50-198-6027

CHFR Rabbit anti-Human, Polyclonal, Bioss

Manufacturer: Bioss

Select a Size

Pack Size SKU Availability Price
Each of 1 50-198-6027-Each-of-1 In Stock ₹ 36,897.75

50-198-6027 - Each of 1

₹ 36,897.75

In Stock

Quantity

1

Base Price: ₹ 36,897.75

GST (18%): ₹ 6,641.595

Total Price: ₹ 43,539.345

Antigen

CHFR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Chfr

Gene Alias

5730484M20Rik; BOS_16426; C230082M18; checkpoint with forkhead and ring finger domains; Checkpoint with forkhead and RING finger domains protein; checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase; chfr; E3 ubiquitin-protein ligase CHFR; fc43f10; FLJ10796; FLJ33629; RING finger protein 196; RING-type E3 ubiquitin transferase CHFR; RNF116; RNF196; si:dkey-69h6.7; wu:fc43f10

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

55743

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.

Q96EP1

Gene Symbols

Chfr

Immunogen

KLH conjugated synthetic peptide derived from human CHFR.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Bioss

50-198-8346

--

Img

Bioss

50-198-5644

--

Img

Bioss

50-198-8973

--

Img

Bioss

50-198-8345

--

Img

Bioss

50-198-8189

--

Img

Bioss

50-198-8312

--

Img

Bioss

50-198-8305

--

Img

Bioss

50-198-8311

--

Description

  • E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons
  • Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus
  • Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the ′Lys-48′-linked ubiquitination of target proteins, leading to their degradation by the proteasome
  • Promotes the ubiquitination and subsequent degradation of AURKA and PLK1
  • Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1, leading to its degradation
  • May also promote the formation of ′Lys-63′-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer
  • Substrates that are polyubiquitinated at ′Lys-63′ are usually not targeted for degradation, but are rather involved in signaling cellular stress.

Compare Similar Items

Show Difference

Img

Bioss

50-198-6027

--


Antigen:
CHFR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chfr

Gene Alias:
5730484M20Rik; BOS_16426; C230082M18; checkpoint with forkhead and ring finger domains; Checkpoint with forkhead and RING finger domains protein; checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase; chfr; E3 ubiquitin-protein ligase CHFR; fc43f10; FLJ10796; FLJ33629; RING finger protein 196; RING-type E3 ubiquitin transferase CHFR; RNF116; RNF196; si:dkey-69h6.7; wu:fc43f10

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55743

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q96EP1

Gene Symbols:
Chfr

Immunogen:
KLH conjugated synthetic peptide derived from human CHFR.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6028

--


Antigen:
PIH1D1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PIH1D1

Gene Alias:
1110061L23Rik; 4933413A04Rik; NOP17; Nucleolar protein 17 homolog; PIH1 domain containing 1; PIH1 domain-containing protein 1; PIH1D1; RGD1309809

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55011

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9NWS0

Gene Symbols:
PIH1D1

Immunogen:
KLH conjugated synthetic peptide derived from human PIH1D1/NOP17.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6030

--


Antigen:
ELAC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Elac2

Gene Alias:
1110017O07Rik; COXPD17; D11Wsu80e; elaC homolog 2; elaC homolog 2 (E. coli); ElaC homolog protein 2; elaC ribonuclease Z 2; ELAC2; elaC-like protein 2; ELC2; Heredity prostate cancer protein 2; HPC2; putative prostate cancer susceptibility protein HPC2/ELAC2; Ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z (long form); tRNase Z 2; tRNase Z(L); Zinc phosphodiesterase ELAC protein 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
60528

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q9BQ52

Gene Symbols:
Elac2

Immunogen:
KLH conjugated synthetic peptide derived from human ELAC2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bioss

50-198-6031

--


Antigen:
ENPP7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ENPP7

Gene Alias:
Alkaline sphingomyelin phosphodiesterase; alkaline sphingomyelinase; Alk-SMase; ectonucleotide pyrophosphatase/phosphodiesterase 7; Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; E-NPP 7; ENPP7; E-NPP7; Gm254; Intestinal alkaline sphingomyelinase; NPP7; NPP-7; sphingomyelinase, intestinal alkaline; UNQ3077/PRO9912

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
339221

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH

Gene Accession No.:
Q6UWV6

Gene Symbols:
ENPP7

Immunogen:
KLH conjugated synthetic peptide derived from human ENPP7.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG