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

O95835

Gene Symbols

LATS1

Immunogen

KLH conjugated synthetic peptide derived from human LATS2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • LATS1 is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis
  • The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase
  • The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A
  • In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding
  • Biochemical and genetic data suggest a role as a tumor suppressor
  • This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments.

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Img

Bioss

50-198-5885

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Antigen:
LATS1/2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LATS1

Gene Alias:
AW208599; h-warts; large tumor suppressor; Large tumor suppressor homolog 1; large tumor suppressor kinase 1; large tumor supressor, homolog 1; LATS (large tumor suppressor, Drosophila) homolog 1; LATS, large tumor suppressor, homolog 1; Lats1; RGD1564085; Serine/threonine-protein kinase LATS1; WARTS; WARTS protein kinase; wts

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9113

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O95835

Gene Symbols:
LATS1

Immunogen:
KLH conjugated synthetic peptide derived from human LATS2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5889

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Antigen:
SPTLC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Sptlc1

Gene Alias:
AW552086; BOS_9235; C77762; E030036H05; fc75h04; fp41c08; hLCB1; HSAN; HSAN1; HSN1; hypothetical protein LOC553981; LBC1; LCB 1; LCB1; Long chain base biosynthesis protein 1; MGC14645; rCG_44191; RGD1306617; RP11-118F2.1; serine C-palmitoyltransferase; Serine palmitoyltransferase 1; serine palmitoyltransferase long chain base subunit 1; serine palmitoyltransferase subunit 1; serine palmitoyltransferase, long chain base subunit 1; Serine-palmitoyl-CoA transferase 1; SPT 1; SPT1; SPTI; SPTLC1; wu:fc75h04; wu:fp41c08; zgc:112247

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10558

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
O15269

Gene Symbols:
Sptlc1

Immunogen:
KLH conjugated synthetic peptide derived from human SPTLC1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5890

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Antigen:
ANAPC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ANAPC1

Gene Alias:
2610021O03Rik; AI047775; AI853536; Anapc1; anaphase promoting complex subunit 1; anaphase-promoting complex 1 (meiotic checkpoint regulator); Anaphase-promoting complex subunit 1; APC1; AW547281; Cyclosome subunit 1; Mcpr; meiotic check point regulator; Mitotic checkpoint regulator; Testis-specific gene 24 protein; Tsg24

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
64682

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9H1A4

Gene Symbols:
ANAPC1

Immunogen:
KLH conjugated synthetic peptide derived from human ANAPC1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-5891

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Antigen:
ASAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ASAP1

Gene Alias:
130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein; 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein; ADP-ribosylation factor-directed GTPase-activating protein 1; AMAP1; ARF GTPase-activating protein 1; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1; ArfGAP with SH3 domain, ankyrin repeat and PH domain 1; ArfGAP with SH3 domain, ankyrin repeat and PH domain1; ASAP1; AV239055; centaurin, beta 4; CENTB4; Ddef1; DEF-1; development and differentiation enhancing factor 1; Development and differentiation-enhancing factor 1; differentiation-enhancing factor 1; Kiaa1249; mKIAA1249; PAG2; PAP; PIP2-dependent ARF1 GAP; s19; Shag1; ZG14P

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
50807

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9ULH1

Gene Symbols:
ASAP1

Immunogen:
KLH conjugated synthetic peptide derived from human ASAP1 .

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG