50-198-5922
MAP4K1 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-5922-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-5922 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
MAP4K1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAP4K1
Gene Alias
EC 2.7.11.1; Hematopoietic progenitor kinase; hematopoietic progenitor kinase 1; HPK; Hpk1; MAP4K1; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1; mHPK1; mitogen activated protein kinase kinase kinase kinase 1; Mitogen-activated protein kinase kinase kinase kinase 1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
11184
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
Q92918
Gene Symbols
MAP4K1
Immunogen
KLH conjugated synthetic peptide derived from human MAP4K1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The c-Jun amino-terminal kinases (JNKs)/stress-activated protein kinases (SAPKs) play a crucial role in stress responses in mammalian cells
- The mechanism underlying this pathway in the hematopoietic system is unclear, but it is a key in understanding the molecular basis of blood cell differentiation
- We have cloned a novel protein kinase, termed hematopoietic progenitor kinase 1 (HPK1), that is expressed predominantly in hematopoietic cells, including early progenitor cells
- HPK1 is related distantly to the p21(Cdc42/Rac1)-activated kinase (PAK) and yeast STE20 implicated in the mitogen-activated protein kinase (MAPK) cascade
- Expression of HPK1 activates JNK1 specifically, and it elevates strongly AP-1-mediated transcriptional activity in vivo
- HPK1 binds and phosphorylates MEKK1 directly, whereas JNK1 activation by HPK1 is inhibited by a dominant-negative MEKK1 or MKK4/SEK mutant
- Interestingly, unlike PAK65, HPK1 does not contain the small GTPase Rac1/Cdc42-binding domain and does not bind to either Rac1 or Cdc42, suggesting that HPK1
- activation is Rac1/Cdc42-independent
- These results indicate that HPK1 is a novel functional activator of the JNK/SAPK signaling pathway.
Compare Similar Items
Show Difference
Antigen: MAP4K1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAP4K1
Gene Alias: EC 2.7.11.1; Hematopoietic progenitor kinase; hematopoietic progenitor kinase 1; HPK; Hpk1; MAP4K1; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1; mHPK1; mitogen activated protein kinase kinase kinase kinase 1; Mitogen-activated protein kinase kinase kinase kinase 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 11184
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q92918
Gene Symbols: MAP4K1
Immunogen: KLH conjugated synthetic peptide derived from human MAP4K1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MAP4K1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAP4K1
Gene Alias:
EC 2.7.11.1; Hematopoietic progenitor kinase; hematopoietic progenitor kinase 1; HPK; Hpk1; MAP4K1; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1; mHPK1; mitogen activated protein kinase kinase kinase kinase 1; Mitogen-activated protein kinase kinase kinase kinase 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
11184
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q92918
Gene Symbols:
MAP4K1
Immunogen:
KLH conjugated synthetic peptide derived from human MAP4K1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MEF2D
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MEF2D
Gene Alias: BOS_2847; C80750; DKFZp686I1536; LOC100340589; MADS box transcription enhancer factor 2, polypeptide D; MEF2D; MEF2D/DAZAP1 fusion; myocyte enhancer factor 2D; myocyte enhancer factor 2D-like; Myocyte-specific enhancer factor 2D
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4209
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q14814
Gene Symbols: MEF2D
Immunogen: KLH conjugated synthetic peptide derived from human MEF2D.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MEF2D
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MEF2D
Gene Alias:
BOS_2847; C80750; DKFZp686I1536; LOC100340589; MADS box transcription enhancer factor 2, polypeptide D; MEF2D; MEF2D/DAZAP1 fusion; myocyte enhancer factor 2D; myocyte enhancer factor 2D-like; Myocyte-specific enhancer factor 2D
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4209
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q14814
Gene Symbols:
MEF2D
Immunogen:
KLH conjugated synthetic peptide derived from human MEF2D.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MAPKAPK5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAPKAPK5
Gene Alias: MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAPK5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 8550
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: Q8IW41
Gene Symbols: MAPKAPK5
Immunogen: KLH conjugated synthetic peptide derived from human MAPKAPK5.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MAPKAPK5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAPKAPK5
Gene Alias:
MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; MAPKAPK5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
8550
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
Q8IW41
Gene Symbols:
MAPKAPK5
Immunogen:
KLH conjugated synthetic peptide derived from human MAPKAPK5.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: IKB epsilon
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Nfkbie
Gene Alias: ikappaBepsilon; I-kappa-B-epsilon; IkB epsilon; IKBE; IkB-E; IkBepsilon; ikB-epsilon; NF-kappa-B inhibitor epsilon; NF-kappa-BIE; NFKB inhibitor epsilon; NFKBIE; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon; Slc35b2; solute carrier family 35, member B2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4794
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: O00221
Gene Symbols: Nfkbie
Immunogen: KLH conjugated synthetic peptide derived from human IKB epsilon.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
IKB epsilon
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Nfkbie
Gene Alias:
ikappaBepsilon; I-kappa-B-epsilon; IkB epsilon; IKBE; IkB-E; IkBepsilon; ikB-epsilon; NF-kappa-B inhibitor epsilon; NF-kappa-BIE; NFKB inhibitor epsilon; NFKBIE; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon; Slc35b2; solute carrier family 35, member B2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4794
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
O00221
Gene Symbols:
Nfkbie
Immunogen:
KLH conjugated synthetic peptide derived from human IKB epsilon.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG