50-198-6144
MRC1 Rabbit anti-Human, Polyclonal, Bioss
Manufacturer: Bioss
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-198-6144-Each-of-1 | In Stock | ₹ 36,897.75 |
50-198-6144 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,897.75
GST (18%): ₹ 6,641.595
Total Price: ₹ 43,539.345
Antigen
MRC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Mrc1
Gene Alias
AW259686; bA541I19.1; CD206; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; hMR; Human mannose receptor; Macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; MMR; MR; MRC1; MRC1L1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
4360
Content And Storage
-20°C
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.
P22897
Gene Symbols
Mrc1
Immunogen
KLH conjugated synthetic peptide derived from human MRC1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- CD206 (MSR, Mannose receptor, MRC1) is a 175 kDa transmembrane protein belonging to the group of pattern recognition receptors
- CD206 is predominantly expressed in tissue macrophages, dendritic cells, a subpopulation of endothelial cells and sperm cells
- CD206 is thought to play a role in the innate and adaptive immune response
- CD206 is also expressed on microglia and mato cells of the brain but not astrocytes or neurons
- CD206 also mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta)
- While the normal role of CD206 is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Amyloid beta deposition in Alzheimer′s disease (AD)
- CD206’s gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing
- The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs)
- The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms
- CD206 has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis
- The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages
- Other diseases associated with CD206 dysfunction include leprosy and Gaucher’s Disease.
Compare Similar Items
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Antigen: MRC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mrc1
Gene Alias: AW259686; bA541I19.1; CD206; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; hMR; Human mannose receptor; Macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; MMR; MR; MRC1; MRC1L1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4360
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P22897
Gene Symbols: Mrc1
Immunogen: KLH conjugated synthetic peptide derived from human MRC1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MRC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mrc1
Gene Alias:
AW259686; bA541I19.1; CD206; CLEC13D; CLEC13DL; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; hMR; Human mannose receptor; Macrophage mannose receptor 1; Macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1; mannose receptor, C type 1-like 1; MMR; MR; MRC1; MRC1L1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4360
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P22897
Gene Symbols:
Mrc1
Immunogen:
KLH conjugated synthetic peptide derived from human MRC1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Prion protein PrP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PRNP
Gene Alias: AA960666; AI325101; Alternative prion protein; alternative prion protein; major prion protein; ALTPRP; ASCR; BOS_13027; BSE; CD230; CD230 antigen; CJD; GSS; KURU; Major prion protein; Major scrapie-associated fibril protein 1; MGC26679; p27-30; PK resistant core; prion protein; prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia); prion protein precursor PrP; prion protein PrP; prion protein variant a; prion protein variant b; prion protein, PrP; prion protein, structural; prion-related protein; PRIP; Prn; Prn-i; PRNP; Prn-p; Prp; PrP; PrP27-30; PrP33-35C; PrPc; PrPSc; Sinc; SIP; TSE
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5621
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: F7VJQ1, P04156
Gene Symbols: PRNP
Immunogen: KLH conjugated synthetic peptide derived from human Major prion protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Prion protein PrP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PRNP
Gene Alias:
AA960666; AI325101; Alternative prion protein; alternative prion protein; major prion protein; ALTPRP; ASCR; BOS_13027; BSE; CD230; CD230 antigen; CJD; GSS; KURU; Major prion protein; Major scrapie-associated fibril protein 1; MGC26679; p27-30; PK resistant core; prion protein; prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia); prion protein precursor PrP; prion protein PrP; prion protein variant a; prion protein variant b; prion protein, PrP; prion protein, structural; prion-related protein; PRIP; Prn; Prn-i; PRNP; Prn-p; Prp; PrP; PrP27-30; PrP33-35C; PrPc; PrPSc; Sinc; SIP; TSE
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5621
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
F7VJQ1, P04156
Gene Symbols:
PRNP
Immunogen:
KLH conjugated synthetic peptide derived from human Major prion protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Bone Sialoprotein 1/2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ibsp
Gene Alias: BNSP; Bone sialoprotein 2; Bone sialoprotein II; Bsp; BSP II; Bsp2; BSPII; BSP-II; Cell-binding sialoprotein; IBSP; integrin binding sialoprotein; Integrin-binding sialoprotein; integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II); SP-II
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3381
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P21815
Gene Symbols: Ibsp
Immunogen: KLH conjugated synthetic peptide derived from mouse Bone Sialoprotein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Bone Sialoprotein 1/2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ibsp
Gene Alias:
BNSP; Bone sialoprotein 2; Bone sialoprotein II; Bsp; BSP II; Bsp2; BSPII; BSP-II; Cell-binding sialoprotein; IBSP; integrin binding sialoprotein; Integrin-binding sialoprotein; integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II); SP-II
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3381
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P21815
Gene Symbols:
Ibsp
Immunogen:
KLH conjugated synthetic peptide derived from mouse Bone Sialoprotein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ABP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AOC1
Gene Alias: 1600012D06Rik; Abp; ABP1; amiloride binding protein 1 (amine oxidase (copper-containing)); amiloride binding protein 1 (amine oxidase, copper-containing); amiloride binding protein 1-like; amiloride binding protein/diamine oxidase; Amiloride-binding protein 1; amiloride-sensitive amine oxidase; Amiloride-sensitive amine oxidase [copper-containing]; amine oxidase copper containing 1; Amine oxidase copper domain-containing protein 1; amine oxidase, copper containing 1; amine oxidase, copper-containing 1; AOC1; BOS_4752; DAO; DAO1; diamine oxidase; Histaminase; KAO; Kidney amine oxidase; LOC100347103; si:ch211-286c5.2; zgc:154101
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 26
Content And Storage: -20°C
Form: Liquid
Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
Concentration: 1 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.: P19801
Gene Symbols: AOC1
Immunogen: KLH conjugated synthetic peptide derived from Prunus persica ABP1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ABP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AOC1
Gene Alias:
1600012D06Rik; Abp; ABP1; amiloride binding protein 1 (amine oxidase (copper-containing)); amiloride binding protein 1 (amine oxidase, copper-containing); amiloride binding protein 1-like; amiloride binding protein/diamine oxidase; Amiloride-binding protein 1; amiloride-sensitive amine oxidase; Amiloride-sensitive amine oxidase [copper-containing]; amine oxidase copper containing 1; Amine oxidase copper domain-containing protein 1; amine oxidase, copper containing 1; amine oxidase, copper-containing 1; AOC1; BOS_4752; DAO; DAO1; diamine oxidase; Histaminase; KAO; Kidney amine oxidase; LOC100347103; si:ch211-286c5.2; zgc:154101
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
26
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)
Concentration:
1 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Accession No.:
P19801
Gene Symbols:
AOC1
Immunogen:
KLH conjugated synthetic peptide derived from Prunus persica ABP1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG